Prostate cancer that has spread to several lymph nodes and bones

Posted by longtravel @longtravel, 5 hours ago

I am wondering about the treatment for prostate cancer that has spread to several lymph nodes and bones. Just curious if they will start me on ADT and hormone treatment and then later do a chemo treatment
I’m trying to prepare myself

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

I was started on nubeqa orally and then eligard shots I decided to see an oncologist and now I'm taking docetaxel infusion every 3 was. Every dr is different but a good person to talk to on here is jeffmarc he is very helpful 🙏

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Probably a triplet therapy of ADT, chemo, and one medication like abiraterone, enzalutimide, darolutamide, etc.
Maybe even a radiogland like Lutitiem 177. Were your mets found via PSMA pet scan? That would find much more than conventional imaging ct/bone scans.

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Sorry you have to take this journey. More info would be helpful. Do you still have your prostate would be a major distinction. What was your Gleason score and are there any other factors determining aggressiveness would be another. I assume you've had a PSMA PET since you know it has metastasized. Any genetic testing?

I can say in my case, surgery was not an option. I was immediately started on ADT/ARSI (Orgovyx/Nubeqa) and will begin IMRT to the prostate in a couple of weeks. I'm a Gleason 9 (5+4) with lymph mets in pelvis, abdomen, and chest cavity along with spinal bone mets. No mention of chemo yet other than being possible in the future. Each case and each Dr is different so your path may be different as well.

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If you have five or less metastasis, then they can use SBRT radiation to zap them, And they would give you doublet therapy,. If you have more than 5 you usually have triplet therapy, which involves ADT, And ARSI (Zytiga or a lutamide) And chemotherapy or Pluvicto.

When there are more than five metastasis, there’s no treatment other than chemotherapy or Pluvicto, which can treat the whole body and hopefully greatly reduce the number of metastasis, And in some cases reduce them completely. I do know one person that had more than five metastasis zapped with SBRT, It required multiple sessions, that is unusual.

Here is some more information.

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