Prostate Artery Embolization (PAE) with PCa

I have never heard of this being used before. It is a useful treatment for BPH not for prostate cancer.

PAE works by reducing the blood flow to the prostate gland, which can lead to a decrease in prostate size and subsequently alleviate pressure on the urethra and bladder.

It's crucial to consult with a urologist or interventional radiologist to determine if PAE is an appropriate treatment option for your specific situation.

I had Tulsa Pro in Nov 2023, took out most of middle of prostate outside urethra which included lesions of PCa, but it left areas outside that. In July 2025 since I still had some BPH in that outer area that was left, I had PAE. So not the same as what is being proposed to you. You should look at Tulsa Pro, and my prostate was large but maybe you don't even need two procedures if your prostate isn't so large, maybe you just need Tulsa. I had it done in Sarasota, Dr Scionti, who has done more than just about anyone.

My PAE procedure was real easy. Tulsa Pro isn't hard either. Tulsa and PAE are safe and effective, Tulsa was heavily modified just before my Nov 2023 so it is much more effective. PAE is real easy to handle if you have a pro handling it. You won't find almost any urologist to comment positively on PAE, that is not their field. Dr Scioni is a urologist who handles Tulsa in Sarasota, but PAE is done by interventional radiologists usually and I had that locally. I don't have any ED from either procedure, Tulsa did not give ED, and PAE did not give ED.

My husband is having his PAE tomorrow by our RI. We previously have seen a urologist at Moffitt. They were perfectly happy with him having this procedure for his enlarged prostate. They told us they have seen good results with it. His prostate is very large. I was against the TURP that his urologist suggested. Then I questioned urologist about the PAE he told him he was a good candidate for the procedure. His Gleeson was 6 so for now it is just Active Surveillance but they said it would not interfere if he needed treatment in the future..and Moffitt had his biopsy slides so I’m happy with our decision. The best thing we did was go to Moffitt and get a second opinion on his slides. I wish you well on your journey.

Great comments thanks. In need to look into Tulsa. Tell me about your diagnosis. I am 62 very healthy and active, PSA was at 4.5 in Feb 2025 but last check in July 2025 is went down to 3.2 which is confusing. MRI in April 2025 found PIRAD 5 lesson 2.2 cm in the transitional zone so inside the prostate between the two layers. May 13 core MRI guided biopsy found area of concern had 70% abnormal with only 5% of that 4 the rest 3, so 3+4=7. Followed up with CT w/contrast and PSMA PET no spread. ArteraAI says cancer is very low grade only giving a .7% chance on metastification in 10 years. MiraDx/Prostox test says I’m not a good candidate for SBRT (only IBRT) due to a 95% chance of having long term grade2 level toxicity and urinary issues, so I’m looking at other options.

Yes, I had all my testing and diagnosis with Advent, but have also been to Moffitt and they did a 2nd opinion of my biopsy slides and had the exact same results as Advent so I’m happy with that. Also have visited with Mayo in Jax. I have a meeting next week with Dr. Nainesh Parikh at Moffitt who is a leader in PAE. His videos talk about advantages of PAE. My prostate isn’t that large, 41 ml, but I would say my urinary issues before any treatment is about a 3-4 on a scale of 1-10. This is one of the reasons I want to get PAE. My hope is also that it reduces my tumor size slightly which Dr. Nainesh Parikh said he’s observed. Not enough to kill the cells but it has shown it may shrink the lesion.

In 2021 after Pirads 5 MRI, I had a 3+4 (less than 5% was 4) that slides regraded by Hopkins said just 3+3, and 4 was not apparent. I spent next two years taking supplements to see if it helps. But in 2023 at Mayo MRI the lesion was smaller or tiny now, but on biopsy the 3 was gone and just the small 4 was left, making mine a tiny 4+4. So worse grading than yours technically but anyway it was a 3+4 that supplements killed the 3.

Tulsa Pro easily reaches transition zones.

Here is my long story
https://connect.mayoclinic.org/discussion/tulsa-pro-initial-experience/
which got many replies over 2 years, but my info is in there.

That makes sense to me. That was one of my questions for the IR tomorrow, whether there’s a chance as the prostate shrinks if there will be an effect on the Ca cells. Do they die, become dormant or does it not affect them?? Shrinking the lesion is welcome!
I’m a retired RN but this is way out of my specialty, so I’m learning so many things from everyone here. Not to mention a totally new language. In our lives. I appreciate you all. We went to Tampa because I didn’t care for the urologist’s explanation of atypical cells. Moffitt changed his diagnosis from the previous pathologist’s of atypical to cancer. So now we are testing more freq. so it was worth the trip.

Wow can you please share the supplements.

Watch this video. They talk about a reduction and in some cases the complete elimination of the cancerous tumor after PAE. Essentially stopping blood flow to it stops its growth and in some cases kills it. I wouldn’t rely on this but it can’t hurt in my situation.

Can't guarantee my links below, some links may not still be available.

Don't take all of these each day, just find ones you like, I did rotations but these were the ones I would say I like:
Boron
Lycopene/Tomato
Neem and Ginger
Crinum Latifolium
CLA and Modified citrus pectin
Iodine
Boswellia
Also take some NAC for your liver

Boron - 6 mg, liquid
Boron Reduces Prostate Cancer Risk
Nothing Boring About Boron
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/
"has demonstrated preventive and therapeutic effects in a number of cancers, such as prostate, cervical, and lung cancers, and multiple and non-Hodgkin’s lymphoma"
Dietary boron intake and prostate cancer risk
https://pubmed.ncbi.nlm.nih.gov/15010890/
Lycopene, 20 mg
The Potential Role of Lycopene for the Prevention and Therapy of Prostate Cancer: From Molecular Mechanisms to Clinical Evidence
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742263/
Lycopene effects contributing to prostate health
https://pubmed.ncbi.nlm.nih.gov/20155615/
Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review
https://www.nature.com/articles/pcan200938
Neem, Ginger
Ginger
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426621/
https://onlinelibrary.wiley.com/doi/abs/10.1002/jbt.22611
Neem
Neem components as potential agents for cancer prevention and treatment
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734358/
Consumption of a bioactive compound from Neem plant could significantly suppress development of prostate cancer

Crinum Latifolium
Crinum Latifolium Leave Extracts Suppress Immune Activation Cascades in Peripheral Blood Mononuclear Cells and Proliferation of Prostate Tumor Cells:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134856/
CLA and modified citrus pectin
https://pubmed.ncbi.nlm.nih.gov/14976130/
Both discussed:
https://www.lifeextension.com/magazine/1999/10/report4
Boswellia Serrata / Frankincense
https://aacrjournals.org/cancerres/article/68/4/1180/542608/Acetyl-Keto-Boswellic-Acid-Induces-Apoptosis
https://www.sciencedirect.com/science/article/abs/pii/S000629520800172X
Iodine (more advanced should use, not for everyone)
I don't have a thyroid (cancer) so I can take a fair amount or a lot, but don't do that if you have a thyroid, just a slight amount over RDA.
The Link Between Prostate Cancer and Iodine
https://www.biowarriornutrition.com/blogs/blog-page/the-link-between-prostate-cancer-and-iodine
A prospective study of iodine status, thyroid function, and prostate cancer risk: follow-up of the First National Health and Nutrition Examination Survey
https://pubmed.ncbi.nlm.nih.gov/17571964/
Iodine Uptake and Prostate Cancer in the TRAMP Mouse Model
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883964/
Just be aware the taking of iodine and not having good or adequate selenium levels is a known trigger to cause Hashimoto's disease. So that means if you choose to take iodine or more than RDA, have your primary care run a selenium lab first because if it is deficient that can cause a bad outcome.

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See also this guy who uses completely differing supplements and has some success, my supplements didn't ever lower PSA, I find ones that reduce PSA not great as they are often just like taking finasteride. Anyway, this person uses other supplements than I mentions above:
https://iloweredmypsa.com/