Hi, @drpepper and welcome to Connect. I was on xifaxan for over a year prior to my liver transplant and never had a belching problem. We are all different though in how medications affect us, and you are taking it for a totally different reason so your situation could be causing the belching.
I hope this is just temporary and will improve.
JK

I am on Xifaxan indefinetly after a colectomy which causes chronic SIBO. Have not experienced the belching.

@drpepper, here is some information on rifaximin (I apologize if this is repeat information or too generic), https://www.mayoclinic.org/drugs-supplements/rifaximin-oral-route/proper-use/drg-20065817. This does emphasize the point that any questions regarding dosing, how to take it, or taking things before, during, or after use or rifaximin should be discussed with your medical provider or pharmacist to get the safest, most accurate information. Have you discussed probiotics with your medical provider?

I had active MAC in 2015 and I was told to take probiotics and have been taking them ever since. I find my digestive system works much better with them.

Started 2 week regimen of rifaximin for SIBO. After 1st week belching much worse. Anyone else experience this? I'm hoping it a case of it gets worse before it gets better.

Thanks for input. I failed to clarify that I was taking rifaximin ro get rid of major excessive belching due to sibo and experienced an uptick in belching after first week. I have finished the 2 week regimen…belching better..wondering of I should start probiotics..

I take Align every day. I think it's controversial whether to take a probiotic after SIBO but for me, I feel and function much better. I'm also missing my right intestines due to a bowel obstruction. I take Xifaxan every day due to chronic SIBO.

Rifaxin