1. < Osteoporosis & Bone Health

Prescribed Evenity after 2 years on Tymlos.

Posted by mdm30 @mdm30, Mar 20 7:42pm

I am 65. I just finished 2 years of Tymlos and was given the option to try Evenity due to little improvement on Tymlos. I cannot find any research about this sequence of therapy meds. Has anyone found information on this or has anyone taken this course of treatment?

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mayblin | @mayblin | Mar 21 7:53am

Hi @mdm30 , was there any underlying cause(s) for the little improvement after a course of Tymlos?

Here is an important article published just a few months ago regarding anabolic to anabolic sequencing. Could be helpful to some of us:
https://academic.oup.com/jbmrplus/article/8/12/ziae131/7833424
At least one member on this forum did Forteo to Evenity with positive results after little improvement with Forteo. I also came across the rarer Evenity to Forteo/Tymlos sequence and read one person had success, not sure about others.

Please keep us posted!

REPLY
1 reply
mdm30 | @mdm30 | Mar 21 8:56am
In reply to @mayblin "Hi @mdm30 , was there any underlying cause(s) for the little improvement after a course of..." + (show)
@mayblin

Hi @mdm30 , was there any underlying cause(s) for the little improvement after a course of Tymlos?

Here is an important article published just a few months ago regarding anabolic to anabolic sequencing. Could be helpful to some of us:
https://academic.oup.com/jbmrplus/article/8/12/ziae131/7833424
At least one member on this forum did Forteo to Evenity with positive results after little improvement with Forteo. I also came across the rarer Evenity to Forteo/Tymlos sequence and read one person had success, not sure about others.

Please keep us posted!

Jump to this post

Mayblin, thank you for posting this article. I did read it and found it very informative. I had hoped that I could find an article/research on similar study with regards to Tymlos (Abaloparatide) to Evenity (Romosozumab).
I'll keep searching....

REPLY
1 reply
mayblin | @mayblin | Mar 21 10:14am
In reply to @mdm30 "Mayblin, thank you for posting this article. I did read it and found it very informative...." + (show)
@mdm30

Mayblin, thank you for posting this article. I did read it and found it very informative. I had hoped that I could find an article/research on similar study with regards to Tymlos (Abaloparatide) to Evenity (Romosozumab).
I'll keep searching....

Jump to this post

Agree, we shouldn't extrapolate findings from teriparatide 100% to abaloparatide. In the absence of good reviews on the particular sequence involving abaloparatide that you are looking for, this could be a good reference point as the two drugs act in a similar way although in general abaloparatide affects CTX less than teriparatide. Physicians' clinical experiences and anecdotal evidences could offer a great lead. Please share any information you are gathering and your decision. Best of luck to you!

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