Podcast Finding and Treating Inactive Breast Cancer Cells

Posted by colely @colely, Feb 8 5:35pm

On breastcancer.org, Dr. Angela DeMichele discusses The Clever Study. Fascinating. Extremely informative.

https://www.breastcancer.org/podcast/treating-inactive-breast-cancer-cells

Interested in more discussions like this? Go to the Breast Cancer Support Group.

Wow! Thank you for sharing this podcast info. It gives us hope that in the not too distant future there will be a way to find errant cancer cells that could still remain after treatment. I am very hopeful after listening to Dr. DeMichele's podcast! Many thanks for posting!❤️

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Incredible research going on! Wow!

Thank you for posting.

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@ssmab

Wow! Thank you for sharing this podcast info. It gives us hope that in the not too distant future there will be a way to find errant cancer cells that could still remain after treatment. I am very hopeful after listening to Dr. DeMichele's podcast! Many thanks for posting!❤️

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I missed this. Is there a way to hear this?

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@vtn

I missed this. Is there a way to hear this?

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Go to breastcancer.org and look for Podcast.

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@vtn

I missed this. Is there a way to hear this?

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I tried to post a link but I am not tech savvy and it didn't work. To find the podcast go to
breastcancer.org and touch the 3 bars at the top right. Then you will see a menu and Search is the last option. Touch that and enter "Dr. Angela DeMichele Podcast" in the search bar. It should pop up.

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@ssmab

I tried to post a link but I am not tech savvy and it didn't work. To find the podcast go to
breastcancer.org and touch the 3 bars at the top right. Then you will see a menu and Search is the last option. Touch that and enter "Dr. Angela DeMichele Podcast" in the search bar. It should pop up.

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Thanks for helping out! I wouldn't have known how to explain.

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@colely

Thanks for helping out! I wouldn't have known how to explain.

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@colleenyoung

I read the transcript after not absorbing the podcast! Hydroxychloroquine and Everolimus are the two drugs in the study, used separately or together, with an 80% rate of eliminating dormant cancer cells (found in bone marrow).

I was interested in the explanation that recurrence happens after 5 years for ER+ cancer, since cells don't wake up in that time. But for ER- they wake up earlier. That explains why risk goes up for ER+ after 5 years, but if you have ER_ you are pretty safe if you make it 5 years.

This really hit home:

"And I think this would really represent an important advance because up to this point surveillance has really been about watchful waiting, and I got into this because, you know, for gosh, 15 years I was taking care of patients and we’d get to the end of that initial treatment and they would say well, how do you know it worked, and what are we going to do now, and when am I having my scans? And I would say, look, I don’t really have a way to know that and I don’t really have a way to monitor you, and that’s very, very stressful for patients. "

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@windyshores

I read the transcript after not absorbing the podcast! Hydroxychloroquine and Everolimus are the two drugs in the study, used separately or together, with an 80% rate of eliminating dormant cancer cells (found in bone marrow).

I was interested in the explanation that recurrence happens after 5 years for ER+ cancer, since cells don't wake up in that time. But for ER- they wake up earlier. That explains why risk goes up for ER+ after 5 years, but if you have ER_ you are pretty safe if you make it 5 years.

This really hit home:

"And I think this would really represent an important advance because up to this point surveillance has really been about watchful waiting, and I got into this because, you know, for gosh, 15 years I was taking care of patients and we’d get to the end of that initial treatment and they would say well, how do you know it worked, and what are we going to do now, and when am I having my scans? And I would say, look, I don’t really have a way to know that and I don’t really have a way to monitor you, and that’s very, very stressful for patients. "

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Thank you for your help in explaining the information.

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@colleenyoung

Thanks.i finally found it. I wish these trials were for triple positive BC. The 2 mentioned are for ER+ HER2-.

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