Have you tried the new Protocol 525 product for neuropathy relief?

Posted by John, Volunteer Mentor @johnbishop, Apr 21, 2020

I have used the original version of the Protocol 525 product (https://theprotocolworks.com/) since 2016. I have idiopathic small fiber peripheral neuropathy with the only symptom being numbness in both legs. When I started taking the protocol, the numbness was just below my knees. After 2 months, the numbness seems to be just above the ankles which is subjective on my part with no additional testing. I do feel it is a win-win for me as my neuropathy has not progressed like I was told it would by the neurologist. I have continued taking the protocol in hopes that it may continue to roll back the numbness symptoms. I have noticed some new feeling in my feet in the last 2 months. Some feeling has returned to me feet and they seem to feel better lately although I still have the numbness – hard to describe the difference.

The Protocol 525 is not a cure for neuropathy. It treats the pain and discomfort symptoms of neuropathy without the drugs which have their own side effects. Have you tried the Protocol 525 or the original protocol? Did it help? If yes, how? If no, please share.

Note: I have no commercial investment in the protocol and I am sharing this information as someone who has found some degree of relief using this combination of supplements. I also discussed these supplements with my Mayo primary care team before I started taking them. The care team sent them to the pharmacist for review who did not have any major concerns for me taking them.

*** Edited Oct 3, 2023 ***
For more information and a list of the ingredients, please see the frequently asked questions on the Protocol's website here - https://theprotocolworks.com/faq/.

Interested in more discussions like this? Go to the Neuropathy Support Group.

janiern2 | @janiern2 | Jan 26 8:52pm

In reply to @jaddaj441 "The product is $193.00 a month? Am I looking at the right product?" + (show)

That’s unfortunate that they price this so high. I am glad it’s helping patients but it seems like they could make this more affordable.

cayman44 | @cayman44 | 1 day ago

In reply to @jaddaj441 "The product is $193.00 a month? Am I looking at the right product?" + (show)

If protocol 525 is a list of supplements, which are the ones you really need? Why do we have to pay $193 a month for a magical protocol? Has not Mayo looked at each supplement and have a recommendations. This is crazy!!!!!

John, Volunteer Mentor | @johnbishop | 1 day ago

In reply to @cayman44 "If protocol 525 is a list of supplements, which are the ones you really need? Why..." + (show)

@cayman44, Thought I would provide my two cents for your questions...

If protocol 525 is a list of supplements, which are the ones you really need?
----------------
Good question, I'm not a doctor and have no medical background but think it can depend on a lot of different factors, including any vitamin deficiencies that a person might have. The Foundation for Peripheral Neuropathy has a pretty comprehensive list which I think most of them are included in the protocol - https://www.foundationforpn.org/vitamins-and-supplements-for-nerve-health/.

Why do we have to pay $193 a month for a magical protocol?
-----------------
Simple answer, you don't. Nothing magical about supplements. Best to do your own research on each one. You can order them each separately if you choose. Not sure how much that would cost.

Has not Mayo looked at each supplement and have a recommendations. This is crazy!!!!!
-----------------
No, I don't believe Mayo Clinic has looked at each supplement and given recommendations. I have discussed the protocol supplements with my Mayo Clinic PCP and care team and they didn't have a problem with me taking it to see if it helps my neuropathy. It's OK that you think it's crazy but I started this discussion because it has helped me somewhat and I wanted to learn from the experience of others if it has also helped them.

I shared a document in another discussion that lists the supplements in the protocol along with links to the specific research related to how they help with neuropathy - https://connect.mayoclinic.org/comment/957496/.

pua0609 | @pua0609 | 1 day ago

I have peripheral neuropathy (numbness) in my feet, which has been getting worse through the period of 6 years. I do not have diabetes, but am borderline, according to lab results.
Thanks for any input.

Justin McClanahan, Moderator | @JustinMcClanahan | 1 day ago

In reply to @pua0609 "I have peripheral neuropathy (numbness) in my feet, which has been getting worse through the period..." + (show)

Hi @pua0609,

I combined your discussion with an existing discussion titled:

"Have you tried the new Protocol 525 product for neuropathy relief?"
- https://connect.mayoclinic.org/discussion/have-you-tried-the-new-protocol-525-product-for-neuropathy-relief/

@johnbishop started this conversation and many members have discussed it. While the discussion may be lengthy, it has many examples of members sharing their thoughts and experiences with protocol 525.

@pua0609 - is protocol 525 something you are considering trying or have discussed with your provider?

heisenberg34 | @heisenberg34 | 1 day ago

The Protocal seems like so many so-called neuropathy treatments. Many ingredients, expensive, must take forever(good for the company), and no offer of money-back options. I'll pass for now.

heisenberg34 | @heisenberg34 | 1 day ago

I tried to find reviews of Protocol 525, or The Protocol. Gave up after about ten minutes. Only the company's online customer reviews showed up. Not a reliable source.

pua0609 | @pua0609 | 21 hours ago

In reply to @JustinMcClanahan "Hi @pua0609, I combined your discussion with an existing discussion titled: "Have you tried the new..." + (show)

Thanks so much for the response. I just joined this group this morning. I have no knowledge about Protocol 525. Am curious as to what exactly it is, and would really like more info. Any suggestions?

pua0609 | @pua0609 | 21 hours ago

In reply to @JustinMcClanahan "Hi @pua0609, I combined your discussion with an existing discussion titled: "Have you tried the new..." + (show)

Hi JustinMcClanahan,

Thanks for getting back to me so quickly. I'm trying to find out what
Protocol 525 is. I just joined the Mayo Group this morning and read
someone's message about this supplement.

I need to know more before considering taking it.

Appreciate feedback.

pua0609

John, Volunteer Mentor | @johnbishop | 20 hours ago

In reply to @pua0609 "Thanks so much for the response. I just joined this group this morning. I have no..." + (show)

Hello @pua0609, I shared a document in another discussion that lists the supplements in the protocol along with links to the specific research related to how they help with neuropathy - https://connect.mayoclinic.org/comment/957496/. It's no longer called the Protocol 525 which actually stood for 5 capsules in the morning, 2 at noon and 5 in the evening. Now they have combined some of the supplements into fewer capsules so we only take 4 morning, 2 noon and 4 evening. They have a frequently asked questions page on their site here - https://theprotocolworks.com/faq//