Physical Therapy while Rebonding from Prolia

@sbax75 according to all my sources (including McCormick's "Great Bones" and Leder's YouTube video "Combinations and Sequencing Approaches to Osteoporosis" Tymlos is not effective after Prolia and you need Reclast or Fosamax to combat rebound. Some posters lately have shared studies on Evenity after Prolia, so maybe you could ask your doctor about that.

My PT does massage only, to address muscle spasms from fractures.

Tymlos will make the fracture heal more quickly.

The problem with Prolia is that it stops preosteoclasts in their final phase. These preosteoclasts collect in what the call reservoirs of cells that mature quickly and attack the bone when you stop Prolia.
I'd wish you could take a low dose of Reclast with the the Tymlos. Sometimes we can't take an "optimal" path.
Still, you may weather this with Tymlos.
Will your provider prescribe bone markers? Could you insist? That way you would be better apprised of your bones reaction to the medication and could alter course, if necessary.
You need a really good physical therapist who will prescribe low level impact. I think the physical therapist who understand osteoporosis are rare. You may have to refuse stressful exercise for six months or until your bone markers show a balance.
I'll be very interested in your path.

@gently my doctors and resources say Tymlos does not work after Prolia. Based on that, this course seems risky. You are very well-informed so maybe you could share a resource that says Tymlos is okay after Prolia. This is relevant for me and all of us.

windyshores, these anabolics are not optimal after Prolia. I've read speculation that Evenity is also not a good option, the speculation being that the while Evenity halts the differentiation of cells into osteoclasts, the preosteoclastic cells delayed by Prolia are past that initial stage.
There may be a reason (unknown to us) in a person's medical history that would preclude the use of bisphosphonates.
Sometimes we take the only path available.
Second opinions are significant for the medically underserved. But what can you do meanwhile, if meanwhile is a year.

@gently and @sbax74 it seems Evenity might be a better choice, pending more research- but at least one study posted here said it had effectiveness, if limited, after Prolia. Not sure what the reaction was to bisphosphonates but another possibility is low dose with one hour hydration and one hour infusion. Of course your doctor is a better resource, I hope, than this forum!

windyshores,
Reclast is the best choice. Evenity is probably a better choice than Tymlos. At least studies of rotating between Prolia and Evenity have been deemed successful.
This connector is not offered a choice or even a consultation and can't get a consultation for another year.
Windyshores is the best resource on this forum and anywhere else.

@gently unfortunately @sbax74 wrote they had a "bad reaction to bisphosphonates" so I think you are right about Evenity...but after Evenity things will continue to be complicated if bisphosphonates aren't possible!

We are all between a rock and a hard place! You are a great resource on this forum as well 🙂