P1NP after 1-3 months Evenity

Posted by aspirecreative @aspirecreative, 2 days ago

Hello, I had read that it is good to check P1NP 1-3 months after Evenity, but my Endo says no, it is not helpful to check. Welcome any info about this. Thank you.

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njx58 | @njx58 | 2 days ago

Supposedly P1NP peaks very early with Evenity, so at this point, it may not be helpful.

Here is an older thread that you will find helpful.
https://connect.mayoclinic.org/discussion/evenity-and-bone-markers/

tshcpa | @tshcpa | 2 days ago

I checked mine 6 weeks after 1st Evenity shot. My P1NP was 82 before Evenity and went up to 232 at the 6 week mark. The spike in P1NP can tell you if Evenity is working from what I understand, but it does peak early on. I only ended up taking 3 shots of Evenity due to issues with it, but I had 10% gain in the bone density of my spine.

aspirecreative | @aspirecreative | 1 day ago

@tshcpa, What did you go on after the Evenity? Thank you.

tshcpa | @tshcpa | 1 day ago

In reply to @aspirecreative "@tshcpa, What did you go on after the Evenity? Thank you." + (show)

I am taking Alendronate (Fosamax) weekly, and I plan to take it for 1 year. I will recheck my bone markets and have a DEXA 6 months after stopping the Alendronate to determine the next course of action. At that time, I may take a drug holiday, continue Alendronate, or take Tymlos to build more bone. I am consulting with Dr. McCormick and I am primarily following his guidance so far.
My TBS was normal (1.313) before starting Evenity, and it increased 5% during the 3 months, so now it is above normal (1.383). My spine was -3.3 before Evenity and is now -2.6. I am one of those who had never taken any drug prior to Evenity.