Oxaliplatin is no walk in the park, advice for CAPOX regimen?

Thank you for this and for following up.
He has completed 4 rounds of 5FU and honestly he is doing well. His main side effect is the cold sensitivity. He does wear gloves when he has to go into the refrigerator, but I try and take everything out for him beforehand. Hopefully as the weather gets warmer he will feel better. We go for treatment next week and will share this information with the Oncology team.

Welcome, @jd1010. Your questions about the cold packs are good ones. I'm tagging @roywalton to make sure he sees your questions.

JD, the cooling mitts and socks are worn during chemotherapy infusion. You might find this article helpful:
- Can Cooling Gloves and Socks Relieve Chemotherapy Neuropathy? https://www.healthline.com/health/cancer/can-cooling-gloves-and-socks-relieve-chemotherapy-neuropathy

Here's a related discussion:
- Chemo cold cap, socks and mitts: Share your experiences
https://connect.mayoclinic.org/discussion/chemo-cold-cap/
How is your husband doing?

I sure wish I would have known that 10 years ago after infusions with Oxaliplatin. The nerve damage seems to be from the weakness in the hip, knee buckling, foot drop and now hammertoes on my right side. It's hard to believe that the drugs we have to take to save our lives
can do such damage.

I did ice packs and drank ice water during my infusions. It helped with that jaw tightening when drinking. My oncologist also added Emend to my premeds to help with the horrible nausea

The Capecitabine pills are just as rough as the Oxaliplatin. 5FU in this fashion is deemed tougher than the 5FU thru the port... but can be a more effective cancer killer. The cold capping for hair loss is useless (from all that I have talked to)... besides, hair grows back soon enough when done with treatments. But the cold gloves and socks have helped many that I have talked to by lessening neuropathy. Some just hold frozen plastic water bottles during the Oxaliplatin infusions.

Gary

Again. Only wrap during the infusion of oxaliplatin. The cold temp shuts down the capillaries in toes and finger so less oxaliplatin "leaches" in surrounding tissues. This is what causes the issues. Hop this helps you....worth trying!

I wish I had known that when I had my chemo last year! Good to know moving forward.

No kidding! After the first infusion I reached for a pitcher the refrigerator and it felt like I was grabbing stainless steel at -20°.

The cold sensitivity got better but still dealing with very minor neuropathy in the left foot, 4 months after last infusion. Btw if you get palmer plantar skin peeling the product Urea 40 on Amazon worked the best! Has aspirin in it along with urea and it worked well

Oh thank you I will ask them next time.

This sounds like the same idea as how the cold caps work for hair?

Yes more cold After infusion would just send the pain to the moon lol

Hi - My husband is really affected by the cold sensitivity. Just wanted more on the cold packs... you applied them to your fingertips and toes after the infusion? For how long and for how many days? Appreciate the tip. Thanks!