Nano Knife

Posted by cole5055 @cole5055, 2 hours ago

Hello All,

After fighting with the VA for three years ( 100% Disabled Desert Storm 20yrs 🇺🇸 ) I finally made it to Mayo Phoenix 😊 What a difference dealing with true professionals!

After completing my Trans-Perineal Targeted MRI Fusion biopsy 3+4 all contained in the prostrate 🙏 my Doctor recommended Nano Knife, it had just became available in 2024 and is still considered experimental. It seems to have the least side effects and I do not need ADT what a relief. My nurse informed me that they have treated over 300 patients with very good results!

My question? If you have had the Nano knife treatment please chime in and share your experience 🙏 it would be most appreciated 😊

Most Respectfully
Ray & Lucy 🇺🇸

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

NanoKnife is focal therapy. Here’s the opinion of a well respected radiation oncologist about that. It may work just fine for you. It may not. Ask for the reoccurrence statistics from your doctor.

You should get a decipher test, which can tell whether or not there’s a chance of reoccurrence with your prostate cancer diagnosis.

At the 11/1/2025 PCRI conference the following was said by Matthew R. Cooperberg, MD, MPH

What about focal therapy?
* The energy modality matters much less than the accuracy of the imaging - which is not there yet.
* Overall focal therapy is associated with minor side effects, but high rates of recurrence both in- and out-of-field.
* Focal therapy is not really a replacement for surgery or radiation; it is better considered an adjunct to active surveillance

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