My T 3, T4 & TSH have been tested,all normal, thyroidectomy?

Posted by reen88 @reen88, Jun 20, 2023

Here is my question, getting total thyroidectomy with lymph nodes removed. I understand I have many nodules, largest 5 cm going into my chest cavity. My blood work also came back normal. So….this pill I will need for the rest of my life needs to be regulated……how if my blood work won’t show problems as it did in the past??

Interested in more discussions like this? Go to the Thyroid Cancer Support Group.

Sorry, finish question…so how do they regulate my body for this new drug I’ll be taking?

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I had a large nodule which after removal was diagnosed as Hurthle Cell Carcinoma. My blood work was always fine. It is not that the test did not identify the problem, it was that the problem (cancerous nodule) did not cause my thyroid to malfunction.
I had a lobectomy so I have half a thyroid and am having difficulty getting regulated on Synthroid, however I think this is typical for anyone going on medicine. It takes about 6-8 weeks after staring the medication to see if it brings your thyroid into the “normal range.” Unfortunately, the “normal range” is based on the typical range and might not coincide with what your body’s “normal range” is. Any changes in dose takes about 6-8 weeks to see in blood work and the weird symptoms of problems are difficult to identify as directly related to thyroid/medications.
Right now, my thyroid blood tests are in the normal range but I am having issues which appear to indicate that this range is not MY appropriate level. I am amazed at how hard it is to get this balanced!

In my opinion, it is helpful to read the side effects of thyroid disease and write down your medication and your dose, along with any episodes that MIGHT be related to thyroid. Just because your numbers are in the normal range, you might be having symptoms with that range so a change in medication might help eliminate the problems.
I recently looked back at old blood test to see what my TSH and T4 numbers were to get an idea about where my typical levels were. Although removing the thyroid/lobe might change this, I thought it might help to see if the symptoms decrease when I am closer to my prelobectomy levels. As of now, I my TSH and T4 are higher than what I had “typically” been prior to surgery. My doctor just added a mini dose increase (half a tablet) to see if eliminates the negative side effects…I am hopeful that things improve.

I think getting regulated on Synthroid is a process that is complicated by the random issues that present; and the fact that the issues may/may not be related to Synthroid dose.

One last comment….I chose Synthroid instead of the generic because it is more consistent in its levels. Generic medications can vary by manufacturer and since I already have a history of having problems with medication side effects, I decided it was best to eliminate the variable that is associated with generic medication. Some people do better with the generic versions so it is not that I won’t try this if things don’t improve, however to start with, I went with Synthroid.
Good luck!

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Oh thank you koh. I appreciate you taking the time to share. I just found out something in the blood they tested for that I don’t think I ever had that checked. Thyroglobulin is 490. According to the normal range, should be 1.6-59.9 ng/ml. So evidently my blood work is not normal like I thought. Guess we will see. If I get to choose my meds, I will try synthesis. Thanks so much again!

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@reen88

Oh thank you koh. I appreciate you taking the time to share. I just found out something in the blood they tested for that I don’t think I ever had that checked. Thyroglobulin is 490. According to the normal range, should be 1.6-59.9 ng/ml. So evidently my blood work is not normal like I thought. Guess we will see. If I get to choose my meds, I will try synthesis. Thanks so much again!

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@reen88 … I was told that the thyroglobulin is a tumor marker. Once you have thyroidectomy or lobectomy the number should go down and then they monitor the level to help determine if there is growth.
I am still trying to get a better understanding about “thyroglobulin antibodies” which is also monitored. Mine has been going up but I don’t understand the relationship between the thyroglobulin and thyroglobulin antibodies.

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