My Journey....

Posted by casd57 @casd57, Oct 7, 2023

So far three Biopies, the last one was MRI-guided
No cancer but PSA is rising I just went for blood work yesterday and we will see if it has risen since 1/23 PSA 15.7
I'm getting ready for Testosterone shots due to my number being in the normal but low range..259
I'm going into it with caution and doing blood work every 3 months and also watching any urination changes (large prostate already)
I'm posting this and going to post my journey as I do this and keep an eye on my Prostate
Oh....I had Thyroid cancer 1997 and my Thyroid was removed ..So I feel I have the cancer gene if there is one..

From my Chart:
Impression
1. Mild BPH.
2. Suspicious abnormality along the right apical posteriorly and and medially. Abnormality extends near the neurovascular bundle.

PI-RADS 4 - High (clinically significant cancer is likely to be present)
Narrative
HISTORY: Rising PSA. Negative prostate biopsy 2013 and 2022. History of benign prostatic hypertrophy with urinary obstruction. Erectile dysfunction.

PSA: 10.6 ng/mL, March 21, 2022
12.8 ng/mL, September 29, 2022
15.7 ng/mL, January 13, 2023
Biopsy: Negative prostate biopsies in 2013 and 2022
Prior Therapy: No prior therapy.

TECHNIQUE: 20 mL of MultiHance was injected intravenously. Precontrast and postcontrast multiplanar and multisequence 3.0T MRI imaging of the pelvis was performed with focus on the prostate in accordance with ACR PI-RADS recommendations.
3D segmentation and kinetic analysis of the prostate gland was performed on a separate workstation by a radiologist utilizing DynaCAD software.
Endorectal Coil: No

From Mychart 4/2023 MRI-guided Biopies results
FINAL DIAGNOSIS
View trends
A. PROSTATE, RIGHT BASE, NEEDLE CORE BIOPSIES:
BENIGN PROSTATIC PARENCHYMA.

B. PROSTATE, RIGHT MID, NEEDLE CORE BIOPSIES:
BENIGN PROSTATIC PARENCHYMA.

C. PROSTATE, RIGHT APEX, NEEDLE CORE BIOPSIES:
BENIGN PROSTATIC PARENCHYMA.

D. PROSTATE, LEFT BASE, NEEDLE CORE BIOPSIES:
BENIGN PROSTATIC PARENCHYMA.

E. PROSTATE, LEFT MID, NEEDLE CORE BIOPSIES:
BENIGN PROSTATIC PARENCHYMA.

F. PROSTATE, LEFT APEX, NEEDLE CORE BIOPSIES:
BENIGN PROSTATIC PARENCHYMA.

G. PROSTATE, LESION #1, NEEDLE CORE BIOPSIES:
BENIGN PROSTATIC PARENCHYMA.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Obviously the rising PSA is concerning but I've read that BPH can cause that to happen along with the other things discussed on this forum, sex, certain exercise etc..

The PI-RADS 4 can have false positives from nodular hyperplasia which sounds like what might be going on with the findings from the #2 above when combined with the negative findings on the biopsy. Maybe you're one of the luckier ones!

Sounds to me like you're doing everything you can to keep an eye on the situation by getting the regular blood work while you and your team watch the situation.

I'd say for now, take the win!!
Best of luck going forward!

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@casd57, If your PSA is increasing and your PI-RADS 4 – High (clinically significant cancer is likely to be present) why would you have Testosterone shots, to feed the prostate cancer?

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Good question, I'm asking myself the same thing, probably because no cancer has been found with 3 biopsies and the last one was a MRI guided.
Got my PSA test back 16.5
Did some digging and see my AC1 is 5.6. As of August Glucose 145. As of june

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