My Gleason score is 7 - 3+4. How long can I live without treatment?

Posted by mayoclinicadvice23 @mayoclinicadvice23, Jun 11, 2023

My Gleason score is 7 - 3+4,. How long can I live without treatment? Since I decided not to get any treatment, because of horrible side effects, I was wondering, if someone who experienced the same condition, will share his experience with me.

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@villageidiot

I'm 55 with a 1.2mm lesion and just got biopsy result with nearly half the cores Gleason 3+4 throughout much of the prostate. Recent PSA was just over then just below 4, with nothing to reference for several years before that. Still waiting to see the doctor, but preparing for the hard sell on removal. Like @cianci I'm curious what your other numbers where like, and how they've progressed over the years.

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I'm tagging @hunter1877 to make sure he sees the questions from you and @cianci.

@villageidiot, have you made your treatment decision? How are you doing?

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Had prostate removed in 2010 with Gleason score of 8. Radiation follow-up of prostate bed. At 82 age just starting treatment for bone metastasis. No reoccurrence for almost 15 years. Hopeful for success with current treatment's plan.

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@pieperfarm

I was confirmed to have Gleason 6 in 2017, and Gleason 7 in 2023. I had a HIFU procedure with no side effects to eliminate all of the Gleason 6 and Gleason 7 in 2024 on one side of the prostate. I still have Gleason 6 on the other side of the prostate. I am 58.

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Did they not do the other side because it was anterior (too far for HIFU). That was my situation, so I then sought out Tulsa Pro. I was treated in July for Gleason 7 at Mayo. No sign of cancer at 6 months.

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@graybeard46

I asked this question after I had surgery, Dr can’t really give you a good answer, how old are you ? I ask myself this question but it’s too late surgery missed getting it all now into radiation, asked my radiologist that question last week but now my cancer more active than originally know so he said maybe 5 yrs as a guess, good luck if you about 70 it’s a gamble on your part, good luck

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No one has a crystal ball. 5 yrs, 10 yrs, it’s all guesswork. Really surprised your doctor put ANY time frame on your possible lifespan. You are currently in salvage radiation with ADT - far, far, FAR from being anywhere near dead from PCa!!
There are guys on this board who got this disease in their 50’s and early 60’s who are still here in their 80’s so where’s this 5 yr BS coming from??
It’s cold and bleak in the Boston area this time of year, but in about 2 months things will start to green up, you’ll be done with radiation and you’ll feel a lot better about things. Just give it time…
Phil

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@heavyphil

Sounds like you have a plan. Didn’t know you had a short life expectancy so perhaps this non- treatment works best for you.
Phil

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Just to clarify: not "short life expectancy", but "acceptably good more years left". After those 5 years, at then 83 years old, I expect -- though of course hope I'm wrong! -- my current lifestyle will have to change for reasons other than PCa.

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I asked this question after I had surgery, Dr can’t really give you a good answer, how old are you ? I ask myself this question but it’s too late surgery missed getting it all now into radiation, asked my radiologist that question last week but now my cancer more active than originally know so he said maybe 5 yrs as a guess, good luck if you about 70 it’s a gamble on your part, good luck

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I was confirmed to have Gleason 6 in 2017, and Gleason 7 in 2023. I had a HIFU procedure with no side effects to eliminate all of the Gleason 6 and Gleason 7 in 2024 on one side of the prostate. I still have Gleason 6 on the other side of the prostate. I am 58.

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@joecontheroad

The "just had" is not comforting: it's the sometime after just had that I am concerned about and what prevents my doing it. BTW: that "rise", for now at least, is only to 0.08 (from < 0.05, but psa's from two different labs, and the newer one is not known to me as wholly reliable) while off of ADT for 9(?) months. And, it seems to me, I don't likely have more than five acceptably good more years left anyway, and if going back on ADT keeps things in check for those years... 😉

I've provided this link in response to a post elsewhere. It was published after I had made my decisions, so it *maybe* has confirmed my decisions rather than having influenced them:
https://www.urotoday.com/video-lectures/localized-prostate-cancer/video/4525-overtreatment-of-prostate-cancer-persists-in-men-with-limited-life-expectancy-timothy-daskivich.html

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Sounds like you have a plan. Didn’t know you had a short life expectancy so perhaps this non- treatment works best for you.
Phil

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@heavyphil

Can I ask why no radiation? I just had 25 rounds at Sloan and it was nothing. The worst ( if I can even call it that!) part is figuring out the bladder and bowel prep. Side effects minimal.
Sure, maybe years out they will develop, but I might not have gotten those years without the treatment.
Being on ADT for the rest of your life - which rising PSA indicates- can possibly be even more hazardous to your health.
Not criticizing or judging your personal decisions. Mine are different, that’s all. You’ve really been quite fortunate to go 20 yrs without treatment and no one can deny that the gamble you took really paid off.
Best of luck on whatever you decide!
Phil

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The "just had" is not comforting: it's the sometime after just had that I am concerned about and what prevents my doing it. BTW: that "rise", for now at least, is only to 0.08 (from < 0.05, but psa's from two different labs, and the newer one is not known to me as wholly reliable) while off of ADT for 9(?) months. And, it seems to me, I don't likely have more than five acceptably good more years left anyway, and if going back on ADT keeps things in check for those years... 😉

I've provided this link in response to a post elsewhere. It was published after I had made my decisions, so it *maybe* has confirmed my decisions rather than having influenced them:
https://www.urotoday.com/video-lectures/localized-prostate-cancer/video/4525-overtreatment-of-prostate-cancer-persists-in-men-with-limited-life-expectancy-timothy-daskivich.html

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@chippydoo

Thank you and wish I had this prior to starting short term Lupron for 6 months. Going to ask if I can switch at my 3 month appointment and shot. Frankly I am at the point of switching Doctors. Every week something else like this pops up. Best wishes.

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I don't think that is uncommon - (every week something else pops up.)

Might mention that if you download the Supplementary Appendix from the link provided in the paper there is a lot of other detailed comparison data. FYI.

Best of luck!

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