My Gleason score is 7 - 3+4. How long can I live without treatment?

That seems like a lot of treatment for a 3+4 Gleason, but I'm new to this message board
I recently had a parametric MRI that showed PIRADS 4 and a 12mm lesion, also a 95 on the 4K score I am having a fusion biopsy in a week. I am 70 years old, and I will not consider surgery, unless Gleason 8 +
My Dad had PC at age 63, had a Radical Perineal Prostatectomy in 1984, much different than today, with advanced techniques. It left him impotent for the rest of his life. He was treated at Mayo, they also did an orchiectomy ( removal of testicles) and put him on Casodex? and other hormone blocking drugs. They did not get all the cancer with the RP and it eventually spread to the bone, but he was 90 years old at that time, and he actually died from a sepsis infection. The hospital doctor and my Dad decided not to treat, considering that bone cancer death would have been more painful and drawn out. My Dad was always cheerful, had 65 people at his 90th birthday party, played golf until age 87, and generally enjoyed life. I don't think I would be as resilient

I was a 7 (3+4) April 2021 and had the robotic surgery. They took out everything. Three of eleven lymph nodes they also removed tested +, so fall 2021 I had seven weeks of radiation, and Luprin (sp.?) shots every six months. So far, bone scans are clear and my blood tests measure 0. But the effects of no testosterone start off subtly but become significant—low energy, no sex drive, immense depression. Lesson: you can survive the treatment, but can you survive the recovery? I struggle emotionally and physically daily. Not sure I’d go through it again.

I've sent a PM response.

Because the first score indicates the most common grade of cell in the sample, a 4+3 moves you from intermediate favorable to intermediate unfavorable, a change that would lead most clinicians to recommend against active surveillance, leaving you to consider more immediate treatment options. Generally the recommendation in this range begins with radical prostatectomy, because you have significant cancer in the prostate, but a good chance of removing the existing cancer before it spreads beyond the prostate.
However, since a good number of clients do not like RP, there are other treatment options, most of which involve ablation--killing the cancer in place, with radiation or some other strategy. Radiation is not really clinically preferable, so the search continues for something better than both existing forms of ablation and existing forms of RP.
[I've tried to be fair and inclusive here, but emotions do run high among clients, and ambitions to do better run high among clinicians.]

Gleason scores are assigned to biopsy results and they are reported as 2 numbers.
The first number being the most prevalent cancer grade and the second number being the second most prevalent cancer grade.

So 3 + 3 equals Gleason 6
3 + 4 = 7
4 + 3 = 7, but indicates more aggressive cancer because the predominant cancer found was a Gleason 4.

My final postop biopsy results were Gleason grade 9 ( 4+ 5).
I also had a number of Gleason 8s (4 + 4).

Prostate Cancer is graded on your highest score, so I am considered a Gleason 9, which is in the aggressive category 8 - 10.

Best wishes,and I hope that this is helpful.

2 cores. Active surveillance is keeping you from treatment when you could be really needing it. prior to proton therapy my urologist ran a test and told me you have a one percent of still being here at 10 years and so I went for the therapy and my PSA keeps dropping and I know I have beat it.

I have a 3+4 and a 4+3 what does it mean?

Just make sure your Gleason IS 3 + 4...and NOT 4 + 3...there is a difference!

I too had a Gleason 3+4=7. I opted for removal in early December. My pathology report confirmed the 3+4=7 and showed negative margins and no spread elsewhere so I'm optimistic. The pathology did show, however, perineural invasion (PNI) was present which reinforced for me that I made the right decision for removal. Based on my research PNI is the pathway for spreading so I'm very glad it's out vs. going on AS. This was only found on the whole gland pathology, not the biopsy.
As for side effects, everyone is different, but you can ask your surgeon whether they think you are a candidate for nerve sparing (ED) and the hood technique for reconstruction of the urethral complex (incontinence) as these can lead to more successful outcomes with respect to side effects. Here's a link to some info on the hood technique (https://pubmed.ncbi.nlm.nih.gov/33067016/).

Best of luck on your decision, it's certainly not an easy one!

After my biopsy, I also had a Gleason score of 3+4=7 in two cores out of 14. After doing some research and talking with RP patients and 2 surgeons, I chose removal, which occurred in November. My pathology report came back with an actual Gleason score of 4+5=9. My post-PSA just came back recently at < 0.01. Hoping for more of the same in the future. My point is this: take whatever steps necessary to make sure your Gleason score is accurate. Otherwise, know your treatment options. BTW, my surgery went very well and I had NO incontinence issues. I did Kegel exercises religiously. Best of luck!