My Gleason score is 7 - 3+4. How long can I live without treatment?

Dear MitchM and Ranger44,
Of Course, you can and will be resilient and survive, even thrive, in our new life! Don't let the trials of PC, Winter Doldrums, our National Politics and Our Warring World completely drain your souls from the joys and wonders of Life! I'm appreciative of both of you posting your thoughts and feelings. As my father would say to all of his 12 children at the dinner table, "It's never as good as it looks or as bad as it seems." We live in the Greatest of Nations, at one of the greatest times in His/Herstory. The BEST for the World is yet to come with Our American Ideals, Industrialness and Optimism! Stay Strong My Brothers, the Future Looks BRIGHT! God Bless you both and all in the World.

Agree with other post. Maybe more to it. 3+4 without other important factors likely would not require that much treatment. Best to you going forward.

My Gleason is also 3+4= 7 with MRI, biopsies, and PSMA prior to starting treatment (ADT) in August, 2023. Did Casodex for 30 days and had my first Bupron P injection. The first 2.5 months were dreadful: no energy, hot flashes, weight gain, loss of libido, and more. Then, for whatever reason, all those symptoms dissipated. I had my second injection, being on the 3-month regimen, without the symptoms returning. My 3-month blood test revealed a testosterone level of 10 and a PSA of 0.05. My urologist wants it to be undetectable, so will have my second blood draw mid-February when I will also have my third injection. Since Bupron is time release, I attributed the symptom decrease to that as the 3 months were coming to an end, but the fact that they did not return with the second injection was very encouraging. Go figure, but it underlies the fact that none of us will react the same to the many treatment options now available.

That seems like a lot of treatment for a 3+4 Gleason, but I'm new to this message board
I recently had a parametric MRI that showed PIRADS 4 and a 12mm lesion, also a 95 on the 4K score I am having a fusion biopsy in a week. I am 70 years old, and I will not consider surgery, unless Gleason 8 +
My Dad had PC at age 63, had a Radical Perineal Prostatectomy in 1984, much different than today, with advanced techniques. It left him impotent for the rest of his life. He was treated at Mayo, they also did an orchiectomy ( removal of testicles) and put him on Casodex? and other hormone blocking drugs. They did not get all the cancer with the RP and it eventually spread to the bone, but he was 90 years old at that time, and he actually died from a sepsis infection. The hospital doctor and my Dad decided not to treat, considering that bone cancer death would have been more painful and drawn out. My Dad was always cheerful, had 65 people at his 90th birthday party, played golf until age 87, and generally enjoyed life. I don't think I would be as resilient

I was a 7 (3+4) April 2021 and had the robotic surgery. They took out everything. Three of eleven lymph nodes they also removed tested +, so fall 2021 I had seven weeks of radiation, and Luprin (sp.?) shots every six months. So far, bone scans are clear and my blood tests measure 0. But the effects of no testosterone start off subtly but become significant—low energy, no sex drive, immense depression. Lesson: you can survive the treatment, but can you survive the recovery? I struggle emotionally and physically daily. Not sure I’d go through it again.

I've sent a PM response.

Because the first score indicates the most common grade of cell in the sample, a 4+3 moves you from intermediate favorable to intermediate unfavorable, a change that would lead most clinicians to recommend against active surveillance, leaving you to consider more immediate treatment options. Generally the recommendation in this range begins with radical prostatectomy, because you have significant cancer in the prostate, but a good chance of removing the existing cancer before it spreads beyond the prostate.
However, since a good number of clients do not like RP, there are other treatment options, most of which involve ablation--killing the cancer in place, with radiation or some other strategy. Radiation is not really clinically preferable, so the search continues for something better than both existing forms of ablation and existing forms of RP.
[I've tried to be fair and inclusive here, but emotions do run high among clients, and ambitions to do better run high among clinicians.]

Gleason scores are assigned to biopsy results and they are reported as 2 numbers.
The first number being the most prevalent cancer grade and the second number being the second most prevalent cancer grade.

So 3 + 3 equals Gleason 6
3 + 4 = 7
4 + 3 = 7, but indicates more aggressive cancer because the predominant cancer found was a Gleason 4.

My final postop biopsy results were Gleason grade 9 ( 4+ 5).
I also had a number of Gleason 8s (4 + 4).

Prostate Cancer is graded on your highest score, so I am considered a Gleason 9, which is in the aggressive category 8 - 10.

Best wishes,and I hope that this is helpful.

2 cores. Active surveillance is keeping you from treatment when you could be really needing it. prior to proton therapy my urologist ran a test and told me you have a one percent of still being here at 10 years and so I went for the therapy and my PSA keeps dropping and I know I have beat it.

I have a 3+4 and a 4+3 what does it mean?