Mothership Theory

What does it say? That you have ro remove the prostate to remove one potential source of future recurrences? I.e., that radiation has a persistent long-term risk?

Dr Walsh's book just reports on it. The radiotherapy arm of the broad phase III STAMPEDE trial found (among many other things) that for oligometastatic prostate cancer, radiating the prostate itself *in addition to other treatments* extends survival without serious impact on quality of life. This was already become standard practice at my cancer centre in 2021 when I was diagnosed.

(Unfortunately, they did not find any benefit for polymetastatic prostate cancer.)
https://ascopost.com/news/august-2022/long-term-benefit-of-radiotherapy-confirmed-in-advanced-prostate-cancer-stampede-trial-follow-up/

I think it says that surgery or radiation on the prostate is valuable even if there are metastatic spots because the escaped cells are out circulating and still communicating with the original tumor (the mothership). And this communication strengthens and invigorates the circulating cells.