Mirvetuximab for ovarian cancer: Anyone used this drug yet?

Posted by califcheryl @califcheryl, Nov 9, 2024

has anyone done treatment for ovarian cancer with the IV infusion drug Mirvituxim. I'm starting next Wed. I've done 6 chemo treatment with platinum based carbonplaxin and had full hysterectomy surgery, but there was still many cancer cells left in my abdominal wall. The cancer became resistive to carboplaxin so they are going to try this new drug.

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Colleen Young, Connect Director | @colleenyoung | Nov 18, 2024

@califcheryl, I'm glad that mirvetuximab (Elahere) offers an option for you. It was only recently approved (March 2024) for people whose ovarian cancers are platinum-resistant.

How was the first treatment session? How many will you have?

clairelt | @clairelt | Nov 19, 2024

I am eligible to use this in the future but am not currently platinum resistant.
I am interested to hear about your experience.

califcheryl | @califcheryl | Nov 21, 2024

In reply to @clairelt "I am eligible to use this in the future but am not currently platinum resistant. I..." + (show)

Just had first injection. Was a long one about 3 hrs. Eye lubricant definitely need as my eyes did feel very dry during night, but lubricant drops immediately helped. So far no other side effects.

jm | @jodimj | 6 days ago

Are you still on it and what are your results and experiences with it so far?

califcheryl | @califcheryl | 5 days ago

I have had 5 infusions so far. First one, I got alot of nausea. But all the rest, no nausea. Eyes get a bit dry, but the eye lubricant helps with that. The last infusion, my vision got a little blurry. They prescribed a special sterile eye drop and AREDs vitamin to help with that. Key thing is my CA125 went from 1025 to 116 after just 3 infusions. Waiting for the results coming this Wed for results as of 4th infusion. I have PET scan scheduled for next week for a more visual confirmation of the progress

califcheryl | @califcheryl | 3 days ago

In reply to @califcheryl "I have had 5 infusions so far. First one, I got alot of nausea. But all..." + (show)

Got my CA125 results today (after 4th infusion). I am at 58. (I started at 1025 in Nov. before the first Mirvituxim infusion). So it's working well

jm | @jodimj | 3 days ago

In reply to @califcheryl "I have had 5 infusions so far. First one, I got alot of nausea. But all..." + (show)

Are you taking anything else like Avastin with it?

califcheryl | @califcheryl | 3 days ago

In reply to @jodimj "Are you taking anything else like Avastin with it?" + (show)

I dont take Avastin. I'm on Atorvastatin and Plavix to help prevent blood clots as a result of a few TIA mini strokes I had in Nov 2023. Also take Gabapenthin to help with my hand and feet neuropathy pain.

Helen, Volunteer Mentor | @naturegirl5 | 3 days ago

In reply to @califcheryl "Got my CA125 results today (after 4th infusion). I am at 58. (I started at 1025..." + (show)

@califcheryl This is good news and very encouraging!

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