Lupron Treatment Duration: How long were you on it?

Posted by frankstags @frankstags, Jul 7, 2020

I have been diagnosed with Grade 3 prostate cancer with a 4 + 3 Gleason score of 7. This after having 2 PSA scores last year between 4 and 7. The cancer has not spread to the bones. I have received two Lupron injections 3 months apart and will complete 28 radiation treatments in the next couple of days. No surgery. I have tolerated the Lupron shots well with few but manageable side effects. I have an appointment to receive a third Lupron shot next month. My first PSA test after completing radiation won't be scheduled for 3 months. From researching Lupron, it appears that this is used for advanced stages of prostate cancer. From what I was led to believe, I was not advanced. My question: How long and how many Lupron shots might I need to go through? I will have this discussion with my urologist hopefully before proceeding with the next shot. Thanks for any information provided by the group.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Is anyone in the group on ABI/Predisone? My husband was diagnosed wht Castrate-resistant Metastic Prostate Cancer one year ago in June and the cancer had come back in his pelvic area. He than had 36 appointments of radiation, followed by Eligard-Lupolide shots every 6 months along with 4 tablets of the ABI-Predisone. Very tired and not much of an appetite or drinking fluids, and now has been off of it for two weeks. I was told to bring him to emergency room for fluids, and after much testing they found out he had blood clots in both lungs. He is now home after 10 days in hospital and does not want to go back on ABI/Predisone.

REPLY
Profile picture for kujhawk1978 @kujhawk1978

Not sure if you are saying the radiation and ADT as your primary treatment vice BCR..

This may help if so ...https://www.prostatecancer.news/2022/01/optimal-duration-of-adjuvant-adt.html

Kevin

Jump to this post

An excellent way to Reply, Kevin: not simply individual opinion, but published material.

Sure hope you're around for questions I might post!

REPLY

I was Gleason 9 and I did 3 years of Lupron (after 6 weeks of radiation). It wasn't fun, but it wasn't horrible, either. Maybe I was lucky.

REPLY
Profile picture for kujhawk1978 @kujhawk1978

Not sure if you are saying the radiation and ADT as your primary treatment vice BCR..

This may help if so ...https://www.prostatecancer.news/2022/01/optimal-duration-of-adjuvant-adt.html

Kevin

Jump to this post

Thanks much for the note and data. Had extensive radiation and am now on Hormone therapy. Pet scan showed no cancer beyong the Prostate and the Radiologist still traeted the lymph nodes with radiation just in case. I want to stop at 18 months with Hormone but getting some pressure from urologists to continue furthur.

REPLY
Profile picture for mtv @mtv

I had Gleson 9 confined to prostate. Had 45 bouts of radiation and now on Hormone therapy for 6 months plus. I am doing fine but want to stop Hormone usgae when it is medically approprate. What is now the required amount of months to be on Hormone therapy.

Jump to this post

Not sure if you are saying the radiation and ADT as your primary treatment vice BCR..

This may help if so ...https://www.prostatecancer.news/2022/01/optimal-duration-of-adjuvant-adt.html

Kevin

REPLY

I had Gleson 9 confined to prostate. Had 45 bouts of radiation and now on Hormone therapy for 6 months plus. I am doing fine but want to stop Hormone usgae when it is medically approprate. What is now the required amount of months to be on Hormone therapy.

REPLY

I'm on orgovyx as opposed to Lupron, but, maintenance seems very doable, gains are tough. It took me quite a bit of time to get back to where I was before I had the operation and then started Lupron. Getting past those numbers was a hell of an effort.
Don't get me wrong, still doing 4 weight sessions a week and running after. Feel great after the workouts, but, don't feel I'm going to gain much in the max weight dept.. (still on the meds though, perhaps it will improve after I stop taking them.). 138 days, but who's counting? ME!

Hang in there!!

REPLY

I was on lupron 13 months, off it now for 12 months, gained much weight. I had a client who was on it for 10 years. I am gleason 9, advanced, CR. If I need to go back on it I will inquire if Lupron + Erleada + chemo would be recommended for me. staying alive is not fun nor easy but it is a battle worth fighting. I don’t know if shooting for a cure is in the cards for me

REPLY
Profile picture for drj @drj

Thanks for your comments. The initial diagnosis was by a urologist of course, a surgeon, but you are right: when I chose radiation, I was of course in the hands of a radiation oncologist. The post-radiation follow up includes the radiation oncologist, but now it's primarily a medical oncologist for tracking Lupron treatment which is done quarterly. For the latter, questions in writing and in person re. Lupron length versus effectiveness have always been deflected or elided. My current issue is whether there is significant value to returning to the gym, particularly absent testosterone. How are you dealing these cards?

Jump to this post

Hi

I'm new here, but the gym question really interests me. I was on Lupron for 3 years (Gleason 9, PSA 28, radiation + ADT, I'm 63 years old). Now my PSA is creeping up again, so I may have to go back on Lupron. During Lupron I did light exercise, but no weighlifting. Before cancer I could do 30 pushups. After 3 years of Lupron I could do 6. I also gained 30 pounds around the middle.
But, my last Lupron was in April of '23 and I'm lifting weights like mad 3x a week and I can now do 22 pushups. I plan to try to lift weights 3x per week for the rest of my life (it helps me mentally, too).

REPLY
Profile picture for narus @narus

Lupron literally sucks the life out of you. You cannot reduce your testosterone to zero without affecting your quality of life.
I have also had bladder issues after proton radiation. I would be washing the dishes when the urge comes and if I am not in the bathroom in 15 seconds I am going to wet myself.
I have used an external catheter for long drives and it worked well.

Jump to this post

Amazon and it is a lot cheaper than endlessly buying Depends.

REPLY
Please sign in or register to post a reply.