Lupron Treatment Duration: How long were you on it?

Posted by frankstags @frankstags, Jul 7, 2020

I have been diagnosed with Grade 3 prostate cancer with a 4 + 3 Gleason score of 7. This after having 2 PSA scores last year between 4 and 7. The cancer has not spread to the bones. I have received two Lupron injections 3 months apart and will complete 28 radiation treatments in the next couple of days. No surgery. I have tolerated the Lupron shots well with few but manageable side effects. I have an appointment to receive a third Lupron shot next month. My first PSA test after completing radiation won't be scheduled for 3 months. From researching Lupron, it appears that this is used for advanced stages of prostate cancer. From what I was led to believe, I was not advanced. My question: How long and how many Lupron shots might I need to go through? I will have this discussion with my urologist hopefully before proceeding with the next shot. Thanks for any information provided by the group.

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Profile picture for vinny59 @vinny59

Had two injections of Lupron on the three month shot, starting radiation in two weeks, I have flu like symptoms horrible cough, insomnia, and hot flashing to name a few lol. They are telling me three years of this argh I have Gleason score of 9 high risk but no metastasis to bones. I think that you should get off it if your PSA numbers come down to normal

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I have Gleason of 9 or higher too, will come off Trelstar/ Lupron in 24 months to see if PSA changes. Have lots of fatigue/ mild hot flashes- age 75-FYI

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Had two injections of Lupron on the three month shot, starting radiation in two weeks, I have flu like symptoms horrible cough, insomnia, and hot flashing to name a few lol. They are telling me three years of this argh I have Gleason score of 9 high risk but no metastasis to bones. I think that you should get off it if your PSA numbers come down to normal

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In May 2012, I had my first injection of Lupron with the biggest needle I have ever seen in my life. Today at my age of 70 I am still having Lupron injections. My PSA was 4.87 when diagnosed and my scores were all above 10. Cancer has never been in remission and only moderately controlled. I keep seeking

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I am not sure if I mentioned he was so dehydrated that the VA sent it to the hospital for fluids. He ended up having blood clots in both of his lungs. He had been off of Abi/predisone For a few days, but now it’s been three weeks. After four days in the hospital knee swelled up And they took two vials of fluid off of it three days later he had surgery to clean it out. I’m just wondering if it’s antibiotics that is making him so fatigued.

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Profile picture for Colleen Young, Connect Director @colleenyoung

Welcome, @pennyoverhill. Several members have talked about treatment with Abiraterone with prednisone like @mikesuess @ncoic @ringmastr1 @lag @lmacfive @joecontheroad.

How is your husband doing? Did he resume treatment?

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No his quality of life isn’t great when on it. Sees his oncologist next week. He is so weak and exhausted

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Gleason 4+3 worse than 3+4. ADT helps shrink prostate before radiation.

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I've been fortunate enough to not be severely affected by the Abiraterone, Prednisone and lupron. It's incredibly important to stay well hydrated in general to help mitigate other side effects.

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Profile picture for pennyoverhill @pennyoverhill

Is anyone in the group on ABI/Predisone? My husband was diagnosed wht Castrate-resistant Metastic Prostate Cancer one year ago in June and the cancer had come back in his pelvic area. He than had 36 appointments of radiation, followed by Eligard-Lupolide shots every 6 months along with 4 tablets of the ABI-Predisone. Very tired and not much of an appetite or drinking fluids, and now has been off of it for two weeks. I was told to bring him to emergency room for fluids, and after much testing they found out he had blood clots in both lungs. He is now home after 10 days in hospital and does not want to go back on ABI/Predisone.

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Welcome, @pennyoverhill. Several members have talked about treatment with Abiraterone with prednisone like @mikesuess @ncoic @ringmastr1 @lag @lmacfive @joecontheroad.

How is your husband doing? Did he resume treatment?

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Is anyone in the group on ABI/Predisone? My husband was diagnosed wht Castrate-resistant Metastic Prostate Cancer one year ago in June and the cancer had come back in his pelvic area. He than had 36 appointments of radiation, followed by Eligard-Lupolide shots every 6 months along with 4 tablets of the ABI-Predisone. Very tired and not much of an appetite or drinking fluids, and now has been off of it for two weeks. I was told to bring him to emergency room for fluids, and after much testing they found out he had blood clots in both lungs. He is now home after 10 days in hospital and does not want to go back on ABI/Predisone.

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Profile picture for kujhawk1978 @kujhawk1978

Not sure if you are saying the radiation and ADT as your primary treatment vice BCR..

This may help if so ...https://www.prostatecancer.news/2022/01/optimal-duration-of-adjuvant-adt.html

Kevin

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An excellent way to Reply, Kevin: not simply individual opinion, but published material.

Sure hope you're around for questions I might post!

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