Lupron Treatment Duration: How long were you on it?

Posted by frankstags @frankstags, Jul 7, 2020

I have been diagnosed with Grade 3 prostate cancer with a 4 + 3 Gleason score of 7. This after having 2 PSA scores last year between 4 and 7. The cancer has not spread to the bones. I have received two Lupron injections 3 months apart and will complete 28 radiation treatments in the next couple of days. No surgery. I have tolerated the Lupron shots well with few but manageable side effects. I have an appointment to receive a third Lupron shot next month. My first PSA test after completing radiation won't be scheduled for 3 months. From researching Lupron, it appears that this is used for advanced stages of prostate cancer. From what I was led to believe, I was not advanced. My question: How long and how many Lupron shots might I need to go through? I will have this discussion with my urologist hopefully before proceeding with the next shot. Thanks for any information provided by the group.

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Profile picture for melcanada @melcanada

According to seers.gov.ca we have 30% chance of 5 years

Your thoughts

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I was diagnosed with metastatic prostate cancer 11 years ago, had a total prostatectomy and was put on intermittent Lupron therapy. After about five years, they had to put me on standard every three month Lupron therapy. Two years ago as my PSA was becoming higher and higher they added an anti-androgen agent, abiraterone. So far that has been keeping my PSA under control. However, there are signs that we may have to look at additional therapy going forward. FYI, I am 83 years old and in reasonably good physical shape aside from the cancer. I ride my bicycle 6-8 miles and work in my yard every day
Thank you, Lord!

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Profile picture for yell0wsub @yell0wsub

I had Lupron, on and off, depending on testosterone and PSA, from 2006 to 2021. Now it’s every 6 months.

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According to seers.gov.ca we have 30% chance of 5 years

Your thoughts

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Profile picture for scullrower @scullrower

I’ve been on Lupron since 2016. My understanding is that any treatment, including Lupron, is guided by the PSA and the findings of good scans.

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I had Lupron, on and off, depending on testosterone and PSA, from 2006 to 2021. Now it’s every 6 months.

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Profile picture for melcanada @melcanada

Testosterone is the fertilizer for prostate cancer You have 10 fingers and a tongue so live and forget about erections

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I could not have said it better!

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Profile picture for ken1946 @ken1946

I was on Lupron for two-full years. Also had RP and radiation treatments. I have been off of it for over a year. I am waiting for the erections to come back. I was assured that they would once I stopped the Lupron injections.

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Testosterone is the fertilizer for prostate cancer You have 10 fingers and a tongue so live and forget about erections

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Profile picture for thomaswmartin @thomaswmartin

Thank you. Interesting. I had Gleason 9 psa 22. Staged 3C. Prostate too large to remove. Had radiation and then chemo (taxotere). Been on lupron for approx 1 yr. Completed radiation and then chemo 7 mos ago. They’re telling me I need to stay on lupron for life. I don’t like the effects…libido obvious but also tiredness, trouble focusing and some leg and balance issues. I still run my business and blessed with energy at 78 to fight this. They said it metastasized but not in tissue, organ, bone or lymph nodes per scans. This is also my 2nd cancer bout. Throat cancer 13 yrs ago stage 4.

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I’ve been on Lupron since 2016. My understanding is that any treatment, including Lupron, is guided by the PSA and the findings of good scans.

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I was on Lupron for two-full years. Also had RP and radiation treatments. I have been off of it for over a year. I am waiting for the erections to come back. I was assured that they would once I stopped the Lupron injections.

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Profile picture for thomaswmartin @thomaswmartin

Thank you. Interesting. I had Gleason 9 psa 22. Staged 3C. Prostate too large to remove. Had radiation and then chemo (taxotere). Been on lupron for approx 1 yr. Completed radiation and then chemo 7 mos ago. They’re telling me I need to stay on lupron for life. I don’t like the effects…libido obvious but also tiredness, trouble focusing and some leg and balance issues. I still run my business and blessed with energy at 78 to fight this. They said it metastasized but not in tissue, organ, bone or lymph nodes per scans. This is also my 2nd cancer bout. Throat cancer 13 yrs ago stage 4.

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After 5 years and metastases to L2 lumbar I am back on Zolodex PSA dropped from 25 to 1.2 with radiation of 1 inch off L2 and injections every 3 mos of Zolodex

Try Zolodex no side affects for me

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Profile picture for thomaswmartin @thomaswmartin

Thank you. Interesting. I had Gleason 9 psa 22. Staged 3C. Prostate too large to remove. Had radiation and then chemo (taxotere). Been on lupron for approx 1 yr. Completed radiation and then chemo 7 mos ago. They’re telling me I need to stay on lupron for life. I don’t like the effects…libido obvious but also tiredness, trouble focusing and some leg and balance issues. I still run my business and blessed with energy at 78 to fight this. They said it metastasized but not in tissue, organ, bone or lymph nodes per scans. This is also my 2nd cancer bout. Throat cancer 13 yrs ago stage 4.

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Hi Thomas, those are tough symptoms to manage, especially the fatigue and focus isses while still running a business. Do you work at a home office where you can pace yourself and take breaks as needed?

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Profile picture for visaliajoe @visaliajoe

I must be unusual. I had a Gleason of 9 with not spreading. I had a Lupron shot prior to Barchy treatment. I refuse beam radiation after my first PSA was .o4. I also refused another Lupron shot. My PSA's have all been less then 1. When I refuse the beam radiation my urologist said wise move but was not as happy when I refused the second Lupron shot. But said we will wait and see. I was rushed to have the initial procedure because of my Gleason but after that no pressure. Please, remember you are in control.

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Thank you. Interesting. I had Gleason 9 psa 22. Staged 3C. Prostate too large to remove. Had radiation and then chemo (taxotere). Been on lupron for approx 1 yr. Completed radiation and then chemo 7 mos ago. They’re telling me I need to stay on lupron for life. I don’t like the effects…libido obvious but also tiredness, trouble focusing and some leg and balance issues. I still run my business and blessed with energy at 78 to fight this. They said it metastasized but not in tissue, organ, bone or lymph nodes per scans. This is also my 2nd cancer bout. Throat cancer 13 yrs ago stage 4.

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