Lupron Treatment Duration: How long were you on it?
I have been diagnosed with Grade 3 prostate cancer with a 4 + 3 Gleason score of 7. This after having 2 PSA scores last year between 4 and 7. The cancer has not spread to the bones. I have received two Lupron injections 3 months apart and will complete 28 radiation treatments in the next couple of days. No surgery. I have tolerated the Lupron shots well with few but manageable side effects. I have an appointment to receive a third Lupron shot next month. My first PSA test after completing radiation won't be scheduled for 3 months. From researching Lupron, it appears that this is used for advanced stages of prostate cancer. From what I was led to believe, I was not advanced. My question: How long and how many Lupron shots might I need to go through? I will have this discussion with my urologist hopefully before proceeding with the next shot. Thanks for any information provided by the group.
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Hello,
I was diagnosed at age 66 with G8 4+4 PC, the treatment that I chose was radiation and that was 45 treatments over 9 weeks and then 12 months of Lupron. Ice been off Lupron for 1 year now but I have no Libido, no stirring, no desire to even try, if I try to master bate it's like beating a dead horse, I have a penile implant but there just aren't any feelings, my breast's became moobs and I really would enjoy intimacy with my wife again but there just isn't any fuel in the tank. I have no idea if I'll ever feel intimacy again and now I'm only 68 years old, to young to just give up.
Thanks for reading, any comments are welcomed
I too was 4+3 G7. 66 year old, PSA was 10 after a failed Hi-Fu. I was informed by my radiologist that based on my numbers, ADT was recommended to compliment the radiation effectiveness. It seems there is a higher success rate when combined. Not wanting to take any more chances, I went with the prescribed 4 mth ADT program and 28 Rads. Testosterone went to 2.5. After 9 mths, PSA still undetectable 0.02, However, most recent PSA showed slight uptick to 0.08, (T level reached 300), hopefully nothing to worry about.....Best to all
@rkj2019, you may be interested in these related discussions:
- Gynecomastia (male breast enlargement) bc of ADT-prevention/experience https://connect.mayoclinic.org/discussion/gynecomastia-male-breast-enlargement-due-to-adt-can-it-be-prevented-1/
- Gynecomastia while taking hormone therapy for prostate cancer https://connect.mayoclinic.org/discussion/gynecomastia-while-taking-hormone-therapy-for-prostate-cancer/
- Can we talk about boobs please? Man Boobs. ADT induced gynecomastia. https://connect.mayoclinic.org/discussion/can-we-talk-about-boobs-please-man-boobs-adt-induced-gynecomastia/
You can use keywords in the group search to find other related discussions, like https://connect.mayoclinic.org/group/prostate-cancer/?search=Leg+weakness#discussion-listview
I was on luprone and Erleada for a year and it was tolerable. Some brain fog, flashes, sleep disorder , loss of sex drive but it was medicine that has helped to keep me undetectable for 3 years. I am G 9, CR, locally advanced.
What are /were your side-effects from Lupron and also Nubeqa? Do you have libido after all hormonal therapy? Leg weakness, joint pain, brain fog, gynecomastia?
I was on Lupron several years. The last time my cancer recurred I went to UCLA for a PSMA PET scan. Four metastases were found. I underwent SBRT for them, took Nubeqa for 24 months, then stopped all treatment. My PSA has been < 0.008 since.
Late to the conversation. Just wondering why your not seeing an oncologist at a cancer center? I was diagnosed with agressive metastatic stage 4b pc. PSA 40. Gleason scores all 4+5 or 5+4, Pirads 5. Spread to pelvic bones and lymph nodes. 6 docataxel chemo treatments, 6 radiation treatments, 2 years Lupron and Nubeqa and PSA is holding at .02. PET scan shows no cancer. Even bone cancer is gone. I went to MN Oncology. Just can't say enough about the great treatment I got there.
I was diagnosed at 71 psa was 7.3 I had minor EPE and ended up having radiation for 28 days and was on Lupron for 2 yrs with injection every 3 months .
I also was treated with Casadex for 2 years.
I am 74 now and have been off of Lupron and Casadex for 16months.
My psa is undetectable and my T is starting to come back!
@zr2, that's a tough decision when specialists offer differing opinions on the length of ADT. Did you stop after 9 months or will you continue? Did you bring the urologist's evaluation to the oncologist to discuss?
Age 74, Gleason 7 (4+3) diagnosed 2/15/22. Lupron 3/27/22, IMRT 39 ZAPS,
9/1/22 Zytiga + Prednisone.
As of 8/15/24 (Date of freedom from drugs and treatment)
24 mos of zytiga
30 mos of lupron
39 zaps of IMRT
BOY AM I TIRED! Now age 77
Good luck to all you guys.