Lupron: Anyone have muscle weakness and severe leg pain?

Thanks. You also. I did have pain in knees and calf at 9 months. Would keep me up half the night. It cleared in about 2months. I took marijuana gummies occasionally to help get to sleep. (Legal in my state.)

Hopefully the hamstring pain will take a similar course an reduce over time.

Thank you. My story is very similar to yours..Stage4 (to start), Lupron, chemo (Docetaxel), and radiation. Twelve months later clear but doc wants me to continue Lupron 2-3 more years if possible. Facing same decision on lifestyle. I have read that monthly injections have less side effects. Am getting switched to those starting with my next dose of Lupron.

Thank you. Are you off the ADT now? How long after ending the ADT did it take you to return to normal?

I'm on Eligard. I have Stage 4, advanced, agressive, Gleason 9 PC. After nine months, I can barely get up from chair because of stiffness and pain in my legs, have some pretty good hot flashes about once an hour, have lost some muscle, lots of fatigue. I also have heart failure so the oncologist is considering stopping the Eligard as it can cause heart attacks. Leuprolide seems to me to be a good drug/bad drug and everyone has to weigh their own risk/reward status with it. I'm really wondering if I should stop the drug (regain some lifestyle normalcy) and hope the PSA stays low or continue another nine months with the side effects that are changing my way of life. Big decision ...

Definitely try to fight the rocking chair and find an activity to keep in motion. I'm 9 months into adt (eligard + zytiga + prednisone) and my biggest gripe with muscle pain is the increased sensitivity to any inflammation and that it takes weeks if not months for healing. The mental brain fog is also a challenge. Keep the faith, you can find the way.

I was on Lupron three month injections for about five years. It was not easy and lost massive amounts of muscle mass during that time. I was a physical education teacher, and college wrestler and I’ve tried WT room many times with limited results. Best thing I have found for myself is working in my garden. Something I enjoy doing, and it has helped a little bit. It’s a tough road to haul especially I think if you were in very good health physically before the cancer. Everyone is different I do think that the ADH with Zytiga and prednisone has kept me alive so far. Good Luck and try and stay on treatment if you can.