Lupron: Anyone have muscle weakness and severe leg pain?

Lupron severely adversely effects your muscles. I have difficulty getting out of my chair and unstable in my walking. Gleason 9, CR, aggressive, locally advanced. I am told that it helps to keep me alive so I willingly accept the side effects. I was taken off all meds 10 months ago but I still feel side effects from Lupron and Erleada

Ditto for me. Lupron isn't easy

I identify with your leg pain. Gleason 9. Metastatic. I’ve done chemo and radiation, now on Lupron and Nubeqa. So weak I can hardly climb steps. Physical therapy helps. Several short walks or exercise bike rides per day seems to help.

Hand pain. I was on Lupron and Erleada for 13 months and I have been off all meds now for 10 months. About a month ago I got pain in my right hand and fingers and I cannot now make a fist and the palm and back of that hand and fingers ache and burn and hurt. The pain is now starting in my left hand. Has anyone else had this sort of problem and if so can you give me a recommendation. Tylinol 8 hr and arthritis cream help, but I am looking for other treatment. Thanks

Been on Lupron since April 2023 and had leg pains. Upon speaking to a pharmacist who had worked in oncology he recommended taking an antihistamine like 24 hour Allegra or Claritin. Since taking Allegra I've had very few leg cramps. A few 1 to 2 a week much milder ones occur in the first ten days after the injection. He told me they studied leg cramps and found those patients taking 24 hour antihistamines rarely had leg cramps. Might want to give it a try. Good luck!

TRY theraworx from Walgeens generic Rub it on muscles

I'm glad you brought up this topic. I was going to ask a few questions. Age here, 69, had radiation back in
March-early May. Also Eligard hormone shot. What I've noticed is tolerable, but unpleasant.
Eligard side effects, aching muscles, joints, hips, shoulders....reduced interest in things I enjoy,
fatigue...some burning while urinating, and of course, hot flashes. Anyone else have these
similar side effects? Thank you. Oh....and I almost forgot, tingling hands, arms, sore knuckles.

Thanks for the recommendations. I read the book “Starving Cancer “ and decided to combat the cancer on as many fronts as possible. Found a great Natural Pathic doctor (ND). Changed my diet. Switched to organic non processed foods. Got high dose Vitamin C infusions (100g) which in that concentration and iv creates an oxidative environment which cancer doesn’t like. Many supplements as directed by the ND. Did all this is addition to finding a great Doc at Mayo that also treated my cancer aggressively.
Keep up the good fight.

I will pray for your fast recovery bud. I only have to deal with peeing every 3 minutes now and taking a anti pee all the time pill but must take time to work.

Thank you for your post. So encouraging to hear success stories and faith. Made my day.

I should also note that my severe leg pain got got much worse before we finally found the cause. CT showed no problems but MRI showed that three of my vertebrae had almost completely closed off internally thereby pinching the nerves . Had back surgery a week ago and the leg pain was gone in the recovery room. Many thanks for the prayers and responses.
Muscle weakness still there but I can at least now implement the recommended strengthening exercises.