Letrozole: When will I start feeling/seeing side effects?

I started Letrozole just over a year ago. First started taking it in the morning. Few days after around 4pm ish I
passed out at the driving wheel. Completely out! Smashing into empty cars, driving on wrong side of the street. Air bags all went off. Thank god I never hit a human or a dog. Lot of dog walkers in my town. Car was a write off, had only had it a few months. Only thing I remember was a medic putting his head in my window to ask if I was ok. Legs were bruised and cut from air bags is all. My main concern was that no one else had been hurt. The cars I hit were empty. Then I ran into someone’s porch which stopped my car. What a nightmare! Then I read the side effects sheet it said be careful about driving etc. Now I take it at bedtime. Had no problems since. Otherwise that was as it as far as side expects. Thank goodness.

I started Letrozole just over a year ago. First started taking it in the morning. Few days after around 4pm ish I
passed out at the driving wheel. Completely out! Smashing into empty cars, driving on wrong side of the street. Air bags all went off. Thank god I never hit a human or a dog. Lot of dog walkers in my town. Car was a write off, had only had it a few months. Only thing I remember was a medic putting his head in my window to ask if I was ok. Legs were bruised and cut from air bags is all. My main concern was that no one else had been hurt. The cars I hit were empty. Then I ran into someone’s porch which stopped my car. What a nightmare! Then I read the side effects sheet it said be careful about driving etc. Now I take it at bedtime. Had no problems since. Otherwise that was as it as far as side expects. Thank goodness.

When do most people start side effects from Letrozole? I have a lot of angst about taking it. I started two weeks ago and feel nothing other than fatigue, which in my case could be coming from a couple things. I take it at noon with other meds.

If you are able, can you let go of your concern about possibilities and just see how it goes? Easier said than done, I know. But I believe about half of women on letrozole can tolerate it--although a significant portion do suffer. I've been on for a year and a half and no problems. Hope things continue easily for you.

When do most people start side effects from Letrozole? I have a lot of angst about taking it. I started two weeks ago and feel nothing other than fatigue, which in my case could be coming from a couple things. I take it at noon with other meds.

Hey, edwendt! Kudos to you for doing your best at protecting yourself, even through non-positive side effects! 1st, each person's body will likely react differently to any drug, so remember that your experience may not be exactly like mine. I took Letrazole for 5 years after lumpectomy and radiation. It made me nauseous, also. I finally found 2 things to be true for me: 1st, if I took it before bed, on a full stomach, the nausea was much dimmenished. 2nd, after a period of time (couple of weeks, maybe?) the nausea seemed to lessen and go away. I encourage you to continue to do the best you can, and to seek help if it becomes too much. Hugs and best wishes to you on your journey!! God bless you!!

i've been on it now a couple of months since my mastectomy and I feel nauseous all the time. i've tried taking it with lots of water, food, not with other meds i take etc-but the nausea doesn't change.
anyone else feel nauseous?