Anyone on chemo every week being treated with carbo and abraxane?

Posted by lillard @lillard, Mar 15 4:02pm

I was diagnosed with high grade serous carcinoma of the ovary and Fallopian tube. Christmas and had surgery to remove that. I couldn't go through debunking surgery because of poor health conditions. I'm believe to be stage 1. They decided to start chemo right away the carbo and pacitaxol. I'm on my second treatment. I'm receiving it every week. Is anybody else also on this treatment plan and if so how is it working for you and side effects?

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I was diagnosed with stage 3B, I had 6 rounds of carbo, paclitaxel, avastin every 3 weeks, CA125 was in normal range after full hysterectomy and went down to 7, many side effects, "bone" pain, mainly in legs, hair loss, peripheral neuropathy (lasting), high blood pressure, constipation, loss of taste and appetite, constantly feeling cold, low red blood cells, low platelets and other
changes in blood due to chemo- not everyone will experience these side effects-

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@lillard, I hope you saw the reply from @charlotte12 who has also had treatment with carbo and paclitaxel, as well as avastin. I'm also tagging @kristinfloyd1 @msfarn @saro2012 @rdubins who may have additional experiences to share.

@lillard, how are you doing?

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I was on the same from July 2023 to Feb 2024. I would be happy to talk anytime if you would like to message me.

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@msfarn

I was on the same from July 2023 to Feb 2024. I would be happy to talk anytime if you would like to message me.

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@lillard If you'd like to talk privately with @msfarn you can private message her. You can do that by clicking on her screen name @msfarn and that will take you to her profile. On the left side of the computer screen of her profile you will see a big blue box with an envelope icon and the words "Send Private Message".

How are you feeling today?

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I tolerated it pretty well. The third day I usually felt crummy and would take the nausea meds. Are you icing your hands and feet? The nurses did it with baggies the first chemo then I bought some mitts and booties on Amazon. I had no neuropathy. My neutrophils went down and my liver enzymes were high at times. I lived a pretty normal life through it. I did stay away from crowds even the grocery store. I’m now a year and 8 months since diagnosis with no reoccurrence.

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I had six rounds of carboplatin/paclitaxil for OC Stage 3b between April and August 2024. Days 3 and 4 after a treatment were always the hardest...joint pain (mostly hips, knees, feet), neuopathy in hands feet and lips (until they decreased the dose on treatment #4), and extreme fatigue/low stamina. Nausea wasn't too bad, surprisingly. I returned to work part-time on day 5 after a treatment and then worked a normal schedule for weeks 2 and 3. I didn't feel great during those two weeks but I could manage. My WBC's and RBC's got pretty low and I was very short of breath but I didn't need a transfusion. Now, 7 months since treatment ended, my blood counts are back to normal, and other than mild neuropathy in my feet I feel pretty much back to baseline. I consider myself extremely fortunate. One thing I hadn't predicted was how much the treatment staff became a support network....in a weird way I enjoyed aspects of the treatments because I got to spend time with people who I liked so much.

I hope you have the best experience possible with a situation you never wanted or asked for. It's pretty amazing how much we can deal with when we have no choice. Big hugs to you.

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@lillard You've received some helpful replies from others who had the same chemotherapy regimen as you. How are you doing?

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I too was treated with nab-paclitaxol (abraxane) and carboplatin, and my side effects were the same as everyone else's described here. My peripheral neuropathy never abated--fingers and toes, stiff ankles also. Hair grew back within 6 months after treatment, and after a year, it looks the same as it did before treatment. So, fear not.
I have to say that less than four months after treatment, my cancer antigen numbers started to rise again, esp. CA 19-3. Anew tumor appeared in vaginal vault and pelvic lymph nodes. Thus, I conclude that my cancer is platinum resistant. I have high grade serous cell endometrial cancer type 2, stage III3C. I am HER positive +2.
Currently in a clinical study testing the effects of Enhertu on HER2 endometrial cancer. Have received 2 cycles of the drug, and am tolerating it fairly well; the side FX are way milder than those of pac/carb.
Hope this helps somewhat and gives you another option of treatment if need be.

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