Immunotherapy with Clear Cell Carcinoma- Endometrial

@ccwill There are new approaches coming out from clinical trials that benefit us. It sounds like you are following the recommendations of your oncologist and it’s worked for you. Here is what I’m doing to help with the anxiety over cancer (diagnosed with endometrial cancer in 2019, recurrence in 2021). I remind myself that some cancers can be treated as a sort of chronic disease that needs careful monitoring. I keep to the quarterly schedule of my cancer surveillance appointments and follow the recommendations of the doctors and nurses that I see.

As @paula21 wrote you have to take charge of what you can control.

I just completed six cycles of chemo with Keytruda. I believe the chemo would not have worked had it not been for Keytruda. My oncologist will continue me on 400mg of Keytruda every six weeks, for another year, barring any adverse effects which could occur, death or cancer progression.

Absolutely. You can't sit back and hope for someone to fix you. You have to be in charge of the things you can control.

@paula21 Your mind and body are going through so much right now that’s no wonder you feel fatigued. I’ve also consulted with a nutritionist whose speciality is cancer and it’s been so very helpful. Doesn’t it feel great to know that you can do something yourself (nutrition) that will contribute to your health?

I feel fine. I have a little fatigue but this could also be the new diet.

@paula21 This sounds promising. How are you feeling today?

I restarted Keytruda/Lenvima last Thursday, the 14th. The next day, I had an outbreak of red blotches on my upper arms and lower legs. I took Benadryl and applied a steroid cream I had been given by my dermatologist. These two are working to keep my skin reactions under control. I'm so relieved. I'm also working with a nutritionist on a healthy diet.

@paula21, did you start Keytruda/Lenvima? How are you doing?

Hi, I too am battling clear cell endometrial cancer. I'm 68 living in Henderson, NV. Had radical hysterectomy in March 22, followed by Taxol chemo. The cancer spread during chemo. I then started Keytruda and Lenvima. Pet scan after 5 treatments finally showed really good results. Unfortunately, I began having skin blisters and so Keytruda was stopped until it cleared up. After 2 more treatments, my Pet Scan showed I metastasized all over the place: lung and bone. I've now consulted with a new oncologist for a second opinion. He wants to put me back on Keytruda and Lenvima this week. He says that my treatment is not curative. I will restart the Keytruda/Lenvima this Thursday. I believe that Keytruda is only given after traditional chemo has failed.

You may find this article interesting https://ascopost.com/news/march-2021/pembrolizumablenvatinib-may-improve-survival-in-advanced-endometrial-cancer/