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If or how should the new diabetic drug be incorporated for Diabetes II

Posted by sad43 @sad43, 3 days ago

I have type II diabetes with some chronic kidney disease. The drugs prescribed when I was first diagnosed 25 years ago have not changed since, except for changes to the amount of Metformin. What, if any, changes should be made to my current regimen, especially based on the wide variety of new drugs that have been developed in the past 20 years?
My current regimen is: Metformin ER 2x500mg , glipizide 10mg am, 5mg pm, lisinopril 2.5mg, Atorvastatin 10mg.

Thanks SAD

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grrranny | @grrranny | 3 days ago

I was diagnosed 28 years ago. You might ask your doc about just increasing the metformin and glipizide.
After using only diet and exercise the first 23 years, I was taking twice those amounts (up to max dosage) in addition to daily exercise a few years ago before starting on insulin 3 years ago.

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sad43 | @sad43 | 3 days ago
In reply to @grrranny "I was diagnosed 28 years ago. You might ask your doc about just increasing the metformin..." + (show)
Profile picture for grrranny @grrranny

I was diagnosed 28 years ago. You might ask your doc about just increasing the metformin and glipizide.
After using only diet and exercise the first 23 years, I was taking twice those amounts (up to max dosage) in addition to daily exercise a few years ago before starting on insulin 3 years ago.

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@grrranny

Thanks for the info. I noticed that the newer drugs also protect the kidney and heart, in fact AARP pointed out that some have even reversed kidney damage while also treating diabetes.
My doctor dropped my metformin dose from 2000 mg because the recommendations are for lower doses in the senior population.

Thanks again,
SD

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carbcounter | @carbcounter | 2 days ago

I'm not really informed on the drug tradeoffs, but trading the glipizide for a newer GLP-1 would seem likely.

So instead of that, what kind of dietary guidelines have you been following, both for the diabetes itself and for the related kidney disease? Perhaps there are some improvements possible there, too.

And for that matter exercise guidelines - which are no doubt more difficult due to the kidney disease.

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sad43 | @sad43 | 1 day ago

Regarding diet and exercise - within reason I follow guidelines to both. May even be excessive on the exercise side.

I am trying to learn if and what drug are currently recommended verses those recommended in 2000. There have been many new drugs some of which show promise to not only slow progression but to stop and even reverse these diseases.

Mayo Clinic says: "This medicine is not recommended in patients 80 years of age and older who have kidney problems."

Thanks for the feedback.

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