I have née taking achtyl L- carnitine for over a year

Google acetyl l carnitine and peripheral neuopathy

@jdiakiw
I am so glad that ALC is working for you!

There is research backing up the use of ALC for peripheral neuropathy.

Just a word of caution for those on thyroid meds, it is generally advised to avoid ALC if you have hypothyroidism. This is because it may potentially interfere with thyroid hormone activity.

With that caution,, here is a brief description of how ALC might work provided by ai mode summary of current research and standards:
"Unlike many medications that only mask pain, ALC targets the underlying causes of nerve damage.

Mitochondrial Energy Support: ALC transports long-chain fatty acids into the mitochondria to be burned for energy (beta-oxidation). This provides the "fuel" needed for damaged nerves to repair themselves.

Nerve Regeneration: It stimulates Nerve Growth Factor (NGF) and increases the density of nerve fibers in the skin, physically helping nerves grow back after injury.

Pain Signaling (Epigenetic Effect): ALC can "turn on" specific genes (mGlu2 receptors) in the spinal cord that reduce the release of glutamate, a primary chemical responsible for transmitting pain signals. This helps lower the overall "volume" of chronic pain.

Antioxidant Protection: It neutralizes reactive oxygen species and reduces oxidative stress, which is a major driver of nerve damage in conditions like diabetes."

Could you please tell us what brand you take and how much you take in a day?
I would really appreciate it. I have horrible neuropathy along with a lot of other issues with pain.
Thank you.

I just started taking it - I'd be interested in knowing the brand and dose too.

@lukekee i buy liquid diablo from amazon. flavourd. i take a tablespoon every day.

@jdiakiw
Thank you for the information. I will check it out.

Thanks for the info jdiakiw. For those who would rather take tabs or capsules, I have a subscription to consumerlab, which does third party testing of supplements. They do have a review of several acetyl l carnitine supplements that they have approved if anyone would like to know. They did not test any liquid formulas.

@jacqincalifornia
Please tell us the top ACL supplements as approved by Consumerlab.

@lukekee thank you I will check it out

Hi mcchesney - Approved based on having the amount of the active ingredient that the product claims to have (all are in capsule form):

Bluebonnet
Doctor's Best
GNC
Jarrow Formulas
Twinlab
Vitamin Shoppe

Sometimes a supplement in the list gets designated as a "Top Pick" but not in this case. All are designated "Approved"