I have a question to those of us using Lupron

@dpcarriere, I moved your question for Lupron users to the discussion you started earlier. I think participants in this discussion like @32fl @kujhawk1978 @norske46 @scullrower @upnort @landc @hergiew, no all of who experienced pain with Lupron.

Here are the questions @dpcarriere asked:
"(1) Does your level of pain have any correllation with your level of excercise?
(2) Do any of us receive different doses?"

PCa is short fir Prostate Cancer

kujhawk1978 nice data, very impressive - wish I could do that. You should be leading this group.

Clarification please - define PCa.

I have a question for Lupron users - heretofore to be known as users.

Do a self assessment.

(1) Does your level of pain have any correllation with your level of excercise?

(2) Do any of us receive different doses?

Input to me please.

I have been on Lupron for 4 years and I have low back pain and joint pain constantly, also chest pain. I also have a good friend who has suffered from depression and suicidal thoughts from it.

Also I had a knee replacement and they gave me opioids for pain and I had a severe reaction lost 40 lbs in 6 weeks it was not fun. I figured it out myself simply by looking up drug interaction with Lupron on the net number one drip interaction are opioids. I don’t know why an internal med Dr would not pick up on that.

When you look up Lipton on the there are many diadem affects to watch for.

I took Lupron for 25 months. About two-thirds of the way through that I told the urologist I was thinking of quitting Lupron because my legs were so weak. I have always been very athletic, running, walking and golfing. I had no energy in my legs at all. Every step was a strain. He would not let me quit. That was about three years ago and I still have tremendous weakness in my legs. My energy never returned. If I could do it again I would seek an alternative to Lupron.

I did 2 years of Lupron injections with no pain. Hot flashes and fatigue were my only side effects.

Get a new urologist. Best wishes.

Given the heterogeneous nature of PCa, there is a Loy of clinical data and personal choice that goes into a decision on if and how long one is on Lupron. In my case, we used triplet therapy, chemotherapy, radiation and a planned 24 months of ADT. We stopped the Lupron after 18 months given my response to the triplet therapy. There were studies pointing to 18 months as being just as effective as 36. The key I think is if the clinical data and your personal preferences support stopping treatment after a specific period and response, you must actively monitor through labs and consults with your medical team and have decision criteria about what constitutes a reason to go back on treatment and a decision point when to do so. For me, that criteria involves labs every 2-4 months, three or more PSA results that showed a continuous rise, PSA above .5, imaging that showed recurrence and then a decision to treat and with what, for how long...I am not a fan of "indefinite...! This chart shows my clinical history, it's been four years off treatment, I have actively monitored my PSA and seen my urologist, haven't met our decision criteria to resume treatment.

I don't think there is anything set in stone. It seems like they go for the longer duration to be on the safe side. But quality of life has to come into play and ultimately, we have to be our own judge of that. My urologist gave me one time fame to stay on Lupron and my radiologist suggested different. I went with what I thought would give me my best chance to have quality of life Best of luck