Concerned about the side effects of anastrozole
I completed all treatments for breast cancer but now I am supposed to take hormone blocker, named anastrozole. im concerned about the side effects. Has anyone here taken it and did anyone have hair loss?
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I reacted to fillers in one brand of generic anastrazole and then ditto Femara. I took brand name Femara for 5 years at great expense. For my last month I tried a different generic and did fine so I could have saved all that money 🙂 In general I do well with any med made by TEVA but there are other brands that work for me too.
I am working through a decision on whether or not to take any aromatase inhibitors and leaning toward skipping them. I've posted about my decision tree variables on another forum here so will spare readers
my angst and decision tree variables. i have the genetic marker for heart disease and high cholesterol and cannot tolerate statins. My cardiologist is excellent so we address what we can otherwise control. Someone on this forum mentioned a study suggesting AIs and reduced function. Here's a mention of that study (see below). If anyone is concerned, one can take an Endopat test to establish a baseline. I took one as part of a panel of tests as endothelial function relates to stroke risk and other cardio issues. The Endopat is non-invasive, no blood work needed.
"Aromatase Inhibitors Linked to Reduced Endothelial Function
Nalley, Catlin
Oncology Times: February 10, 2017 - Volume 39 - Issue 3 "
I forget where and who posted this, but someone mentioned doing great on a brand-name AI and later doing poorly (more and worse side effects) on the genetic version. Then switched back to the brand name and the negative side effects disappeared. That might be a more common situation than we realize. Has anyone else had this happen? I don't know much about generics except that they are not all of the same quality and are ranked by tier. If anyone has more information we could consider, please advise as I know there are a lot of diligent researchers on these boards. For which I am deeply grateful as a researcher myself by nature.
@luladavis do you know the name of the hormone shot that you receive along with anastrozole? It might be something very specific to your situation but I'd not heard of any hormone therapy along with anastrozole and am trying to learn as much as I can, being newly-diagnosed and comparing treatment options. Thanks in advance.
Thanks for info. I had no idea. I love learning new things so I can advocate for myself. Now a days you have to. Sounds like you are proactive in your health and are doing well and improving. Keep On Keeping On. 💪🏼
Thanks for sharing this! Sometimes it is good to hear from people who are not having issues with the medicine as a reminder.
I agree that this is probably from the Verzenio, I took tamoxifen for five and anastrazole for even more years. My cancer looks very similar to yours. My journey slightly different but not much, I am currently progression free. please come back and let me know how the biopsy goes? Did they order a PET scan yet?
Thank you for sharing. This is really good information!
I am in canada and the drugs that are covered by medical have fillers in them that make them cheaper to produce. If your onco asks for no fillers, it is purer but more expensive. The pure ones were easier to hamdle but the damage was already done for me. I am 68 and after struggling with the drugs, I opted for quality of life. It is working for me, but still do not have any flexibility in my hands and fingers. The drugs bring forward any underlying issues, which brought my arthritis in with a vengeance. That is my only struggle now, and the ability to move freely, clear mind and feeling of happiness was worth it to me. I will eventually get it again, but I want to live my life as a fulfilled person, not a labrat.
Took me a full year to get past the side effects. Good for you!! May we live the lives we hoped for in our retirement!! I now am doing the Starch Solution diet, which has helped me immensely. Pure foods and no cravings, and in the meantime have lost almost 50 pounds in 7 months. I am going to eat this way for one year, and then see where it takes me. My blood pressure was very high through the cancer treatment, but without drug, I have managed to get it to wonderful numbers!
Could it be the Verzenio causing the hair loss or could be the combination of both. I am 54 was on Tamoxifen 7.5 years, hit menopause and was switched to Anastrazole which I have been on for 1.5 years. Hair is thinning a lot but no bald spots or baldness yet. I have one more year to go on the Anastrazole but I was just diagnosed with a reoccurrence or a new cancer that is in my liver, abdomen, chest, rib, spine, sternum, fore arms and a tumor in my clavicle although I took the Tamoxifen and Anastrazole as directed to complete 10 years. I have a biopsy this week on 1/6/2022. My breast cancer was ER+ PR+ HER2+ aggressive, I had chemo, trial drug, double mastectomy and 35 radiation treatments in 2012 followed by Herceptin.