Trying to recover from a c. diff infection (Clostridium difficile)

Posted by acres @acres, Apr 12, 2016

I am trying to recover from a c.diff infection. This started with taking clindamycin in mid January and 3 days later I became ill with diarrhea and felt sick, loss of appetite etc...Went to the er twice, tested negative for c.diff on my 2nd visit. The Dr. told me to take imodium to rest my colon since I tested negative. That evening I had diarrhea and took the Imodium. Became constipated with pain lower right side. I went to a GI dr. pleading for help, I did another stool test and it came back positive for c.diff. I tried flagyl but could not tolerate the side effects. Tried vancomycin for 10 days. Did not work. Tested positive again, Went to a new gi doctor who prescribed dificid for ten days. I am 31 days post dificid and I have almost constant gut rumbling and urge to go. My 1st bm in the morning is usually semi normal, but after that they are always either pencil thin and or small pieces (2 to 5 times a day). This has been my routine since the vancomycin. I do not get dull blown diarrhea..... My dr. wants me to have a colonoscopy but I an scared that the cleansing will wipe out all my good flora. I currently take 2 florastor pills and 1/2 vsl3 per day. I eat fermented pickles for the probiotics as well..... I have many food intolerances since this whole mess began (fiber, many vegatables, dairy). I also have a strange taste in my mouth most of the time, have very little energy and fight with depression. My primary gave me Xanax .25 but I only take them at night when I cannot sleep...... Went to a nutritionist who put me on a no wheat, soy, dairy, gluten diet. Does not seem to be helping or hurting. I lost 20 pounds and cannot gain any weight (I weigh 120 at 5'7")... I am thinking it might be sibo, or candida but cannot find a dr. to test for these....I am in the right place for help or advice ? The urge to go is awful and limits my once active lifestyle.....
Thank you, Scott

Interested in more discussions like this? Go to the Digestive Health Support Group.

@vic83

Everyone hates the prep. It is a topic of conversation! But I found that the prep situation was "easier" this time. Before I recall they just said don't eat red meat. But this time they had me start a low fiber diet 7 days before with a one dose of Miralax. I think that kept too much from building up in colon. Two days before procedure only liquids with Ducolax added. Then night before 12 cups liquid and next morning 4 cups. The prep had a lemon flavor package with it so it really wasn't bad tasting. And my colon prep was scored with highest mark!

Jump to this post

I pointed out that my last two colonoscopies were only small non-cancerous polyps. Yet this week they found 3 precancerous ones, 2mm, 10mm and 12mm. Go figure. But if one has higher risk profile, there is never certainty. I suspect also that already having a different cancer is an added risk factor, because cancer also indicates a weaker immune system.

REPLY
@pb50

I’m undecided. I’m 74 and my last two colonoscopies have been normal - the one 5 yrs ago had 2 polyps but were benign. The one last year showed no polyps but did confirm dx of microscopic colitis. They said I could discontinue for purpose of screening for colon cancer. I hate the prep. I mean I really really hate it. So it will be a game time decision 🙂

Jump to this post

Everyone hates the prep. It is a topic of conversation! But I found that the prep situation was "easier" this time. Before I recall they just said don't eat red meat. But this time they had me start a low fiber diet 7 days before with a one dose of Miralax. I think that kept too much from building up in colon. Two days before procedure only liquids with Ducolax added. Then night before 12 cups liquid and next morning 4 cups. The prep had a lemon flavor package with it so it really wasn't bad tasting. And my colon prep was scored with highest mark!

REPLY
@researchmaven

So the age of 75 that I seemed to find more than once in the Google-verse is perhaps an average, guesstimate or something else.

I can only aspire to be on top of things like you are. Bravo!

I also can't help thinking that when things get really complex for me health-wise, I need to head to a top facility like Mayo.

I appreciate hearing back from you!

Jump to this post

Screening guidelines have changed over the years, and they now even start at an earlier age.
Key is the risk factor. People who have family members with a history of polyps, or colon cancer are considered at higher risk and should be sure to get colonoscopies.
And having precancerous polyps means one should really stay on top of it!!!!

REPLY

I’m undecided. I’m 74 and my last two colonoscopies have been normal - the one 5 yrs ago had 2 polyps but were benign. The one last year showed no polyps but did confirm dx of microscopic colitis. They said I could discontinue for purpose of screening for colon cancer. I hate the prep. I mean I really really hate it. So it will be a game time decision 🙂

REPLY
@vic83

I am 82! And Mayo just told me to come back in 3 years. I will be 85. The Guidelines on when to come back are based on what they find.
I first did consult at Mayo to see if the risk vs reward given my polyp history in 4 previous colonoscopies and my new health issues warranted doing my five-year surveillance colonoscopy. They reviewed everything and noted I had a history of advanced neoplasia (in 2010 - two 10mm precancerous polyps). I was therefore scheduled for colonoscopy in hospital (given my age and breathing issues - other places also send elderly to hospital).
I was shocked that they found and removed three precancerous polyps each a different type and one was 12mm tubulovillous adenomas (20% to 25% harbor a malignancy).
I have multifocal lung cancer which can be managed, and one can live many years ....so I do not want another cancer which could also compromise my treatment options for my existing cancer. I tell my doctors to think strategically. I don't want to be locked into something because of the wrong choice. For example, I discovered I had a heart problem when I found out I had lung cancer. If they had put in a stent first, I would have had to take Plavix for 6 months to a year and then I would not have been able to do my lung surgery. Luckily, I knew about the need to take Plavix for stents and on the table when the Cardiologist shouted "blockage" I said "and what about my lung biopsy appointment?" So they immediately responded "we can medicate" and four weeks later I had lung surgery which found and removed a stage 1b cancer! "b" because it was bigger! Who waits on that????
And four months later I did the stent.

Jump to this post

So the age of 75 that I seemed to find more than once in the Google-verse is perhaps an average, guesstimate or something else.

I can only aspire to be on top of things like you are. Bravo!

I also can't help thinking that when things get really complex for me health-wise, I need to head to a top facility like Mayo.

I appreciate hearing back from you!

REPLY
@researchmaven

Are you 75 years or older? If not, will you continue colonoscopies after age 75?

Jump to this post

I am 82! And Mayo just told me to come back in 3 years. I will be 85. The Guidelines on when to come back are based on what they find.
I first did consult at Mayo to see if the risk vs reward given my polyp history in 4 previous colonoscopies and my new health issues warranted doing my five-year surveillance colonoscopy. They reviewed everything and noted I had a history of advanced neoplasia (in 2010 - two 10mm precancerous polyps). I was therefore scheduled for colonoscopy in hospital (given my age and breathing issues - other places also send elderly to hospital).
I was shocked that they found and removed three precancerous polyps each a different type and one was 12mm tubulovillous adenomas (20% to 25% harbor a malignancy).
I have multifocal lung cancer which can be managed, and one can live many years ....so I do not want another cancer which could also compromise my treatment options for my existing cancer. I tell my doctors to think strategically. I don't want to be locked into something because of the wrong choice. For example, I discovered I had a heart problem when I found out I had lung cancer. If they had put in a stent first, I would have had to take Plavix for 6 months to a year and then I would not have been able to do my lung surgery. Luckily, I knew about the need to take Plavix for stents and on the table when the Cardiologist shouted "blockage" I said "and what about my lung biopsy appointment?" So they immediately responded "we can medicate" and four weeks later I had lung surgery which found and removed a stage 1b cancer! "b" because it was bigger! Who waits on that????
And four months later I did the stent.

REPLY

I had cdiff from december came back twice on vanco 4 weeks, dificid, 2 weeks, still positive. i did get the VOWST,the fecal transplant drug, so far its been 2 weeks and I tested negative, but still have diahrea, sometimes watery, but more like greenish color mug or strips of dirty rag. The smell is putrid. Im nausiated and also pain in the lower right. Im trying to get to another gi expert in NY to see. Perhaps you can try the Vowst. Ask your GI.
I feel for you, You cant go anywhere unless you have a toilet bowl under you. My doctors are puzzled why like you the right lower pain. and nausea. Take some pedialyte or gatorade so you dont dehydrate. Good luck to you. You all are in my prayers. This is the pits. Cdiff

REPLY
@vic83

That is so interesting. I just had a colonoscopy at Mayo and the GI besides removing polyps also noted that mucous was granular so he took biopsies throughout the entire colon for possible microscopic colitis. Fortunately I was negative for it.
And what I now tell everyone is that even if you are near "aging out" from colonoscopies, do them!!! In 2010 I had 2 10mm precancerous polyps, but in 2013 and 2018 I only had 1 and 2 polyps found and they were not precancerous. So that period was eight years and no cancerous polyps.
Then in 2024 - 14 years from 2010 and 5+ years from last colonoscopy, they find 3 polyps - each a different type and all precancerous!!! And one even 12mm!!!

Am also impressed that Bactrim caused you C-diff as I have been given it more than once with the statement that it is relatively safe.

Jump to this post

Are you 75 years or older? If not, will you continue colonoscopies after age 75?

REPLY

Get the colonoscopy. You may have microscopic colitis and they can only diagnosis with random biopsies from colon.

REPLY
@vic83

That is so interesting. I just had a colonoscopy at Mayo and the GI besides removing polyps also noted that mucous was granular so he took biopsies throughout the entire colon for possible microscopic colitis. Fortunately I was negative for it.
And what I now tell everyone is that even if you are near "aging out" from colonoscopies, do them!!! In 2010 I had 2 10mm precancerous polyps, but in 2013 and 2018 I only had 1 and 2 polyps found and they were not precancerous. So that period was eight years and no cancerous polyps.
Then in 2024 - 14 years from 2010 and 5+ years from last colonoscopy, they find 3 polyps - each a different type and all precancerous!!! And one even 12mm!!!

Am also impressed that Bactrim caused you C-diff as I have been given it more than once with the statement that it is relatively safe.

Jump to this post

I’ve had it before myself. But this time was different for unknown reasons. Perhaps because my colon was so inflamed at that point.

REPLY
Please sign in or register to post a reply.