Tymlos Experience - Can it mitigate my hip pain?

Posted by sewingsmb @sewingsmb, Oct 11 2:13pm

I am in my second month of Tymlos with no negative reaction. My doctor did no tests before prescribing Tymlos. Can Tymlos. mitigate some of the hip pain I suffer? The doctor indicated that a hip fracture at my age of 87 would probably be a death knell.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

windyshores | @windyshores | Oct 11 3:44pm

@sewingsmb have you been told you have osteoarthritis in your hip?

sewingsmb | @sewingsmb | Oct 11 5:54pm

I have osteoporosis, probably the same as arthritis. I've had two knee replacements due to arthritis.
Thanks,
Sandra

windyshores | @windyshores | Oct 11 8:04pm

In reply to @sewingsmb "I have osteoporosis, probably the same as arthritis. I've had two knee replacements due to arthritis...." + (show)

@sewingsmb as you probably know, osteoporosis and osteoarthritis are very different. I asked because Tymlos may help with healing osteoporotic fractures, I was told, but not sure if it has any effect on pain from osteoarthritis. Sorry you have pain!

gently | @gently | Oct 12 3:59pm

@windyshores,
I'd thought that the advantages of abloparatide would be at least equal to those of teriparatide. https://www.sciencedirect.com/science/article/pii/S2214031X22001279
I'd like to know your thoughts.

windyshores | @windyshores | Oct 12 4:12pm

In reply to @gently "@windyshores, I'd thought that the advantages of abloparatide would be at least equal to those of..." + (show)

@gently I would think Tymlos would be equal to Forteo in helping osteoarthritis in the right conditions. Thanks for posting that. As I wrote, I didn't know. Mabye this is why I felt so much better on Tymlos!

From the link:

"5. Conclusion
In summary, we conclude that the PTH (1–34) effectively prevents KOA progression by alleviating degeneration of cartilage and ameliorating abnormal remodeling of SCB. The cartilage and SCB were alleviated in the WT mice, but the effect of cartilage-protection observed well in the OPG−/− mice. This implies that the PTH (1–34) may play excellent therapeutic role depends on the OPG in the SCB but not depend on the OPG in the cartilage. Moreover, the chondro-regenerative and chondro-protective characteristic features were well confirmed in vitro. The current study provides evidence that the PTH (1–34) might be a promising and potential medication for KOA."