How fast does PSA drop after RARP

Posted by someoneelse @someoneelse, 4 days ago

I had the RARP procedure done Tuesday morning and my doctor wants me to get a PSA test prior to my catheter removal this next Tuesday.

My PSA was 9.85 shortly before the procedure. Surely 7 days isn't enough for my PSA to drop as much as it will?

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I’ve never heard of a PSA test done that quick. Someone actually asked this question a few months ago and no one had a PSA test done less than five or six weeks. Mine was done seven weeks after my prostatectomy.

At that point, it should be undetectable. Not sure about getting it so soon. If you do a check of AI you will find they say it should be 4 to 6 weeks, at least, before the test is done.

Is your doctor worried he left tissue After the surgery? That fast a PSA is really weird, and definitely unreliable.

Did you ask him why since it is not a standard of care?

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My first psa test after RARP was at 12 weeks as ordered by the CCOE where I had it done. And that's even with cribriform and IDC showing up on the pathology report. That said, I'd comply since the doctor asked for it since it's so simple a test. Please let us know if you find out why. Best wishes.

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Profile picture for jeff Marchi @jeffmarc

I’ve never heard of a PSA test done that quick. Someone actually asked this question a few months ago and no one had a PSA test done less than five or six weeks. Mine was done seven weeks after my prostatectomy.

At that point, it should be undetectable. Not sure about getting it so soon. If you do a check of AI you will find they say it should be 4 to 6 weeks, at least, before the test is done.

Is your doctor worried he left tissue After the surgery? That fast a PSA is really weird, and definitely unreliable.

Did you ask him why since it is not a standard of care?

Jump to this post

@jeffmarc

Yes, it is highly unusual and I am wondering if doctor mixed up dates by accident , or something ?

There could be no possible reason to do PSA at 7 days. His PSA ,in the best case scenario, will be about 2.4 or little bit less. For 9.85 to become undetectable (0.01) he will need at least 4 weeks.

Maybe his doctor wants to see the trend of some sort ?

Our PSA test was scheduled for 12 weeks post op. but we could not wait to see results so we tested it at 7 weeks in a local lab.

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I'm with the rest of the group here, just for kicks, if my excel fooo is good....

In 7 days you should expect something like 1.85

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Thanks for your comments guys. It did turn out to be a typo. They want me to wait 60 days for first PSA test.

Its nice to have you all to bounce my thoughts and ideas off of!

Thanks again...

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That sounds better, it was 6 weeks post op before I had my first test.

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My 1st post-op PSA was 90 days after RP. Treated at Johns Hopkins.
My understanding is that it takes some time for a reliable PSA and while waiting is hard, a misleadingly high (or low?) PSA would have been disconcerting.
Best wishes.

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Profile picture for jeff Marchi @jeffmarc

I’ve never heard of a PSA test done that quick. Someone actually asked this question a few months ago and no one had a PSA test done less than five or six weeks. Mine was done seven weeks after my prostatectomy.

At that point, it should be undetectable. Not sure about getting it so soon. If you do a check of AI you will find they say it should be 4 to 6 weeks, at least, before the test is done.

Is your doctor worried he left tissue After the surgery? That fast a PSA is really weird, and definitely unreliable.

Did you ask him why since it is not a standard of care?

Jump to this post

@jeffmarc

I agree: ordering a PSA test before cathether removal is very unusual and does not make sense since it will take many more weeks for the baseline PSA level to go down. My surgeon ordered a PSA test from 8 to 10 weeks after surgery, and I plan to have mine taken abott 9 weeks after my surgery.

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