Have you ever had hiccups with or after chemotherapy?

We all know what hiccups are, right? They are involuntary contractions of the diaphragm — the muscle that separates your chest from your abdomen and plays an important role in breathing. Each contraction is followed by a sudden closure of your vocal cords, which produces the characteristic "hic" sound.

Mayo Clinic investigators want to learn more about hiccups in people who are receiving cancer treatment and, if you have experienced hiccups, how they may have affected your quality of life.

So, whether you’ve had hiccups or not, we asked Connect members to take part in a survey. Responses in the survey remain anonymous and are kept completely confidential. The survey is now closed. I will share the results of survey after analysis.
In the meantime, feel free to take part in this discussion about hiccups, if you want to share.

Have you had hiccups after chemotherapy? If yes, were they different than you’ve experienced before? Did they bother you or affect your daily living?

+++Study Results+++
Frequency and Symptomatology of Hiccups in Patients With Cancer: Using an On-Line Medical Community to Better Understand the Patient Experience
By C Ehret, C Young, C Ellefson, L Aase, A Jatoi
Published April 1, 2021
https://doi.org/10.1177/10499091211006923

Interested in more discussions like this? Go to the Cancer: Managing Symptoms Support Group.

Profile picture for philv @philv

I am at chemo #6. I get the hiccups for a few days. Then they go away.

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Occasionally I get hiccups it all started after session #5
Not real bad,but noticeable.

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Profile picture for Colleen Young, Connect Director @colleenyoung

@susu2 @odette @merpreb, thanks for sharing your experiences.

Susu, technically speaking hiccups are involuntary contractions of the diaphragm. Hiccups are usually repetitive. Belching or burping (eructation) is the voluntary or involuntary, sometimes noisy release of air (gas) from the stomach or esophagus through the mouth. Knowing that distinction, can you tell if you're experiencing burps or hiccups?

Merry, that's what we are trying to find out -- whether hiccups may be related to treatment and if yes, which treatments?

Odette, good question. On the grand scale of cancer treatment side effects, we want to find out if hiccups are a side effect and if yes, how they affect daily living. This study will help us understand if further research is necessary to understand how patients manage this side effect if it is having a negative impact on quality of life.

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I found that it was not the chemo but the Meds that are making you hiccup I quit taking the meds

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My daughter found a discussion online that said the drug Baclofen works for chemo related hiccups. I had used this medication just months ago for severe back spasms. So during my hubby's hiccups I gave him one an poof gone. So chemo morning an the next 3 days he gets a Baclofen. His Dr prescribed them for him. Good luck!

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I am at chemo #6. I get the hiccups for a few days. Then they go away.

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Profile picture for Colleen Young, Connect Director @colleenyoung

Hi Chris, thank goodness that your hiccups stop after a while. Do they only happen when you eat? Are there particular foods that trigger the hiccups?

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The hiccups start with all kind of food, not when I drink. I think it's a bit more with dry food like toasts, barley crackers and breadsticks. But I noticed that it's gradualy fading. Hoping that it'll stop after a few weeks?

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Profile picture for chrisoula @chrisoula

Hi Colleen, I'm Chrissoula and I was diagnosed with HER2+ last year, stage 3A. I had mastectomy & lympectomy (21 removed - 9 affected) and chemotherapy (TCHP) from 24/11/2021 till 22/4/2022 (weekly), then I had radiation for 25 sessions and now continuing with immunotherapy (Paclitaxel - Herceptin) till it's a full year since I begun. I'm having hiccups but I'm not sure when it started. I think it has started after I've finished radiation, mid June, though I think I had before but not so frequently. But then when I had chemo and with radiation I didn't eat really much, mostly I drank soups, hot tea and soft food easy to swallow, that's why I lost 15 kgr! That's one good think that happened, 'cause I really wanted to lose them for a long time!!! It starts with the first bite that comes in my mouth. I thought that I was eating fast, so I tried to eat slower but it doesn't work, I still get the hiccups. It is not so bothering since it stops after a while, but I thought it was strange because I didn't have hiccups so frequently before!

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Hi Chris, thank goodness that your hiccups stop after a while. Do they only happen when you eat? Are there particular foods that trigger the hiccups?

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Profile picture for sonshine161 @sonshine161

I’ve had hiccups and belching since i started chemo/immuno. No radiation. I think it’s the drugs messing with my lungs and everything else. Seems like it comes and goes

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Hello @sonshine161 and welcome to Mayo Connect. I appreciate you sharing your experiences with others on Connect. You say this, "comes and goes." Is there a certain time period when it happens after chemo? Were you told that this might be a side effect of this particular type of chemo?

May I ask what type of cancer is being treated?

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Hi Colleen, I'm Chrissoula and I was diagnosed with HER2+ last year, stage 3A. I had mastectomy & lympectomy (21 removed - 9 affected) and chemotherapy (TCHP) from 24/11/2021 till 22/4/2022 (weekly), then I had radiation for 25 sessions and now continuing with immunotherapy (Paclitaxel - Herceptin) till it's a full year since I begun. I'm having hiccups but I'm not sure when it started. I think it has started after I've finished radiation, mid June, though I think I had before but not so frequently. But then when I had chemo and with radiation I didn't eat really much, mostly I drank soups, hot tea and soft food easy to swallow, that's why I lost 15 kgr! That's one good think that happened, 'cause I really wanted to lose them for a long time!!! It starts with the first bite that comes in my mouth. I thought that I was eating fast, so I tried to eat slower but it doesn't work, I still get the hiccups. It is not so bothering since it stops after a while, but I thought it was strange because I didn't have hiccups so frequently before!

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I’ve had hiccups and belching since i started chemo/immuno. No radiation. I think it’s the drugs messing with my lungs and everything else. Seems like it comes and goes

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Hoping all works out well. Mayo is a good place.

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