Colestipol for symptoms of IBS-D

Posted by richannc @richannc, Nov 8, 2017

Has anyone had any experience with talking colestipol for treating the recurring diarrhea that is part of the IBS-D syndrome? My gastro prescribed it and it does seem to minimize diarrhea if taken twice a day. I would appreciate hearing form anyone who has tried it.

AC

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Profile picture for gboi @gboi

Thanks for filling in some of the details. I am not familiar with the use of colestipol to manage a removed/damaged gall bladder but this is certainly one of its legitimate uses. To what extent have you played around with dose and timing of the medication? Generally speaking, people have most success with it when taken with the meals that contain the most fats, and usually no sooner than the first bite of food but some find it more effective up to 45 minutes after eating concludes. If you have not already, consider diligently tracking what and when you eat, and when you took colestipol, and see if you can at least move the needle towards something better than your current situation. Last, have you spoken to your doctor about these symptoms? He or she may have some advice on things that we have overlooked. Good luck.

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I usually take Colestipol about 15 minutes before I eat, but usually have to go about 15 to 30 minutes afterward, so not sure what would happen if I did not take it until 45 minutes after. I cannot really track any one thing that I eat with my problem, because in the morning even when I have just a bagel or toast, my problem still exists. I intend on calling my doctor again and see what she suggests.

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Profile picture for pohl @pohl

I have been using colestipol for about 3 months and it has not helped my diarrhea that much. I still have to be very careful in the morning after I eat. I usually do not eat lunch, because I am still afraid to go out because not sure when it will come on.

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So sorry it hear about this debilitating issue…fortunately I don’t have this problem. (I have my share of others, which is why I’m on this site) as to the urinary tract infections, I’ve had my share. I don’t know if this is an issue connected to you Your age and

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Profile picture for pohl @pohl

I have been using colestipol for about 3 months and it has not helped my diarrhea that much. I still have to be very careful in the morning after I eat. I usually do not eat lunch, because I am still afraid to go out because not sure when it will come on.

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Sent too soon…
Your age could have something to do with uti’s, hormone loss. See a urologist-thinking you are female, if so, they can possibly prescribe a vaginal cream or tablet to replace not just lost hormones and moisture in your vagina, but helps to keep your urethra “young”.
Stress is a huge factor in the tightness of your urethra, which prevents complete emptying. There are meds for relaxing that area, that you may or may not be able to take, but I would check. There are also quick doctor treatments to open the urethra, if that is the problem.
Also, check with your doc as to where you could you could find info online or in person on how to calm your mind and hopefully reduce your stress. I tried hypnosis-amazing!
Previous post suggested playing with the time to take your meds, I think that is a good idea…can’t get worse? 🥴
Good luck!!’

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Cholestipol seems to help (2 x day 1 Gm tablet), but my bottom is so sore. I usually have BM's daily (most times in morning, but food has become my enemy especially evening meal. After eating about 5:30 pm I get a constipated feeling and lots of gas, and can't go until following morning. I also have hemorrhoids which is very uncomforable. I feel like I can't travel as the motion seems to make diarrhea worse. Anyone having issues like this. Have not been able to get appointment at Mayo and told to call monthly. Have seen GI specialists for over 30 years.

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Profile picture for cordelia @cordelia

Cholestipol seems to help (2 x day 1 Gm tablet), but my bottom is so sore. I usually have BM's daily (most times in morning, but food has become my enemy especially evening meal. After eating about 5:30 pm I get a constipated feeling and lots of gas, and can't go until following morning. I also have hemorrhoids which is very uncomforable. I feel like I can't travel as the motion seems to make diarrhea worse. Anyone having issues like this. Have not been able to get appointment at Mayo and told to call monthly. Have seen GI specialists for over 30 years.

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I have crohne's. And severe diarrhea. I take a whole lot of Timonium each day, per Dr's suggestion. So far seems to be the only thing that helps. Took 4 Dr's to even come up with that suggestion. For the hurt bottom, as humiliating as I find this whole disease, at its worse cover yourself with a thick layer of petroleum jelly. It's been harmless so far. I feel for you. I cannot stand any part of this digestive disease. I don't see myself getting anymore humiliated than what I go through with it. For me, I believe it was the removal of my ileum during my 3 way resection in 2017. It always leaves me wondering when's the food come out! Its like turning on a water faucet!

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Profile picture for cordelia @cordelia

Cholestipol seems to help (2 x day 1 Gm tablet), but my bottom is so sore. I usually have BM's daily (most times in morning, but food has become my enemy especially evening meal. After eating about 5:30 pm I get a constipated feeling and lots of gas, and can't go until following morning. I also have hemorrhoids which is very uncomforable. I feel like I can't travel as the motion seems to make diarrhea worse. Anyone having issues like this. Have not been able to get appointment at Mayo and told to call monthly. Have seen GI specialists for over 30 years.

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I really feel for you, having so many of the same symptoms. Good to feel “less alone” with these issues with the help of support groups. The one thing that has helped the diarrhea issue for me is mixing 1-2 T pure psyllium with warm water every morning and taking a probiotic with that. Have you tried zinc oxide ointment for your bottom? Occasional use of 1% hydrocortisone cream has helped me, too. My biggest problem now is lots of bloating and gas, mostly after dinner, like you. So uncomfortable (and embarrassing!). Good luck on this journey. Hoping and praying for healing solutions.

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Profile picture for cordelia @cordelia

Cholestipol seems to help (2 x day 1 Gm tablet), but my bottom is so sore. I usually have BM's daily (most times in morning, but food has become my enemy especially evening meal. After eating about 5:30 pm I get a constipated feeling and lots of gas, and can't go until following morning. I also have hemorrhoids which is very uncomforable. I feel like I can't travel as the motion seems to make diarrhea worse. Anyone having issues like this. Have not been able to get appointment at Mayo and told to call monthly. Have seen GI specialists for over 30 years.

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I was just put on Colesevelam twice a day in pill form. I just started last Friday. I think it's working but you can't have caffeine or Vitamin D. I am low on D so will have to check with my gastro on that. I guess I will have to take it awhile to see if it slows down my constant need to go. Diagnosed with IBS-D forty years ago. Cutting out gluten has helped somewhat. Traveling next month from California to Savannah GA for a family vacation and it's always worse when traveling. Always have to have an isle seat on the plane. It's not only uncomfortable it's an embarrassing condition.

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Profile picture for cordelia @cordelia

Cholestipol seems to help (2 x day 1 Gm tablet), but my bottom is so sore. I usually have BM's daily (most times in morning, but food has become my enemy especially evening meal. After eating about 5:30 pm I get a constipated feeling and lots of gas, and can't go until following morning. I also have hemorrhoids which is very uncomforable. I feel like I can't travel as the motion seems to make diarrhea worse. Anyone having issues like this. Have not been able to get appointment at Mayo and told to call monthly. Have seen GI specialists for over 30 years.

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I have almost the exact problem. Tried Colestipol & it didn’t help. Was up all night back and forth to bathroom. We haven’t found anybody who knows how to help. If you find something please share.

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Profile picture for cordelia @cordelia

Cholestipol seems to help (2 x day 1 Gm tablet), but my bottom is so sore. I usually have BM's daily (most times in morning, but food has become my enemy especially evening meal. After eating about 5:30 pm I get a constipated feeling and lots of gas, and can't go until following morning. I also have hemorrhoids which is very uncomforable. I feel like I can't travel as the motion seems to make diarrhea worse. Anyone having issues like this. Have not been able to get appointment at Mayo and told to call monthly. Have seen GI specialists for over 30 years.

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Hi I’ve been feeling very bad last 4 days I even went to the emergency room and did blood. Work , ct scan and cray of abdomen and chest I started feeling chills , fatigue , dizziness and a weird pressure middle of chest and waking up middle of the night can’t breath well can someone help me please I did labs and everything came back negative doctor told me is just a viral virus

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Profile picture for kbswartz @kbswartz

I have almost the exact problem. Tried Colestipol & it didn’t help. Was up all night back and forth to bathroom. We haven’t found anybody who knows how to help. If you find something please share.

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It's been a week since starting Colestipol and yesterday I went 5 times in 11 hours so I don't know if it is working. I was also trying it to lower my cholesterol because I can't take any regular statins and I've tried them all. I also just read that Colestipol raises your triglycerides and mine
are already high. It's just a constant fight.

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