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jlfisher56
@jlfisher56

Posts: 64
Joined: May 02, 2017

GERD, gastroparesis, neurogenic bowel

Posted by @jlfisher56, May 7, 2017

I have had problems similar to so many GI people. The swallowing problems (food stuck in the throat, bloating, nausea, feeling like choking, “fullness” for hours). Finally after many upper and lower scopes ( have 18 cm colon left and function 80% well when cervical neck is well), a small hiatal hernia, numerous different PPI’s for stomach changes, reflux, etc. and now on Nexium, the finding out the main problem 6 years ago was gastroparesis caused by a pain medication. Instead of a pacemaker, I tried a “newly” approved drug for the pyloric muscle of the lower stomach, botox, placed in 3 places to keep the muscle open a little so food could continually be released into the small intestine. The erythromycin in a low dose is a prokinetic, making the nerves contract the stomach muscles but, wasn’t working. Still use 4x/day. This way no food collected in the stomach being able to “rot” causing sepsis, and decreased daily nausea and vomiting. I still can only eat small amounts and is more liquid or soft medicine/foods. My appetite isn’t the best. I often have reflux, bloating, constipation and hoarseness. But it has been 3 yrs since botox to my stomach and it is working. I take my blessing where I can. I hope this helpe others.
Also, my diet had to change to rapidly digesting foods like white bread and not the “good” eating I was doing like whole wheat or 21 grain bread ( was laying on my stomach for hours), plus many vegetables and also many raw vegetables…a no no.
My daughter is going through so much of this and is an RN. Has Barrett’s esophagitis, hiatal hernia, dysplasia, leaky gut syndrome i.e. and awaiting biopsies. Constant n/v, bloating,hoarseness, food in the throat like you in the chat.She is also an RN. On many “new” meds again.
It really can get to you especially when you work and have a very busy life like she does.
My best to all. Hope I could help someone.I understand your frustrations. It is wonderful having an understanding doctor that listens!

Joan

REPLY

Has anyone had experience with using the drug Domperidone for chronic nausea?

Hi @jacque6977,

As you probably know, Domperidone is not available in the United States, but it is widely used in other countries; for example, whenever I visit family in Bombay, India, Domperidone is what we take for nausea or even queasiness.

Although not for chronic nausea, @emeleen @konagirl have discussed taking Domperidone, for digestive issues, and I hope they will return to share their
experience.

@jacque6977, do you have a specific question regarding this drug?

@kanaazpereira

Hi @jacque6977,

As you probably know, Domperidone is not available in the United States, but it is widely used in other countries; for example, whenever I visit family in Bombay, India, Domperidone is what we take for nausea or even queasiness.

Although not for chronic nausea, @emeleen @konagirl have discussed taking Domperidone, for digestive issues, and I hope they will return to share their
experience.

@jacque6977, do you have a specific question regarding this drug?

Jump to this post

For four years the medical profession has been unable to diagnose the cause of my wife’s chronic nausea and fatigue. Domperidone is being given to her for a ten day trial. I realize the drug is not available in the US, but it can be purchased in Canada.

@kanaazpereira

Hi @jacque6977,

As you probably know, Domperidone is not available in the United States, but it is widely used in other countries; for example, whenever I visit family in Bombay, India, Domperidone is what we take for nausea or even queasiness.

Although not for chronic nausea, @emeleen @konagirl have discussed taking Domperidone, for digestive issues, and I hope they will return to share their
experience.

@jacque6977, do you have a specific question regarding this drug?

Jump to this post

I tried it in 2009 and paid $34.00 month. It was becoming costly with my other medications and not covered under US Health insurances. It did work but my EES works just as well and is covered. A friend of mine “finally” was diagnosed with gastroparesis (felt she had it for years), and was placed on domperidone but shouldn’t have. First, it is from Canada (not under our FDA and technically we are not to buy across country lines…even though used in Europe and Canada about 30 yrs and very good) but her cost is $700/month and her friend’s at the pharmacy I used, is now up to $500/month she said. My friend is elderly and has a cardiac pacemaker, tears in her aortic arch and congestive heart failure. All “NO’s” for domperidone’s usage. She did not get a paper with side effects but, her daughters and I looked on the computer and she was shocked. My brother-in-law had 2 pharmacies that compounded it locally for him (they did it for years) but they discontinued doing it. He now obtains it from Canada and does help him a lot like it did for me. I do not remember his cost but I don’t believe it was that high. I could be mistaken. The USA should manufacture it.

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