Gabapentin for rapid gastric emptying, diarrhea and possible Cdiff

@celderki07,
I know it has to be quite tough to feel like you can't even leave the house because of your bowels.

There is some research that suggests that Gabapentin does help with reducing rectal mechanosensitivity and increases compliance in patients with diarrhea-predominant irritable bowels.

Here are a couple of sites that I found to show you some data:
https://pubmed.ncbi.nlm.nih.gov/16268973/#:~:text=Conclusion%3A%20Our%20results%20show%20that,bowel%20syndrome%20patients%20warrants%20investigation.
https://www.karger.com/article/fulltext/362405
How long have you been dealing with this?

Thank you. It’s been 3 years now. I also have cdiff toxins which I’m not sure if I need to treat or if it’s just post infectious IBS I’m dealing with.

My GDH antigen stool test came back “detected” but toxins negative. Indeterminate. But pcr says toxin B detected. Should I treat? I have horrible diarrhea and urgency everyday but not sure if it’s just post infectious IBS im dealing with. I’m scared whether to do vancomycin again and FMT if it fails.

I HAD A IMPACTED RECTUM ABOUT A MONTH AGO NOW I HAVE HERNIA ON BOOTH SIDE OF GROIN. COULD THE HERNIA S BE BECAUSE I WAS IMPACTED

Hi @celderki07,

You'll see that I moved your last post to your previous discussion that you started and adjusted the title to include Cdiff since we started talking about that as well. I did this because I want the members to be ale to see your whole story without having to search for different conversations.
There are many people on Connect that have dealt with Cdiff and I would like to introduce you to them so you can connect and possible learn about what they dealt with as well
@ngorman25, @losthope, @pines, @lacy2, @mhi, @dilly69, @cece55 and @danab have all experienced Cdiff.

When your primary detected the toxin, did they suggest that you treat it or just watch for symptoms?

So sorry you are dealing with Cdiff. In my case when they detected the toxin they started me on Vancomycin. And had a relapse and another round of antibiotic. My body didn’t feel right and felt that c Diff was coming back so I went and worked with a Naturopathic doctor because I refused to keep taking antibiotics. The naturopathic doctor put me on herbal antimicrobial for a month along with other things like GI revive to heal my gut. I took lots of probiotics and S Boulardii was a game changer. I was taking saccharomyces boulardii three days per day. When I got tested after c Diff was gone but still felt awful lots of loose stools per day they diagnosed me with post infection IBS. Saw a nutritionist that started me on a low FODMAP diet for 6 weeks and slowly introduced food back. It took me a full year to start feeling like human again but I still take probiotics to this day and stopped the S Boulardii now. Hope this helps please ask away. This is something when you learn about you will be able to fight. I bought as well Michelle Moore’s book on c Diff. Google her it was a great book that taught me a lot. Wishing you a speedy recovery. God bless

I didn't get diagnosed for a month and then they gave my flagel which l was allergic to. Platelets dropped to 80 and was very sick. Vancomycin was much better; but honestly it was the S Boulardii that turned me around.

Are you saying that Gabapentin helps with IBS? Or makes it far worse? I have read numerous articles about Gabapentin causing terrible diarrhea for many patients.

Hello. I have been battling colon issues for many months started with diverticulitis with a perforation ended up in the hospital on massive antibiotics for a week sent home on more antibiotics triggering cdiff since July. I’ve been on the metronidozole, vacomyacin three times and most recently the dificid and seems isn’t gone sadly. I see a wellness specialist and he’s had me on a variety of supplements thus far not much progress. One of the probiotics he sometimes has me on includes the one you mention but it’s not the only ingredient and he only has me on it when I’m on the cdiff antibiotic. You mention you took it three times a day. Can you tell me what brand and what dosage you took along with how long you were on it (weeks or months?). I may need to seek a contagious disease specialist and may require fecal transplant. Hoping to find an option to get rid of this so frustrating. Thank you!

Sorry you are going through this what an awful thing. I took S Boulardii either AOR brand or designs for Health they are both good. Take the S Boulardii along with the antibiotic but make sure to take them 3 hours apart so the antibiotic doesn’t kill the probiotic. Good luck on your journey and please ask away any questions you may have.