Fatigue

Hi
I am 15 months post-op from stopping radiation treatment for breast cancer. 3 months ago I felt like my fatigue was lifting since starting Zoloft 25 mg. Now I've got fatigue back and feeling like I am depressed again and having some anxiety. I am going to 50 mg of Zoloft which I really didn't want to but I'm going to try it and see if it helps. Has anyone else had this issue with the fatigue and the depression and anxiety I know that it's from being taken off my hormones which I loved being on but I guess this is the way it is now. Also wondering when all these doctor's appointments will ever end it gets very depressing when you spend nine days out of the month out appointments.