Failed (or impaired) gastric accommodation, with functional dyspepsia

Posted by cindy1952 @cindy1952, Jun 24 6:39pm

Stomach has problem relaxing and expanding to accommodate meals. Food and calorie intake are limited, which leads to unintentional weight loss. Am down to 100 lbs. Have been prescribed Buspar (buspirone). Symptoms can include early satiety, upper abdominal pain, chest discomfort, belching. Have to eat smaller amounts more frequently, eat very slowly. Brain-gut connections, vagus nerve, or serotonin levels may be involved? I'm told this is a chronic problem, and I have had it more than once before. Symptoms can be variable and unpredictable, and sometimes have decreased to very little. When they increase greatly, there's usually some sort of trigger involved.
Has anyone had any experience with this? What helped or improved it?

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Is it esophageal spasms?
Ask to check for EGJOO, esophageal junction outflow obstruction.

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I've not heard that it is. Thanks for bringing it up.

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I don’t have a named disorder other than delayed gastric emptying. Nausea is present. Mostly vague but rough like lingering morning sickness. I’m down 35 pounds. I restarted Celexa for anxiety and it did help with my GI distress. My daughter is an NP and mentioned the serotonin connection. The GI nurse prac ordered Gimoti nasal spray. A reformulated Reglan. I already have a facial tic so I don’t use it. She said no episodes of tardive dyskinesia reported but I’m leery.

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Hi, Since you are taking the Buspirone, I'm guessing you had a stomach emptying test to make sure that you don't have Gastroparesis (delayed emptying of the stomach) too. It is uncommon to have both FD and GP but I have heard some people do. I was first diagnosed with Gastroparesis (which I thought was incorrect) and then went to Stanford and diagnosed with funtional dyspepsia (FD) and started on Amitriptyline nightly. My symptoms have subsided. I had all the same symptoms as yours except for the burping. Along with the med, I was advised to see a dietitian to work back certain foods into my diet, a therapist that specializes in CBT and/or digestive issues (FD is very much triggered/caused by stress and a sleep specialist (inadequate sleep can cause certain digestive hormones not to work well and promote stress hormones). If you get 7-9hrs of sleep nightly, you probably don't need to see the sleep specialist. I also had wt loss and was drinking Ensure Plus Complete (3/daily). I was suggest you take a multivitamin if your not already. I know FD is chronic and flare up can occur. There are other meds that are used if the Buspirone isn't doing the job but buspirone is supposed to work very well. Dosage adjustment maybe?? If you need ideas for increasing your calories to promote wt gain, let me know. I would be interested in knowing how long your symptoms were gone or just a little. Also, would like to hear (if you are comfortable) when you had your flare ups, what were your symptoms since you said they changed?

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I forgot to mention that I also take Iberogast which is a mixture of 6 different herbs. I was taking it before I went to Stanford and the GI doc suggested I continue taking it. It can be purchased OTC and I get my from Amazon.

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@anitannapa

Hi, Since you are taking the Buspirone, I'm guessing you had a stomach emptying test to make sure that you don't have Gastroparesis (delayed emptying of the stomach) too. It is uncommon to have both FD and GP but I have heard some people do. I was first diagnosed with Gastroparesis (which I thought was incorrect) and then went to Stanford and diagnosed with funtional dyspepsia (FD) and started on Amitriptyline nightly. My symptoms have subsided. I had all the same symptoms as yours except for the burping. Along with the med, I was advised to see a dietitian to work back certain foods into my diet, a therapist that specializes in CBT and/or digestive issues (FD is very much triggered/caused by stress and a sleep specialist (inadequate sleep can cause certain digestive hormones not to work well and promote stress hormones). If you get 7-9hrs of sleep nightly, you probably don't need to see the sleep specialist. I also had wt loss and was drinking Ensure Plus Complete (3/daily). I was suggest you take a multivitamin if your not already. I know FD is chronic and flare up can occur. There are other meds that are used if the Buspirone isn't doing the job but buspirone is supposed to work very well. Dosage adjustment maybe?? If you need ideas for increasing your calories to promote wt gain, let me know. I would be interested in knowing how long your symptoms were gone or just a little. Also, would like to hear (if you are comfortable) when you had your flare ups, what were your symptoms since you said they changed?

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I wasn't ever advised to see dietitian, therapist, or for sleep, but doing so makes sense. I may want to pursue. My sleep is usually around 6-ish, hasn't been 7-9 for quite a while. Buspirone dosage recently increased. Complicating things: 1 - Have tendency to develop sensitivities/intolerances to certain foods, vitamins, supplements. Can't do Ensure, Boost, etc., because of issues with casein and whey in milk products. (Lactose intolerant too). Tried plant-based Ensure and Orgain. Did fine for several years until became sensitized to them and now have issues with pea protein, which is in so many vegan products. Took multi's for years too, but this year there have been some tolerance issues. I'm now at a point where I can consume plant-based or multi's maybe once every couple weeks. 2 - Have a sensitive stomach - can't take some medications, have to be very careful with others. And yes, please, I would appreciate ideas for increasing calories to promote weight gain. Flare-ups seem to be triggered mostly by chronic stress related to health issues. (The one this year was covid/paxlovid related, body didn't like the paxlovid at all, and promptly sent it up and out). Whenever flares occurred, the symptoms were mostly pretty much the same ones (also include fullness after eating), It's just that you couldn't always predict or count on which ones would show up that week or day or whatever. There have been some times though that I would eat a certain food and feel not too uncomfortable, and try it again some time later and feel much more uncomfortable. Symptoms, when they were pretty much gone, or just a little, ranged anywhere from about 8-9 months to about 15-16 months. Flare times were anywhere from 3 months to about 8-9 months. These are approximate.

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@cindy1952

I wasn't ever advised to see dietitian, therapist, or for sleep, but doing so makes sense. I may want to pursue. My sleep is usually around 6-ish, hasn't been 7-9 for quite a while. Buspirone dosage recently increased. Complicating things: 1 - Have tendency to develop sensitivities/intolerances to certain foods, vitamins, supplements. Can't do Ensure, Boost, etc., because of issues with casein and whey in milk products. (Lactose intolerant too). Tried plant-based Ensure and Orgain. Did fine for several years until became sensitized to them and now have issues with pea protein, which is in so many vegan products. Took multi's for years too, but this year there have been some tolerance issues. I'm now at a point where I can consume plant-based or multi's maybe once every couple weeks. 2 - Have a sensitive stomach - can't take some medications, have to be very careful with others. And yes, please, I would appreciate ideas for increasing calories to promote weight gain. Flare-ups seem to be triggered mostly by chronic stress related to health issues. (The one this year was covid/paxlovid related, body didn't like the paxlovid at all, and promptly sent it up and out). Whenever flares occurred, the symptoms were mostly pretty much the same ones (also include fullness after eating), It's just that you couldn't always predict or count on which ones would show up that week or day or whatever. There have been some times though that I would eat a certain food and feel not too uncomfortable, and try it again some time later and feel much more uncomfortable. Symptoms, when they were pretty much gone, or just a little, ranged anywhere from about 8-9 months to about 15-16 months. Flare times were anywhere from 3 months to about 8-9 months. These are approximate.

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Hi, So I'll try and respond in the order of items you shared, but first I wanted to say your situation is really challenging with your allergies and sensitivities. I really feel for you and can understand why your stress triggers are mostly related to your chronic health issues. Please know I'm just tossing out ideas/suggestions hopefully some may help.
Casein/Whey issues and lactose intolerance - Mayo is high in calories (could choose ones made with avocado or olive oil) and you could have it with tuna, eggs, add it to mashed potatoes (yes, you read it correctly). You will want to look to make sure there is no casein in the mayo. Nuts and nut butters are loaded with calories and you don't need a large amount for the calories to add up. You can ground them up and add to other foods (oatmeal, smoothies (your Orgain drink blended with fruit), soups, noodles, sprinkled on fruit). Nut butters can/can't work for some so you can try different ones (sunflower, almond, cashew). Speaking of nuts, you could try nut milk (coconut milk, almond milk, cashew milk). Hummus is another item high in calories. Avocados are high in calories and can be blended into other foods/soups etc. Several of these items are also good protein sources. beans are good too (added to other foods, blended or whole if you can tolerate. Dried fruits are high in calories and can be eaten on their own or diced/blended and added to other things. Honey can increase calories too. I would suggest trying one new item at a time so if you have issues, you will know what caused it.
You probably already are aware of this, but just in case you don't, ingredients on products are listed in descending orders. You may find items you know cause a problem "sometimes" or always, should be as far down the list. That way the item will have less of them in it and you may be able to tolerate it. Keep in mind, your vitamins and supplements may have casein in them. You may find the liquid version of meds/vitamins are better tolerated and you may need less of them because the liquid versions are better absorbed. Not sure if you saw that I mentioned that I take Iberogast before meals. Not sure if you are willing to try because you are so sensitive, but you could take a small amount before one meal to start. Gradually, add to another meal at small amount, then to your last meal. Then, if needed you could increase amount.
I would definitely suggest meeting with a dietitian and a therapist (especially since you know stress is a trigger). I hope some of this helps. Take care.

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@anitannapa

Hi, So I'll try and respond in the order of items you shared, but first I wanted to say your situation is really challenging with your allergies and sensitivities. I really feel for you and can understand why your stress triggers are mostly related to your chronic health issues. Please know I'm just tossing out ideas/suggestions hopefully some may help.
Casein/Whey issues and lactose intolerance - Mayo is high in calories (could choose ones made with avocado or olive oil) and you could have it with tuna, eggs, add it to mashed potatoes (yes, you read it correctly). You will want to look to make sure there is no casein in the mayo. Nuts and nut butters are loaded with calories and you don't need a large amount for the calories to add up. You can ground them up and add to other foods (oatmeal, smoothies (your Orgain drink blended with fruit), soups, noodles, sprinkled on fruit). Nut butters can/can't work for some so you can try different ones (sunflower, almond, cashew). Speaking of nuts, you could try nut milk (coconut milk, almond milk, cashew milk). Hummus is another item high in calories. Avocados are high in calories and can be blended into other foods/soups etc. Several of these items are also good protein sources. beans are good too (added to other foods, blended or whole if you can tolerate. Dried fruits are high in calories and can be eaten on their own or diced/blended and added to other things. Honey can increase calories too. I would suggest trying one new item at a time so if you have issues, you will know what caused it.
You probably already are aware of this, but just in case you don't, ingredients on products are listed in descending orders. You may find items you know cause a problem "sometimes" or always, should be as far down the list. That way the item will have less of them in it and you may be able to tolerate it. Keep in mind, your vitamins and supplements may have casein in them. You may find the liquid version of meds/vitamins are better tolerated and you may need less of them because the liquid versions are better absorbed. Not sure if you saw that I mentioned that I take Iberogast before meals. Not sure if you are willing to try because you are so sensitive, but you could take a small amount before one meal to start. Gradually, add to another meal at small amount, then to your last meal. Then, if needed you could increase amount.
I would definitely suggest meeting with a dietitian and a therapist (especially since you know stress is a trigger). I hope some of this helps. Take care.

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Thank you so much for all this wonderful information. It is much appreciated.
Also, just wondering how long your symptoms last when you have flare ups.

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@cindy1952

Thank you so much for all this wonderful information. It is much appreciated.
Also, just wondering how long your symptoms last when you have flare ups.

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I was newly diagnosed with FD (2/2025) but like I said, I thought I had it from the beginning (7/2024). Since being seen in 2/25 and I started the med and followed through with the doc's recommendations (see RD and therapist, continue with Iberogast, sleep specialist scheduled just not seen yet), I've yet to have any flare ups. I can still feel full after eating sometimes but it is usually that I may have eaten too much or too fast. Because I haven't had any flare ups, I was interested in how your flare up symptoms were.

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@anitannapa

I was newly diagnosed with FD (2/2025) but like I said, I thought I had it from the beginning (7/2024). Since being seen in 2/25 and I started the med and followed through with the doc's recommendations (see RD and therapist, continue with Iberogast, sleep specialist scheduled just not seen yet), I've yet to have any flare ups. I can still feel full after eating sometimes but it is usually that I may have eaten too much or too fast. Because I haven't had any flare ups, I was interested in how your flare up symptoms were.

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Hi again, just wondering if you ever experienced discomfort or irritation symptoms in your throat. could it be related to the FD and accommodation issues, or maybe something else.

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