Squamocolumnar mucosa with inflammation: How to prevent cancer?
4 years of symptoms - Swollen esophagus with solid food getting stuck.
Distal esophagus biopsy shows Squamocolumnar mucosa with inflammation and reactive changes.
GI doc says it is due to Chronic Active Gastritis with gastrin cell hyperplasia. Extensive atrophy in the gastric antrum and body.
All treatments have failed - PPIs, amoxicillin triple therapy, bismuth quad therapy.
Is there any way to prevent Esophageal Cancer? How long until this develops into cancer?
Interested in more discussions like this? Go to the Esophageal Cancer Support Group.
Connect

@knvdo2, I can understand your concern about the gastrointestinal conditions developing into cancer. It may increase your risk factors, but it doesn't mean you will get cancer. Did your doctor suggest regular monitoring to keep an eye on things?
-
Like -
Helpful -
Hug
1 ReactionNo, the GI doctor didn't really say much about it. He hasn't suggested any other treatments. I don't know what to make of it, so I reached out in this forum hoping someone somewhere knows more about it and can suggest a path forward.
I’m not sure if my case is relevant to yours, but thought I’d post in any case. I have been treated over the past four years for dysplasia of the mucosa of the upper esophagus via cryo- and radio-ablation. Those repeated treatments resulted in a scarring stricture at about 20-25 cm, which was treated over those four years with dilation. That procedure worked for the first three years, but in the fourth, the condition became refractory, and my throat essentially closed up to the extent I could not swallow even water. After the necessity of three more dilations within six weeks, my team (at UCLA) decided the only reasonable option was esophagectomy, even though the dysplasia had not turned into cancer. The esophagectomy surgery took place about ten weeks ago. I won’t lie…it and the initial recovery were difficult. But now, finally I’m feeling more normal and am learning how to eat with my new “plumbing.” My doctors at UCLA were incredibly skillful in performing the long and complex surgery with a completely successful outcome. I posted to let you know that there could be options that you may not be aware of.
-
Like -
Helpful -
Hug
2 Reactions@lindainca thank you for sharing. I wish you continued recovery!