Elevated liver enzymes after gallbladder removal

Posted by bumble81 @bumble81, May 14, 2020

I had my gallbladder out last December. About a month after that my liver enzymes are slightly elevated.

Albumin
Your Value
5.1 GM/DL
Standard Range
3.5 – 5.0 GM/DL

AST
Your Value
45 U/L
Standard Range
14 – 36 U/L

ALT (SGPT)
Your Value
54 U/L
Standard Range
<35 U/L

Is this not unusual after having a gallbladder removed?

Interested in more discussions like this? Go to the Digestive Health group.

Hi @bumble81, There have been formal studies done for patients who have had a laparoscopic cholecystectomy that showed elevated liver enzymes post-op. due to the CO2 pneumoperitoneum (the CO2 air bubble in the abdominal cavity), but it says that the majority of the patients returned to normal levels within a few weeks.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134700/
https://www.ncbi.nlm.nih.gov/pubmed/15776093
https://www.currentsurgery.org/index.php/jcs/article/view/334/314
@rosemarya @hopeful33250 @bonitav and @jimhd have all mentioned having gallbladder surgery, wondering if they have ever heard of this.

Bumble, was your surgery laparoscopic? Have you had your enzymes tested recently and are they still elevated?

REPLY

Hello @bumble81

I can understand your concern over the elevated liver enzymes. We all want to have a healthy liver and if we think there is a problem it can certainly cause anxiety. I had my gallbladder removed a number of years ago, however, it was in connection with another surgery to remove carcinoid cancer from a nearby area in the digestive tract. Because it was part of a larger surgery I was never sure what problems were associated with the gallbladder removal and what was attributed to the more extensive cancer surgery. Here is a Connect discussion from Members who have had gall bladder surgery, https://connect.mayoclinic.org/discussion/gallbladder-surgery/?commentsorderby=DESC&pg=5.

There is another disorder that can follow gallbladder removal. It is rather rare and doctors may not think of it. It is called Sphincter of Oddi dysfunction. According to this information on the NIH website, elevated liver enzymes are typical with SOD. Here is the link with more information, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096116/.

With that in mind, I wonder, as did Amanda (@amandaburnett), which type of gallbladder surgery you had and when you last had the liver enzymes tested.

Please share as you are comfortable doing so, @bumble81, but I'm wondering, besides the elevated liver enzymes, have you had any other symptoms since your surgery? Do you have any other family members with liver and/or gallbladder problems?

REPLY

I had my gallbladder laparoscopically 6 days ago. On Friday night, I began to have this uncontrollable itch all over. I went to the ER the next morning and it was discovered my liver enzymes were significantly elevated (see attached picture). They even reached out to my surgeon who ordered an ultrasound because he did not like my numbers. Preliminary results showed nothing was wrong. They gave me two prescriptions to help with the itching until I follow up with the surgeon on Monday. Based upon my liver enzyme numbers, how concerned should I be?

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@tamekabonner

I had my gallbladder laparoscopically 6 days ago. On Friday night, I began to have this uncontrollable itch all over. I went to the ER the next morning and it was discovered my liver enzymes were significantly elevated (see attached picture). They even reached out to my surgeon who ordered an ultrasound because he did not like my numbers. Preliminary results showed nothing was wrong. They gave me two prescriptions to help with the itching until I follow up with the surgeon on Monday. Based upon my liver enzyme numbers, how concerned should I be?

Jump to this post

Hi @tamekabonner and welcome! You will see I moved your post to a discussion that is talking about the same thing. Mayo Clinic Connect is a platform where patients can connect with other patients to share and compare health issues.
What type of Rxs did they give you and did your surgeon say why the ultrasound was ordered?

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@amandaburnett Thank you! I was given Hydroxyzine & Famotidine.

My surgeon ordered an ultrasound, because he wanted to ensure there wasn't a blockage in the bile ducts. The results were released this morning it stated that the common bile duct was not definitively imaged.

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