Anyone have a problem with losing your big toe nail after chemo?

Posted by jeff1957 @jeff1957, Nov 23, 2023

Since completing chemotherapy I have been having trouble with losing the nails on both my big toes. Is anyone else experiencing this problem?

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Profile picture for happyabby @happyabby

Hello. I have the same problem, just on my right toe. Did the podiatrist say how one might help it along. My toe is so ugly. I wear a colorful bandaid when I wear toe-revealing footwear. Thank you.

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Hi @happyabby Welcome to the ugly toe club. 😁 Chemo did a number on all my nails too. I have photos of how I’d use super glue to hold my fingernails down as they grew out. The gap between old growth was annoying as the nails tended to flip up from the bottom and get caught on everything!
At least in my case, nature finally prevailed and around 18 months or so, most were looking fairly normal. Though my toes always look like God put them on as an afterthought! LOL. The colorful bandaid is a great idea! Own it!

By the way, officially, Welcome to Connect. I’m sorry you’re having to deal with the aftermath of chemo but hope you’re recovering wonderfully and the issue is behind you!!

We have many wonderful cancer support groups in Connect. I’d love to help direct you to a relevant group with members who are sharing a similar diagnosis. If you wouldn’t mind sharing more of your story, what brought you to needing chemotherapy?

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Profile picture for jeff1957 @jeff1957

I looked it up on a podiatrist site they called it chemo toe

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Hello. I have the same problem, just on my right toe. Did the podiatrist say how one might help it along. My toe is so ugly. I wear a colorful bandaid when I wear toe-revealing footwear. Thank you.

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Yes dealing with both big toe nails one worse than other for three years after chemo both clearing up now just trim and keep clean I found,
also have on again off again hiccups , no improvement no matter what I do
Just be thankful for four extra years had lymphoma b cancer and then melanoma, lost half of one ear and minor surgery in four locations
Just had my first great grand daughter this week
At 86 I am just happy to be alive , keep busy or take at least 45 minute walks five days a week or weed my 300 feet of garden with my two grand children
Smile and be happy
Bob allen

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My two big toenails have almost returned to normal about 15 months after they fell off.

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Mine seem to have stop growing. I am about 18 months out after chemotherapy. Still on targeted therapy for nsc
lung cancer.

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Profile picture for dstuyve @dstuyve

I am 10 years out from treatment. Lost both toe nails. Got fungus when they grew back. Could not be treated with oral meds because of being on Tamoxifin. Took Tamoxifen for 10 years. Have now tried laser, oral meds, and just about everything on the market. Fear I will never have regular toenails again.

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I also lost my toenails when I took TAC; taxol, Adriamycin, Cytoxin. They did grow back and get toenail fungus. I have tried the mentholated ointment, and assorted topicals to no avail. I just try to keep them as clean as possible and trimmed as neatly as possible. I keep trying different things and I am always putting something on them. I just hope it keeps them from getting worse.
My doctor advised against me taking orals, due to possible liver damage.
Are your nails painful? Ingrown?

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Profile picture for dstuyve @dstuyve

I am 10 years out from treatment. Lost both toe nails. Got fungus when they grew back. Could not be treated with oral meds because of being on Tamoxifin. Took Tamoxifen for 10 years. Have now tried laser, oral meds, and just about everything on the market. Fear I will never have regular toenails again.

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@dstuyve Welcome to Mayo Clinic Connect. Our cancer journeys often include strange side effects, some we have to live with for a long time.

Have you tried a mentholated ointment, like Vicks VapoRub? My husband uses that for his situation, with success if he is consistent about it.
Ginger

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I am 10 years out from treatment. Lost both toe nails. Got fungus when they grew back. Could not be treated with oral meds because of being on Tamoxifin. Took Tamoxifen for 10 years. Have now tried laser, oral meds, and just about everything on the market. Fear I will never have regular toenails again.

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It’s not over yet mine have came off twice and now growing back for the third time. STRANGE

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I to lost my toenails on my big toes after Chemotherapy. Couldn't figure out why, this explains it. Pretty weird how that happens. Mine are about fully growing back. Thanks for the post. 😀

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