Anyone have a problem with losing your big toe nail after chemo?

I have now joined the chemo toe and fingernail(less) club as well. I received docetaxel as part of my last chemo cocktail for liposarcoma (last infusion was July 8). My hair is growing back nicely but the nails....oof. Almost all fingernails have discoloration, along with both big toenails. The rest of my toenails have thickened. Last night my right big toe nail skittered across the floor when I took off my sandals, I actually didn't feel or see it happen and assumed it was a small rock. Twenty minutes later I caught a glimpse of my toe and was I ever surprised! Today I was putting on socks and my right thumb nail came almost all the way off! The toenail had zero pain, the thumb did. I did not remove it all the way but put Neosporin and a bandaid on it. I'm not sure what to do with it, wait for it to fall all the way off? Sigh. I am ever grateful to my team at Mayo but boy these side effects....
I have to say it was so good finding and reading all these comments and knowing I'm not alone in this journey.

Interesting! I haven't completed chemo, but after 10 months and counting of Gemcitabine + Abraxane + Cisplatin (for pancreatic cancer), I've got 10 healthy fingernails and 8 healthy toenails, but the big toenail on each foot looks horrible. I stubbed my left big toe yesterday, and it started bleeding deep under the nail, and feels like it will come off if I'm not careful.

Which chemo drug(s) were you on?

Seriously the podiatrist had no clue? That's disturbing.
I would think that even having the nails removed to allow them to come in straight could have been offered.

I hope your GP has some ideas for you

I am 3 years post lumpectomy, had chemotherapy, radiation and the right breast lumpectomy. Neuropathy started on both feet shortly thereafter starting chemo, but oncologist kept telling me it would go away, it never has and still problems with walking, numbness and in my fingers on both hands. The nails on both large toes turned dark color and eventually fell off. They started growing back but the tip of the nails on both toes did not grow. I continue to have problems finding shoes because the toes touch the shoes and get very painful and turn bright red from the burning. I put cortisone cream and bandaids over them but only short term solution. Podiatrist has no answer, oncologist refers me to my primary who I am going to see and hope I get some relief. Anyone have any solutions. Thank you.

Hi, my name Julie and my husband is a podiatrist for over 25 years so he has seen everything. I did ask him your question regarding big toe nail. He says toenails and hair are the same thing, keratin. When chemo causes you to lose your hair the same effect happens to your toenails and fingernails. Regarding loose toenails he suggested you have your nail removed, preferably by a podiatrist who knows how to do it properly. We do this procedure many times a week due to ingrown nails or loose nails, and fungal toenails. He numbs the skin around your big toe so you do not feel the injection of numbing medication. He places a tourniquet around base of toe to control bleeding, usually hardly any, and then removes nail. He is able to remove the complete nail. This takes all of a few seconds. If you try to hold nail on with bandaid it will usually get caught on something and rip off. When this happens some of the nail bed might be left and cause pain and infection. Also when nail grows without be completely removed it will cause pain, usually infection and more trouble than it’s worth. Especially if you have diabetes of poor circulation. Almost all insurance plans pay for this procedure. At our office for those who do not have insurance we have always worked something out. Doc says it takes about 6 months to completely grow out. ( this is the time for the colored bandaid!) same with fingernails only less time to grow out depending on health status. The toe is sore for few days. Everyone is able to wear shoes, sandals might be more comfortable but we have many people who go back to work next day in steel toe boots. The healing process takes longer and more painful if you let toe get infected, or torn off. NO lose nail will ever grow out normally by being left alone. The blood supply has been compromised so better and cheaper to take care of it sooner than later. I have had toenails removed due to fungus, it is truly not that bad. (Thinking about it is worse than getting it done) Everyone remember, just the same as your hair falling out and growing back, toenails work same way. We all have that period of “strange things that happen after chemo and radiation “ things will get better! If you have any other questions, please don’t hesitate to message me. I have a very good source of information sitting on my couch!
Take Care… Julie Hart

I lost my baby toenail. Just came right off. Poof!

I am 3 years post lumpectomy, had chemotherapy, radiation and the right breast lumpectomy. Neuropathy started on both feet shortly thereafter starting chemo, but oncologist kept telling me it would go away, it never has and still problems with walking, numbness and in my fingers on both hands. The nails on both large toes turned dark color and eventually fell off. They started growing back but the tip of the nails on both toes did not grow. I continue to have problems finding shoes because the toes touch the shoes and get very painful and turn bright red from the burning. I put cortisone cream and bandaids over them but only short term solution. Podiatrist has no answer, oncologist refers me to my primary who I am going to see and hope I get some relief. Anyone have any solutions. Thank you.