Statin discontinued due to neuropathy. What are some alternatives?

Posted by Nazir Khan @nukhan, Jan 19, 2020

I have been using Lipitor since 2007 for lowering my cholesterol which is on the list of those medicines that are suspected to cause neuropathy. I am thinking of discontinuing this menace but before doing so want to check with those members who have discontinued using statin and what is their experience. What alternative methods have they since adopted for lowering their cholesterol .. diet, alternative medication, exercise or anything else ?

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Profile picture for ebero @ebero

I am managing high cholesterol with diet. I was never able to tolerate statins, and I have PN. I avoid red meat, dairy and sugar. Plus I use olive oil in my cooking and salads. Good luck to you!

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I wish! I eat no meat (just fish), no dairy and practically the only sugar
I get is in a bit of dark chocolate after dinner. For years I have only
used olive oil (very little, at that) and I take an Omega 3 supplement. I
have aerobics, strength training and stretching classes three times a week.
I am 5' 4" and weigh 128 lbs. Still, my cholesterol was at 336!
I always avoided statins because my Cardiac Calcium Score came back
as Zero! No blockage of any arteries. But, last year my CAC (Coronary
Artery Calcium) score crept up to 20% and while that is not bad, I'm not
comfortable with the somewhat sudden increase. So, here I am,
experimenting with the lowest dose of statin that might keep the
cholesterol levels in check, but not exacerbate the peripheral neuropathy.
While diet and lifestyle are the answer for some, it is not
necessarily going to work for everyone.

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I am managing high cholesterol with diet. I was never able to tolerate statins, and I have PN. I avoid red meat, dairy and sugar. Plus I use olive oil in my cooking and salads. Good luck to you!

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I cannot take statins or Zetia, so I am taking Nexletol with Repatha. I had some side effects from Repatha, but they went away after a month. You need to take a statin with Repatha to work well, so my cardiologist added Nexletol. It works different from statins - a different process. I have not had any side effects from Nexletol, and I have been on both meds for over 3 years.

Just a warning, my insurance doesn’t like paying for both meds. But my lipidologist put extra effort in and got it approved. There are no generics for Repatha or Nexletol, so they are expensive. Repatha is doing most of the work because Nexletol doesn’t lower cholesterol as much as statins, but every little bit helps.

All the best to you. 😊

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Profile picture for MamaMarch @mamamarch

After years of being told to take them, I finally gave in when my Total Cholesterol levels reached 330. This is clearly a familial problem as I have a very heathly lifestyle but a family history of cardiovascular issues.
They said they'd start me on a low dose; Rosuvastatin (Crestor) 20 mg! After only a few days, I called and said I'm cutting them in half! Was still able to get my levels down to 170 in no time, but still having leg pain.
Just curious to see if those levels would hold on their own, so I stopped the statin completely for several months. Levels went back up! I agreed to go back on at 5mg! Leg pain is greatly reduced, but not gone. I have blood work tomorrow to see what my levels are. If they are reasonable (not necessarily low!) I think I can live with this dosage.
If my levels drop down to 170 again, I swear, I'm going to cut these tiny little 5 mg. tablets in half, LOL!

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Some people take every other day

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Profile picture for charliesophiedaisyro @charliesophiedaisyro

Please let me know how this works. I know my GP will push statins on me next time I see him. I swear I will not go back to Statins because of the horrible leg cramps.

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After years of being told to take them, I finally gave in when my Total Cholesterol levels reached 330. This is clearly a familial problem as I have a very heathly lifestyle but a family history of cardiovascular issues.
They said they'd start me on a low dose; Rosuvastatin (Crestor) 20 mg! After only a few days, I called and said I'm cutting them in half! Was still able to get my levels down to 170 in no time, but still having leg pain.
Just curious to see if those levels would hold on their own, so I stopped the statin completely for several months. Levels went back up! I agreed to go back on at 5mg! Leg pain is greatly reduced, but not gone. I have blood work tomorrow to see what my levels are. If they are reasonable (not necessarily low!) I think I can live with this dosage.
If my levels drop down to 170 again, I swear, I'm going to cut these tiny little 5 mg. tablets in half, LOL!

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Profile picture for mdamiani57 @mdamiani57

Oh sorry it was Atorvastatin I'm going to start a different one tomorrow starts with Pr something I think it's Pravastatin or Provastatin

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Please let me know how this works. I know my GP will push statins on me next time I see him. I swear I will not go back to Statins because of the horrible leg cramps.

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Profile picture for charliesophiedaisyro @charliesophiedaisyro

What statin was discontinued ?I have horrible leg cramps with statins. What about Repatha?

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Oh sorry it was Atorvastatin I'm going to start a different one tomorrow starts with Pr something I think it's Pravastatin or Provastatin

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Profile picture for mdamiani57 @mdamiani57

2 or 3 days but still have a little but he wants me to try another statin with less side effects.

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What statin was discontinued ?I have horrible leg cramps with statins. What about Repatha?

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Profile picture for celia16 @celia16

How long after you stopped med did symptoms leave?

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2 or 3 days but still have a little but he wants me to try another statin with less side effects.

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Profile picture for celia16 @celia16

I understand those tests and results. My total cholesterol was around 150 last time, but where do get the number 9.8, that you describe above?

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Hi,
Different measurements are used around the world. IE a US gallon is only 5/6ths of a "real gallon"! It was like learning a different language when I lived in USA. When in Rome, I guess. No doubt there is a conversion chart somewhere out there.
Cheers

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