Chemotherapy-induced neuropathy: What helps get rid of it?

Posted by taxlady @taxlady, Jan 31, 2023

I finished chemo April of 2022
I have neuropathy in my fingers and feet. It doesn’t seem to be going away. What are treatments I can do to help get rid of it.

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@erichendrix

Prescribed Pregabalin, Duloxetine, Nortriptyline, Naloxone, Gabapentin, and Buprenorphine for neuropathy, none of which helped at all. Very bad adverse reaction to Naloxone, the horrible “side” (think “direct”) effects of which I struggle to describe. I was on my knees praying to God that it would wear off. A few days ago was prescribed Buprenorphine which, to my great shock and dismay, was, conservatively, three times as bad as Naloxone and forced me to go to the ER, where they did nothing helpful, however they did succeed in performing a useless chest x-ray, CT scan, and blood test, all clear as I knew they would be. An overnight hospital stay, then back home with the recommendation from my GP that I contact the Mayo Clinic where I might benefit from a team of experts looking at my case. Not sure why my medical team here is not a "team"? Communication breakdowns everywhere.

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I too tried duloxetine. Couldn’t sleep, very tired, and nauseous all the time and then I was supposed to take 2 pills. I never made it and just quit. I have more pain now in my fingertips that hinders a lot of opening and closing things. Very heat and cold sensitive. Help?

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@jodimj

I’m only two treatments out of 6 scheduled in, and the pain is off the charts. It’s interrupting my sleep, no its stopping sleep!! Walking has always been a vice, my drug of choice, so now there’s some depression sneaking in without the walks as well! Not sure what all I’m investing in here for a future today. Great full for input here, not always taking the best notes though.

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Please talk to your doctor about this and if that doctor doesn’t take you seriously talk to your primary care doctor or ask for a referral to a neurologist. This is a serious thing and as you are losing your “drug of choice” it is maybe more serious for you.
If you aren’t getting the rest you need during chemo, that is not really helpful either.
May I ask what you are taking chemo for and what drugs you are receiving?

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I’m only two treatments out of 6 scheduled in, and the pain is off the charts. It’s interrupting my sleep, no its stopping sleep!! Walking has always been a vice, my drug of choice, so now there’s some depression sneaking in without the walks as well! Not sure what all I’m investing in here for a future today. Great full for input here, not always taking the best notes though.

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@marciak9

I’m so sorry to hear about your condition. It sounds unbearable. My PN is just my feet and finger tips. It’s not painful but makes me crazy with the pins and needles. Every Dr I have asked has told me they don’t know how to fix it. Until they do, I’ll focus on the good things in my life.

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It is unbearable and a Vaccine did it to me. I didn't any of that until I took that Vaccine and I'll never take another one again. I always took vaccines until 2019 when that happened to me. No more, no flu shots, no nothing. I don't trust them.

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An 83 year ld friend of mine with peripheralneuropathy and shoulder pain started using CBD drops recently and his pain is much improved.

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@dablues

I was diagnosed in 2019 with peripheral neuropathy and in 2023 it is now polyneuropathy demyelinating and so far no one has referred me to a doctor for treatment and the pain is just been getting worse since 2019 and I tried all kinds of things to fix myself since the neurologist only prescribed cream which did nothing. I'm very upset that I can't get help and have to live with this pain especially at night.

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I’m so sorry to hear about your condition. It sounds unbearable. My PN is just my feet and finger tips. It’s not painful but makes me crazy with the pins and needles. Every Dr I have asked has told me they don’t know how to fix it. Until they do, I’ll focus on the good things in my life.

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@marciak9

I finished chemo last May and the neuropathy my mouth has resolved, but I still have it in my fingers and feet. The doctors I talk to say there is no cure. It should resolve on its own but can take a long time. Nerves grow back very slowly.

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I was diagnosed in 2019 with peripheral neuropathy and in 2023 it is now polyneuropathy demyelinating and so far no one has referred me to a doctor for treatment and the pain is just been getting worse since 2019 and I tried all kinds of things to fix myself since the neurologist only prescribed cream which did nothing. I'm very upset that I can't get help and have to live with this pain especially at night.

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Thank you for the link. The information was intriguing. Still, the words could and potential. The study was not done on humans. The clinical trial I mentioned involves a lot of monitoring with blood work, skin biopsies, and ultrasounds keeping a close eye on the possibility of cancer reoccurring. Participants are screened carefully, and must be cancer free. Again, I'm not advocating for or against. I don't regret participating in the trial, and would do it again.

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@dlmdinia

Do you have the link to this study? I note the word "may" increase the risk rather than "does". That implies conjecture rather than statistics.

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This one only one of many things published about the risk of cancer with NR. If you do a google search for nicotinamide riboside and cancer risks you will find them.
This is one of the ones I read. (I didn’t save the link)
https://showme.missouri.edu/2022/insight-to-popular-supplements-potential-role-in-cancer-progression/

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Do you have the link to this study? I note the word "may" increase the risk rather than "does". That implies conjecture rather than statistics.

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