Can I cut Glaxambi by half?

Posted by jfching @jfching, Nov 5, 2023

Hello, I had high HB1AC reading of 14 last year August when I was diagnosed with heart failure. My cardio was concentrated on the heart and took good care of it. He made me go om 16 hr fasting and I lost 20+ lbs since then due to fasting, exercise and being conscious of food intake. I was prescribed Glyxambi last May..Now my hb1ac is 6.1 and I strictly adhere to fasting last Sept.Can I cut the pill in half since I feel dehydrated due to this drug. Thank you

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Scott R L | @scottrl | Nov 5, 2023

I don't know anything about the drug, but I commend you on getting your A1c down so dramatically! Keep up the good work.

Cheryl, Volunteer Mentor | @cehunt57 | Nov 5, 2023

@jfching welcome to Mayo Clinic Connect. I too want to commend you on the improvement in HgA1C and on the weight loss. I also am unfamiliar with the drug Glaxambi. I would be hesitant to alter the dose. Could you discuss the dose with the prescribing provider? If it is causing dehydration perhaps your provider can consider alternate medications?

nursetaytay | @nursetaytay | Nov 11, 2023

Hi! Not sure if you have found an answer for this question YET, but I would suggest speaking with your pharmacist about this, or your prescribing doc!

I looked in 2 of my drug books and did a whole bunch of online searching and couldn’t find ANYTHING! Except “the manufacturer of Glyxambi does not specify if it can be cut or crushed” which doesn’t answer anything!

Sorry I couldn’t be of more help! Soooo.. asking pharmacist (or doc!) is your best bet!