Can anyone speak to the pros/cons of arimidex vs. tamoxifen?

Posted by lecase @lecase, May 6, 2012

Can anyone speak to the pros/cons of arimidex vs. tomoxifen…..I’ve been on tomoxifen for 4 months post lumpectomy, chemo and radiation. Hormone levels now test out in menopause range so provider wants to switch me to arimidex. I’m reading conflicting information…..can anyone help?

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Good question as I’ve read conflicting info too. I was on tamoxifen until they discovered I wasn’t able to process it due to a genetic mutation. So I was switched to Arimidex and personally I prefer the tamoxifen! I had no side effects with it other than some slight changes in my hair. The Arimidex causes a lot of joint pain and stiffness in my hips and lower back, knees and left thumb. I know it’s the Arimidex because I stopped taking it for a week over summer vacation and felt immensely better within 24 hours .

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Weill my AL treatments be as effective if I am taking Prozac. I have read that tomoxifen is not effective when taking SSRI but AL work differently

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I took tomoxifen for 4 and a half years and I am 11 years cancer free. I did have some side effects.

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@abartels– Congratulations! That is great news!

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Try some gentle yoga. A ‘restore’ class might help, or at least give you some temporary relief. Do some walking outdoors when the weather permits. I’m 65 and also have arthritis in my shoulders and knees. I know it’s hard to move when your joints ache, but keeping myself moving seems to help me. I have a treadmill for the days that the weather doesn’t permit being outside.

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If you live in the Rochester Area… there is a restorative yoga class which is free for breast cancer survivors.
https://www.climbroca.com/phoenix-yoga-program/
It is wonderful 🙂

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@abartels

I took tomoxifen for 4 and a half years and I am 11 years cancer free. I did have some side effects.

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@abartels, what were your negative side effects to Tamoxifen? I've been on it for 5 1/2 months and I have also had some negative effects.

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I was on tamoxifen 5 years worst thing were hot flashes, and I was also going through menopause so prob would have had them anyway… annoying but I got through… not horrible … again annoying! I am now on arimidex for 4 years… one year to go… bc I needed the extra time! I have some stiffness here and there, is it def from meds… idk for sure… I will be 60 next month so could be just normal. That’s all for me! Nothing horrible.
Everyone is different! It does save lives♥️ So be your own judge. I am 10 years a survivor in October and I have to believe these meds are part of the reason. Almost afraid to go off… but it will be time😏

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@lisajoann

I was on tamoxifen 5 years worst thing were hot flashes, and I was also going through menopause so prob would have had them anyway… annoying but I got through… not horrible … again annoying! I am now on arimidex for 4 years… one year to go… bc I needed the extra time! I have some stiffness here and there, is it def from meds… idk for sure… I will be 60 next month so could be just normal. That’s all for me! Nothing horrible.
Everyone is different! It does save lives♥️ So be your own judge. I am 10 years a survivor in October and I have to believe these meds are part of the reason. Almost afraid to go off… but it will be time😏

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It's great to read the words 'ten years' and 'survivor' in the same sentence. Kudos to you and medical science.

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Thank you and I pray for all who are fighting this battle💞

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