1. < Prostate Cancer

Can anyone share their experience with Pluvicto?

Posted by vcash @vcash, Apr 22, 2024

My 85 year old dad has prostate cancer that has metastasized to his bones. Zytiga is no longer effective. He is considering Pluvicto. I would appreciate input from those who have used Pluvicto.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

sillyoyster | @sillyoyster | Feb 1 12:30pm
In reply to @jeffmarc "Many people who have had that radiation are also getting Pluvicto. It is an infusion so..." + (show)
@jeffmarc

Many people who have had that radiation are also getting Pluvicto. It is an infusion so there is no problem, it’s not radiation.

Jump to this post

Thanks Jeff. Do you know if Pluvicto can be delivered through a butterfly needle? My veins shrank due to the chemo.

REPLY
1 reply
jeffMar | @jeffmarc | Feb 1 11:09am
In reply to @sillyoyster "I had radiation to my prostate bed two years after surgery. It gave me my lifetime..." + (show)
@sillyoyster

I had radiation to my prostate bed two years after surgery. It gave me my lifetime total radiation exposure. Won't pluvicto add to this amount? Would pluvicto be safe for me?

Jump to this post

Many people who have had that radiation are also getting Pluvicto. It is an infusion so there is no problem, it’s not radiation.

REPLY
1 reply
sillyoyster | @sillyoyster | Feb 1 10:34am
In reply to @colleenyoung "@vcash, you may also be interested in these related discussions: - Anyone on Pluvicto? Looking for..." + (show)
@colleenyoung

@vcash, you may also be interested in these related discussions:
- Anyone on Pluvicto? Looking for a support team
https://connect.mayoclinic.org/discussion/anyone-on-pluvicto/
- Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?
https://connect.mayoclinic.org/discussion/any-one-on-pluvecto-a-relatively-new-drug/
See all Pluvicto discussions here https://connect.mayoclinic.org/group/prostate-cancer/?search=Pluvicto&index=discussions

Jump to this post

I had radiation to my prostate bed two years after surgery. It gave me my lifetime total radiation exposure. Won't pluvicto add to this amount? Would pluvicto be safe for me?

REPLY
1 reply
ljbeeson | @ljbeeson | Jan 31 12:42pm
In reply to @redroadtraveler "I am the poster boy for the Pluvicto treatment, having gone through all six treatments with..." + (show)
@redroadtraveler

I am the poster boy for the Pluvicto treatment, having gone through all six treatments with minimal side effects and maximum benefits.

In my opinion the hazmat suit is overkill. I DO however highly recommend you get a dosimeter (about $100 from Amazon) and daily monitor your readings at RMS length and t skin level. We are an hour and a half drive home after the treatment and felt it worked ok to just sit the patient as fr away from the driver as possible for the drive home.

Although for me the Pluvicto treatment I would count as a success, at this point I have lost the battle. I am on hospice care on my last legs awaiting my final journey.
Unfortunately there is no cure. Every treatment, no matter how good, is simply a delay. In my case I was able to delay about five years and maximize my quality of life during that time.

Jump to this post

Sending hugs back and much gratitude for sharing your experience. This forum is wonderful and so are you.

REPLY
redroadtraveler | @redroadtraveler | Jan 24 6:42pm

Driver front left.

Passenger back right covered with blankets..

You only have a three mile ride. I had an hour and a half ride with no problem.

More important is taking your daily dosimeter readings and maintaining your distance accordingly.

REPLY
ljbeeson | @ljbeeson | Jan 23 3:03pm
In reply to @redroadtraveler "For those following my Pluvicto treatment, my personal protocol and why, I am now two weeks..." + (show)
@redroadtraveler

For those following my Pluvicto treatment, my personal protocol and why, I am now two weeks after my fourth Pluvicto radiation infusion.

My current radiation readings are:

Arms length (3 feet): 0.01

One foot away: 0.03

Next to body: 0.22

If you recall, they turn you loose from the hospital when your 3 foot reading is around 3.

So my personal experience as above shows a decline in my 3 foot measurement from a 3 to a negligible 0.01.

With my next to body reading having declined to 0.22 I now deem myself to be relatively safe to be with people and to have extended contact.

My concern on all of this is to NOT cause "collateral radiation damage" to any caregivers, friends and loved ones. The cumulative level of damage through exposure is the strength of the radiation times the amount of time exposed. At my current next to body reading of 0.22 millirems per hour a person who was in constant contact with me for one hour would receive only 0.22 millirems of radiation. This may be compared to the standard cumulative radiation limit level of 100 millirems per year.

To summarize, my personal protocol is to isolate myself completely for one week, to allow casual, but no extended contact for the second week after treatment, and to resume "normal" life thereafter until my next treatment which comes in four more weeks if thete are no complicating factors.

Hope this information has been useful to those who are interested in a deeper dive into the effect of Pluvicto treatments on their body as it relates to radiation exposure to caregivers, friends and family.

Jump to this post

Hi, This is many months after your treatment which my husband will start at UCSF ASAP. Your information is very very helpful and one question is riding in a car so close to each other at 3 when treatment ends and we drive home for 3 miles. How did you learn about measuring the radiation so well. I will buy a geiger counter too. I appreciate your help and love this forum and welcome your further updates. ljbeeson

REPLY
redroadtraveler | @redroadtraveler | Jan 23 12:57pm

I'm 81 years old. Have been through all the FDA approved protocols except chemotherapy. It was my choice to not undergo chemotherapy. Everything does it's part in delaying the inevitable.

REPLY
1 reply
melcanada | @melcanada | Jan 23 7:04am
In reply to @redroadtraveler "I am the poster boy for the Pluvicto treatment, having gone through all six treatments with..." + (show)
@redroadtraveler

I am the poster boy for the Pluvicto treatment, having gone through all six treatments with minimal side effects and maximum benefits.

In my opinion the hazmat suit is overkill. I DO however highly recommend you get a dosimeter (about $100 from Amazon) and daily monitor your readings at RMS length and t skin level. We are an hour and a half drive home after the treatment and felt it worked ok to just sit the patient as fr away from the driver as possible for the drive home.

Although for me the Pluvicto treatment I would count as a success, at this point I have lost the battle. I am on hospice care on my last legs awaiting my final journey.
Unfortunately there is no cure. Every treatment, no matter how good, is simply a delay. In my case I was able to delay about five years and maximize my quality of life during that time.

Jump to this post

How old are you

Did you do xtandi and Zytega and Radium 223 before LU 177

REPLY
redroadtraveler | @redroadtraveler | Jan 22 8:23pm
In reply to @ljbeeson "I cannot express my respect and gratitude for your information. My husband was just told he..." + (show)
@ljbeeson

I cannot express my respect and gratitude for your information. My husband was just told he must start that at UCSF as soon as it gets set up. I have lots of questions and one of the first ones is how about transporting my husband home in the car after treatments. Is a hazmat suit crazy I see they sell on Amazon. I hope to stay in touch with you and I send you love, light and healing in your journey. The doctor really didn't go over any choices or side effects and told us how lucky my hubby was that this treatment is available now. It is so important to know how to minimize suffering and side effects and protect one's family and friends. Thanks 'Lynne

Jump to this post

I am the poster boy for the Pluvicto treatment, having gone through all six treatments with minimal side effects and maximum benefits.

In my opinion the hazmat suit is overkill. I DO however highly recommend you get a dosimeter (about $100 from Amazon) and daily monitor your readings at RMS length and t skin level. We are an hour and a half drive home after the treatment and felt it worked ok to just sit the patient as fr away from the driver as possible for the drive home.

Although for me the Pluvicto treatment I would count as a success, at this point I have lost the battle. I am on hospice care on my last legs awaiting my final journey.
Unfortunately there is no cure. Every treatment, no matter how good, is simply a delay. In my case I was able to delay about five years and maximize my quality of life during that time.

REPLY
3 replies
jeffMar | @jeffmarc | Jan 22 6:43pm
In reply to @ljbeeson "I cannot express my respect and gratitude for your information. My husband was just told he..." + (show)
@ljbeeson

I cannot express my respect and gratitude for your information. My husband was just told he must start that at UCSF as soon as it gets set up. I have lots of questions and one of the first ones is how about transporting my husband home in the car after treatments. Is a hazmat suit crazy I see they sell on Amazon. I hope to stay in touch with you and I send you love, light and healing in your journey. The doctor really didn't go over any choices or side effects and told us how lucky my hubby was that this treatment is available now. It is so important to know how to minimize suffering and side effects and protect one's family and friends. Thanks 'Lynne

Jump to this post

How long is the drive home? Back seat may do. 3’ apart is pretty safe.

REPLY
View MoreView Less
Please sign in or register to post a reply.