Can anyone share their experience with Pluvicto?

Russ just got home from his 2 nd pluvicto injection from the mayo today ! They told us no worries u can drive him home ! Sleep in the same bed ! Just no kissing for 3 days ! 😊

Just got back home from my Pluvicto treatment number 5. I drove myself as I am generally tolerating these infusions reasonably well with my primary side effects being constipation and general tiredness for a week or two.

Today they had to poke me three times before they got the needle installed properly. Ugh. I'm not real good with needles. I'd make a bad drug addict. LOL.

Anyway, I made it home ok after the hour and a half drive, but now I'm weak, worn out, and crashed on the bed in my bedroom where I will basically isolate myself for one week with no contact. The official guidelines are to stay a minimum of three feet away from everyone for three days, but my personal opinion is I should just completely isolate myself for a week as long as I am able to function without help - i.e. have the ability to feed myself and take care of my bathroom needs without assistance. I tend to be extra cautious about exposing anyone else to my radiation.

To Add to my previous reply to the question about the radiation exposure to the person driving a friend sitting diagonally in the back seat - as I said, you likely are getting about three millirems of radiation each hour, so during a two hour drive you would be getting a out six millirems of exposure. My conclusion that that is something I would not be concerned about is based on the official radiation guidelines which say a person should limit their annual exposure to no more than 100 millirems. So in one drive you would be getting about six percent or so of your annual limit. In my world this would be totally acceptable in order to do this for a friend.

I also agree with the other person's observation about the reality of transportation in Manhattan. The doctors give their theoretical guidelines to stay three feet away from people for three days (not enough in my opinion) but they can do nothing about the reality of any patient who is forced to rely on public transportation.

I am due for my fifth infusion tomorrow. Stay tuned for further developments.

Thank you for your response .
I know him since we were teenagers and want to do all I can to help .
Besides his concern whether he'd been able to drive home himself , I think what you said also applied - he wanted someone there with him to feel more comfortable .

@waldipup, I'm sorry that your good deed for your friend is causing you concern.

With you and your friend being separated between the front seat and him diagonally behind you in the back seat, your distance will met or exceeded the required 3 feet and your time together was limited to 2 hours. The recommendation is to LIMIT close contact (less than 1 meter or 3 feet).

This is the same recommendation for men and women. However, extra precautions are suggested for pregnant women and children.

Thank you for your kindness and offering to drive your friend. I'm sure it was a great comfort to him to not have to drive himself. This is a time when he needs friends like you.

I don't put much faith in what the radiation doctors have to say about the radiation issues .
They released him with no warnings regarding a possible cab driver (or in my case , friend driver) , and being in Manhattan , he very likely could have taken a bus or train at rush hour pressed against others for periods of time .

So they're not too focused on that issue . And I don't think they know for sure just where "dangerous" ends and "ok" begins anyway , it's kinda an uncertainty .

Hi and thanks . My friend told me 3 feet , but no women . It hit me that if "no women" , then it can penetrate , and penetrate a man just as easily , and then I realized I shouldn't have done it .
But you say 6 for two hours at 3 ft. enclosed is not too bad?

He'd heard there may be debilitating side effects so he was uncomfortable to drive into Manhattan NY and possibly be stuck if unable to drive home .
But so far two treatments with no side effects .
Unfortunately , just before his third treatment his Hemoglobin dropped to the 7's requiring a blood transfusion and now he is experiencing severe lower back pain related to the PC so his third treatment is on hold .
Thanks again .

First of all, the usual "medical disclaimer". I am not a doctor. This is a question you should pose to the radiation doctor.

Having said that, I can tell you my personal experience.

With you driving and him sitting diagonally in the back seat you are about three feet away from each other. They turn you loose from the Pluvicto administration when your radiation level is around three. Radiation exposure is cumulative so during the two hour drive you are getting about a six - not great but in my opinion nothing to be particularly concerned about.

I live about an hour and a half drive from my treatment center. I too have minimal side effects from the treatment. As such. I drive myself to and from the treatment in order to minimize me exposing anyone else.

After treatment. I completely isolate myself for one week based on my declining radiation levels. They tell you to isolate at least three feet for three days, but I am personally not comfortable that that is sufficient for my tastes. I then restrict my close contact for a second week (no sleeping together, brief hugs or handshakes ok but no prolonged physical contact etc.) After those two weeks my radiation level is negligible so all contact is fair game.

Since your friend also has minimal side effects, is there any reason he couldn't drive himself?

Hi redro . First off wishing you the best results , my friend so far had 2 P treatments , feels great and no side effects .
My concern is that I'd picked him up immediately following his first treatment and it was a 2 hour ride to get him home with the car windows closed and he in the back seat diagonally behind me .
I see that you are well versed in exposure issues and wonder if you feel that I may have been affected by my immediate , enclosed , proximate 2 hour contact?

I am tolerating the treatment fairly well. At this point in the history of allopathic medicine this Pluvicto treatment is the last arrow in their quiver, so it was my ONLY choice in allopathic medicine. (I declined chemotherapy because it made no sense to me to kill off everything and hope that the good comes back faster than the bad.)

They won't do the real in depth scans until the six treatments are completed. I am receiving treatment number 5 next week, so it will be another 2-3 months before I can get a real reading on my then current condition after having gone through all six Pluvicto treatments. I am doing well with the treatments, however, so I have hopes that they have at least been somewhat effective.

I am also doing non-allopathic approved protocols.