Can anyone share their experience with Pluvicto?

Posted by vcash @vcash, Apr 22, 2024

My 85 year old dad has prostate cancer that has metastasized to his bones. Zytiga is no longer effective. He is considering Pluvicto. I would appreciate input from those who have used Pluvicto.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Profile picture for djnavigator25 @djnavigator25

I am starting Pluvicto soon. I chuckled about the Nuke subs. That was my experience, too, about 50 years ago. All the best!

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What is your experience so far ?

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Profile picture for jay0013 @jay0013

Has anyone finished all 6 treatments with Pluvicto? If so would you please share the outcome. How long has it been since completing the treatment?
Thank you for your reply
Jay

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I know a few people that have completed it and results vary. Some had the cancer stay away for a well over a year Other people have had it come back.

It is a known fact that 1/3 of the people get really good results 1/3 of the people get OK results and 1/3 of the people get no results at all.

One thing you should be aware of are Pluvicto genetic issues
RB1, PTen, TP53 are Pluvicto resistant
ATM & BRCA work better with Pluvicto

If you got a hereditary, genetic test You would know if you have any of these. Has it been offered to you by a doctor? You can get it done free with the below link, if you live in the United States. Do not check the box that you want your doctor involved or they won’t send you the kit until they get in contact with your doctor. It takes about three weeks to get the results and then a genetic counselor will call you.
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Prostatecancerpromise.org

You get a somatic Genetic test using blood or tissue to find out whether or not you have one of those genetic issues now. Things do change, and some people do get these genetic anomalies. Ask your doctor about this.

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Has anyone finished all 6 treatments with Pluvicto? If so would you please share the outcome. How long has it been since completing the treatment?
Thank you for your reply
Jay

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Profile picture for mary1915 @mary1915

Thank you for the encouragement. I pray it works for my husband.

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Thought and prayers🙏

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Profile picture for kjacko @kjacko

My friend just ended his Pluvicto treatments and said it’s the best he’s felt in four years. Hope this helps and good luck.

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Thank you for the encouragement. I pray it works for my husband.

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Profile picture for mary1915 @mary1915

Thank for sharing.
My husband(75 years old) just started his 1st treatment of Pluvicto. He has lots of pain in his lower back and some leg pains. Has issues walking. His next 2nd treatment is in August. What should he expect on the 2nd round?

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Usually, the side effects are similar for the first three treatments. Some people can’t get past the first visit without serious side effects.

He will probably feel Back to normal a Couple of weeks before his August treatment

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My friend just ended his Pluvicto treatments and said it’s the best he’s felt in four years. Hope this helps and good luck.

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Profile picture for eugenelapietra1 @eugenelapietra1

76 years old in the same boat your dads in. Treatment #1 not bad at all, treatment #2 a little rough, Treatment #3 a total nightmare, Treatment #5 I didn't think I was going to survive. I don"t have a choice I'll take Treatment #5 and pray..........The rub is , everyone may have a different experience so I suggest gathering more testimonials . Pluvicto with all its unknowns is still the only game in town. If you decide to go through with the treatments you can contact me and I'll share with you some tips on how to make your dads trip easier. God Bless ,Gene

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Thank for sharing.
My husband(75 years old) just started his 1st treatment of Pluvicto. He has lots of pain in his lower back and some leg pains. Has issues walking. His next 2nd treatment is in August. What should he expect on the 2nd round?

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Trip out, lunch with a good friend, all went well, still a bit of dizziness, fatigue seems to be more manageable.
Ain't this FUN?

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Day 8? Can't even think anymore.
The pain has stabilized out to almost "undetectable".
However, last 2-3 days the fatigue has been EXTREME!.
Sleep almost all day, and all night.
When I do arise, VERY dizzy and wobbly.
Can't make it round trip to mailbox.
Used an old trick told me by my GP almost 40 years ago, gargle and swish with Hydrogen Peroxide. Two days, twice a day, took most of the coating off my tongue, and I have a lot of my taste back.

Gonna try going out today. No Oxycodone (test to see if that is in issue with fatigue) but 100mg Provigil, which did (surprisingly) NOTHING Sunday morning.

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