Can anyone share their experience with Pluvicto?

So you’re taking 5 mg, I think it’s a smallest they make, The selection goes to 100 (or more?). That might relieve someone of consciousness.

I have a few of those 5’s leftover from having my knee replaced. They come in handy when you strain a muscle in the back in the gym and can’t move without pain. I find I have to be really careful in the gym, At 77 I can’t even increase the weights I am using by 10 pounds after three or four months without pulling something. The 5’s were worthless when I had my knee replaced.

Have to go look. Smaller than the Saccharin tablets we used to steal from Grandpa!

This is copied from my on-line med list:
"Take 0.5 tablets (2.5 mg) by mouth every 6 hours as needed for severe pain."
Try to cut one, you end up with powder, so I take a whole one.
Never done three in a day before.
Probably get away with two if I wash them down with Bourbon!
(I can say that because I HATE Bourbon!) Gets the Dr's attention anyway.

How many milligrams of oxy do you need to take?

Day 4 ends now. 95 hours since infusion. Yesterday evening.....not bad at all. Can we hope?
Slept very well. 2 Aleve early, one Oxycodone before bed. Got up this morning........no pain.
We decided to keep Oxy on board all day, so one when I got up, I'll do one around 2 or 3 PM, last one before bed.
Tired and feel weak, addressed with 100mg Provigil this morning.
The clinic likes the scan results. Baseline. Next 2 scans will tell them.

Semi-worked for me, just not in the way I hoped it would. I am a four Plavicto shot survivor. 4.6 Years since my advanced prostate cancer diagnosis. For 2.5 Years I was resistant, my PSA remained under control around 2 which means the ADT treatment was working. for the next 1.5 years my PSA started to rise, it was a slow rise. I started Pluvicto, 1 shot every 5 weeks, my PSA kept rising, and doubled, But, Pet-Scan indicated my tumors decreased in size and number. My oncologist liked that, but pulled me off Pluvicto to focus on treating my PSA. I start Darolutamide in a few view days.

End of day 2 of session 1. Yesterday was the special scan. No results, yet.
Yesterday, so cold.....long sleeved shirt, light jacket, my big, thick comforter pulled up, my wool jacket over the top, heating pad.
Today, not cold. Go figure.
Bit of hip pain, lots of thigh pain, they say that's normal.
Nap time.

I am 86 and will have my 4th Pluvicto infusion today 6/26/2025.
I had 9 treatments of Chemo. The PSA started out at
86 and got down to 7. Chemo was a real bitch. Then after 11 months the PSA was back up to 80 and I started Pluvicto. My PSA has dropped like a rock. 80 to 40, then 40 to 13 and now 13 to 5.5.
My side effects have been minimum. Way better than chemo.
I am one of the lucky ones that Pluvicto works on!

Willis Beavers

My oncology team, Lynn Cancer Institute in Boca Raton, watches various blood indicators carefully to tell what/how the Pluvicto injections are behaving. I'm told that platelets, thyroid and kidney functions are among the closely monitored indicators. And, can't forget PSA direction but it seems that early on in the injection series you can expect to see the PSA turn up. Hope others can provide more info.

79 years young with metastacized Prostate Cancer in my ribs & backbone. I also have IPF. I have been dealing with the cancer for 4 plus years. Chemo, ADT, direct radiation to the prostate, and now I"ve had two rounds of Pluvicto. Side effects: tiredness (to add to the effect from all the meds), dry mouth, increasing discomfort in my bowels, and a gnawing question about whether its working. My doc won't do another PSMA scan till after the 4th treatment which is frustrating - only way to know if its working or not. No pain from injection - hassle keeping distance from my wife and sleeping in separate rooms ( we like each other) but the tiredness increases and I wonder about other side effects. Thought it good news (at least for the drug company) that they have now approved it for use without chemo or ADT - the idea is great and hope its working and killing the cancer cells. Choose life, fight, fight, fight.

Could have. All things are possible, but not probable.

Promise/Color, oh, you're good, not hereditary, don't have to inform kids.

1.5-2 years later,things don't seem to be following "the plan", onc sent sample off to a lab in Chicago.
Just so you might clearly understand, this was not a NEW biopsy sample, this was a bit of the ORIGINAL biopsy sample.
I suppose sitting in a refrigerated space all that time, the DNA in the sample could have transcended earthly bounds and become something else for the next test.

Nah.

Ooooops. New lab says it IS hereditary, and oh, by the way, it's ATM variant.....and then the onc changed "the plan" because those meds were not best for ATM.

Doesn't matter.
I don't trust medical professionals any more.